[Pulmonary hypertension and myocardial contraction in disseminated types of pulmonary tuberculosis]. / Legochnaia gipertenziia i sokratitel'naia funktsiia miokarda pri pasprostranennykh formakh tuberkuleza legkikh.

To elucidate the influence of hemodynamic factors on the development of right ventricular failure, hemodynamic parameters of the lesser and greater circulations and those characterizing myocardial contractility were studied in 36 patients. Despite profuse lung damage, pulmonary failure, and marked external respiration dysfunction that accompanied disseminated pulmonary tuberculosis, pulmonary hypertension was moderate and failed to be followed by hemodynamic overload, right cardiac hypertrophy and dilatation. Significant reductions in myocardial contractility both of the right and left cavities with a rise in the intensity of an inflammatory process suggest the leading role of a toxic and infectious agent in myocardial damage.

[The effect of an acoustic calling signal on the sex hormone level in the blood of white mice]. / Vliianie akusticheskogo prizyvnogo signala na uroven' polovykh gormonov v krovi belykh myshei.

The action was studied of synthesized acoustic signals, similar to the natural invocatory ones by their characteristics, on the level of sexual hormones in male and female mature laboratory mice, and also the dependence of these hormonal shifts on rhythmic organization of the artificial sound signals. As a result of the experiments it was convincingly shown that synthesized acoustic signal with the frequency of 3500 Hz (S-1) caused a functional load on the glands of internal secretion which was testified by statistically significant increase in the level of sexual hormones in the blood of males (by testosterone and extradiole) and female mice (by extradiole and progesterone). In order to clear up the role of rhythmic organization of signal studies were conducted with the application of synthetic acoustic signal (S-2), different from S-1. The analysis of the data revealed the absence of significant changes in the level of sexual hormones both in males and in females during S-2 sounding.

[Content of middle mass molecules in blood serum of patients with burns after hemosorption treatment]. / Soderzhanie molekul srednei massy v syvorotke krovi bol'nykh s ozhogami pri lechenii gemosorbtsiei.

Content of so-called "middle mass molecules" in blood serum of patients with acute burn toxemia was studied by means of gel filtration on Sephadex G-25. Acute burn toxemia was accompanied by accumulation of the molecules in blood serum of the patients with burns; amount of these molecules correlated with a severity of burn trauma. The "middle mass molecules" were effectively eliminated after haemosorption on a charcoal sorbent SKN.2M. The rate of the "middle mass molecules" elimination in haemosorption correlated with improvement of the patients clinical state, with a decrease in symptoms of intoxication; manifestations of acute psychosis were also decreased.

[Lactate dehydrogenase activity and isoenzyme spectrum in the transplanted sensory and sympathetic ganglia of the rat]. / Aktivnost' i izofermentnyi spektr laktatdegidrogenazy transplantirovannykh sensornykh i simpaticheskikh gangliev krysy.

Total activity, isoenzyme pattern of lactate dehydrogenase (LDH), morphological peculiarities of normal and transplanted in the mesentery for 1-7 and 30 days dorsal root and superior cervical sympathetic ganglia of the adult rats, were analysed. About 30% neurons in sensory ganglia and 5% in sympathetic ganglia were viable 30 days after transplantation. Total LDH activity was 3 times higher in normal sympathetic ganglia compared with that in spinal ganglia. Transplantation leads to a slight rising in total LDH activity in sensory root ganglia and to a slight fall in sympathetic ganglia. Five fractions of LDH in normal sensory ganglia and four fractions in sympathetic ganglia were revealed. Significant rising of M4 isoenzyme activity was characteristic of both sensory and sympathetic ganglia after transplantation for 7 days. Functional significance of the changes observed is discussed.