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1.
Gematol Transfuziol ; 38(7): 31-3, 1993.
Article Ru | MEDLINE | ID: mdl-8307288

Red cell phospholipids and glycerols were measured in 18 normal by peripheral blood hemoglobin, 19 iron deficient (latent deficiency) and in 20 hypoferric anemia females. Latent and manifest iron deficiency caused a pronounced elevation in the levels of glycerols, lysophosphatidylinositols, lysophosphatidylcholines, lysophosphatidylethanolamines, phosphatidylinositol diphosphates and a drop in the phosphatidylserines in erythrocytes. This provokes serious structural and functional alterations in erythrocytic membranes of iron deficient subjects.


Anemia, Hypochromic/blood , Glycerol/blood , Phospholipids/blood , Female , Humans
2.
Ter Arkh ; 63(12): 38-40, 1991.
Article Ru | MEDLINE | ID: mdl-1803598

The dynamics of the content of total lipids (cholesterol and cholesterol esters) was studied in patients with acute large-focal uncomplicated myocardial infarction in different disease periods. Rapid quantitative changes that occur in the content of cholesterol and its esters in the test groups were established to be characterized by marked specificity and by the form of its own in different disease periods (in the acute period--days 2-5 and on day 15--the health status stabilization). It is advisable that the characteristics of the dynamics of rapid reversible changes in the content of total lipids may be used for estimating the status gravity of patients with uncomplicated large-focal myocardial infarction.


Lipids/blood , Myocardial Infarction/blood , Adult , Cholesterol/blood , Cholesterol Esters/blood , Chromatography, Gel/instrumentation , Chromatography, Gel/methods , Humans , Male , Middle Aged , Time Factors
3.
Vopr Med Khim ; 36(2): 80-2, 1990.
Article Ru | MEDLINE | ID: mdl-2363266

A procedure is described which enabled to isolate rapidly at the preparative scale as well as to estimate with high rate of sensitivity the phosphatidyl inositols in mixtures of native lipids. Efficiency of the procedure developed is based on some advantages of the technique of horizontal flow chromatography as well as on use of silica gel containing potassium carbonate obtained after precipitation. Quantitative estimation of phosphatidyl inositols involved densitometry of narrow silica gel strips containing 10-15 samples simultaneously.


Chromatography, Thin Layer/methods , Phosphatidylinositols/isolation & purification , Animals , Brain Chemistry , Liver/analysis , Lung/analysis , Organ Specificity , Rats
4.
Vopr Onkol ; 36(7): 838-41, 1990.
Article Ru | MEDLINE | ID: mdl-2399665

Phosphatidyl inosite level was measured in the whole blood, plasma, erythrocytes and platelets of patients with cancer of various sites (270), benign tumors (50), and hemoblastoses and anemia (60 cases). Phosphatidyl inosite levels in all the substrates in cancer patients, on the average, proved half the normal one while, in the benign tumor group, they only tended to decrease. The levels did not depend upon blood count.


Neoplasms/blood , Phosphatidylinositols/blood , Blood Platelets/analysis , Erythrocytes/analysis , Hematologic Diseases/blood , Humans , Plasma/analysis
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