[Short- and long-term outcomes of laparoscopic interventions in patients with colon cancer: single-centre experience]. / Neposredstvennye i otdalennye rezul'taty laparoskopicheskikh vmeshatel'stv u patsientov s rakom obodochnoi kishki: opyt odnogo tsentra.

OBJECTIVE: To compare short- and long-term outcomes of treatment in patients with colon cancer undergoing laparoscopic and open surgery. MATERIAL AND METHODS: There were 281 patients with colon cancer. All patients underwent open (n=144, 51.2%) or laparoscopic (n=137, 48.8%) procedures. Short- and long-term outcomes of treatment were compared in both groups. RESULTS: There were no significant differences in sex, age, body mass index, location of tumors and tumor differentiation grade in both groups. Conversion was required in 10 (7.2%) cases. The median of duration of surgery was greater for laparoscopic procedures (150 min vs. 130 min; p<0.001). Intraoperative blood loss was significantly less in laparoscopic surgery (100 ml vs. 300 ml; p=0.001). Postoperative mortality was similar (3.5% vs. 2.5%; p=0.5) while incidence of postoperative complications was significantly lower after laparoscopic interventions (13.1% vs. 22.2%; p=0.04). There was earlier recovery of the gastrointestinal tract after laparoscopic procedures (2.1±0.9 days vs. 3.6±1.5 days, respectively; p<0.001). The postoperative hospital-stay was significantly less in the 2nd group (p<0.001). Two-year disease -free and overall survival was similar in both groups. CONCLUSION: Laparoscopic interventions for colon cancer are followed by similar overall and disease-free 2-year survival and better early outcomes.

[The number of life years lost (DALYs) due to premature mortality in the population of Tomsk region in 2012].

AIM: To calculate the index of years of life lost population due to premature death in the Tomsk region in 2012, and the contribution of various groups of diseases in the total indicator DALY among males and females. MATERIALS AND METHODS: In the calculation of DALY used the number and the gender and age structure of the population of Tomsk region by 01.01.2012, according to Rosstat. To conduct the calculation of DALY used the methodology presented by the world Bank in the report "Investing in health" in 1993 According to the methodology, the DALY is the number of years of life of the population, lived with disability or other health problems, and lost due to premature death. RESULTS: The total loss of DALYs in the Tomsk region by the end of 2012 amounted 112,3, per 1000 population (11.6 +/- 8.9). In the structure of DALYs by cause of death 1st place is occupied by diseases of the circulatory system, 2nd injury and poisoning, 3rd neoplasms. CONCLUSIONS: The indicator DALY in the Tomsk region are significantly lower than the Russian Federation as a whole (according to S.A. Leonov--1.25 times, according to G. Yang--2 times). The relatively low level of DALYs in the Tomsk region is associated with favourable compared with other regions of the age structure (younger populations). It should also be noted that more than 70% of population live in urban areas, where, as is known, the availability of medical care are higher than in rural.