Measurement properties of movement smoothness metrics for upper limb reaching movements in people with moderate to severe subacute stroke.

BACKGROUND: Movement smoothness is a potential kinematic biomarker of upper extremity (UE) movement quality and recovery after stroke; however, the measurement properties of available smoothness metrics have been poorly assessed in this group. We aimed to measure the reliability, responsiveness and construct validity of several smoothness metrics. METHODS: This ancillary study of the REM-AVC trial included 31 participants with hemiparesis in the subacute phase of stroke (median time since stroke: 38 days). Assessments performed at inclusion (Day 0, D0) and at the end of a rehabilitation program (Day 30, D30) included the UE Fugl Meyer Assessment (UE-FMA), the Action Research Arm Test (ARAT), and 3D motion analysis of the UE during three reach-to-point movements at a self-selected speed to a target located in front at shoulder height and at 90% of arm length. Four smoothness metrics were computed: a frequency domain smoothness metric, spectral arc length metric (SPARC); and three temporal domain smoothness metrics (TDSM): log dimensionless jerk (LDLJ); number of submovements (nSUB); and normalized average rectified jerk (NARJ). RESULTS: At D30, large clinical and kinematic improvements were observed. Only SPARC and LDLJ had an excellent reliability (intra-class correlation > 0.9) and a low measurement error (coefficient of variation < 10%). SPARC was responsive to changes in movement straightness (rSpearman=0.64) and to a lesser extent to changes in movement duration (rSpearman=0.51) while TDSM were very responsive to changes in movement duration (rSpearman>0.8) and not to changes in movement straightness (non-significant correlations). Most construct validity hypotheses tested were verified except for TDSM with low correlations with clinical metrics at D0 (rSpearman<0.5), ensuing low predictive validity with clinical metrics at D30 (non-significant correlations). CONCLUSIONS: Responsiveness and construct validity of TDSM were hindered by movement duration and/or noise-sensitivity. Based on the present results and concordant literature, we recommend using SPARC rather than TDSM in reaching movements of uncontrolled duration in individuals with spastic paresis after stroke. TRIAL REGISTRATION: NCT01383512, https://clinicaltrials.gov/ , June 27, 2011.

Teaching and Rehabilitation of Handwriting for Children in the Digital Age: Issues and Challenges.

Handwriting is a determining factor for academic success and autonomy for all children. Making knowledge accessible to all is a challenge in the context of inclusive education. Given the neurodevelopmental diversity within a classroom of children, ensuring that the handwriting of all pupils progresses is very demanding for education professionals. The development of tools that can take into account the variability of the profiles and learning abilities of children with handwriting difficulties offers a new potential for the development of specific and adapted remediation strategies. This narrative review aims to present and discuss the challenges of handwriting learning and the opportunities offered by new technologies involving AI for school and health professionals to successfully improve the handwriting skills of all children.

Whole body movement strategies during sit-to-stand and stair ascent in individuals with a lower limb amputation: A systematic review.

BACKGROUND: Individuals with a lower limb amputation use compensatory strategies during essential tasks such as sit-to-stand and stair ascent leading to secondary physical conditions. The ensuing biomechanical parameters outlining the motion strategies they put in place need to be identified and described. METHODS: We searched three databases (Embase, IEEE Xplore and PubMed) for articles on the spatiotemporal, the kinematics and the kinetics that compared the amputated, the intact lower limbs, or the trunk of individuals with a unilateral transtibial or transfemoral amputation with the limbs of a control group. FINDINGS: We found twenty articles. During sit-to-stand, individuals with a lower limb amputation increased the trunk inclination angle toward the intact lower limb, explaining higher ground reaction forces and peak knee sagittal power generation. During stair ascent, individuals with a lower limb amputation increased the stance phase duration on the intact lower limb. Moreover, individuals with a lower limb amputation increased both lower limbs hip extension moment and power, and the amputated lower limb knee extension moment. In both tasks, the individuals with a transfemoral amputation presented larger differences than those with transtibial compared to the control group. INTERPRETATION: Both lower limbs intact joint moment and power were increased to compensate for the prosthesis passive joint and to ensure stability. Stair gait studies mainly focused on the lower limbs' biomechanical changes in the sagittal plane, while sit-to-stand studies focused on asymmetries without comparing the lower limbs independently. Better methodological descriptions are essential to enhance the external validity of previous results.

Balance control deficits in individuals with a transtibial amputation with and without visual input.

BACKGROUND: Many individuals with a transtibial amputation (TTA) exhibit balance deficits after limb loss. However, limited evidence exists on balance deficits of individuals with a TTA using hip, knee, and ankle kinematics and center of mass outcomes. OBJECTIVES: To identify balance control deficits in individuals with a TTA and determine to what extent they are accentuated without visual inputs. STUDY DESIGN: Cross-sectional. METHODS: Ten individuals with TTA and 10 healthy controls undertook a biomechanical assessment during a 30-s quiet standing task with eyes open (EO) and eyes closed (EC). The mean trunk, hip, knee, and ankle angles and center of pressure (COP) and center of mass excursions were calculated. RESULTS: More ankle dorsiflexion was observed for amputated limbs compared with intact lower limbs (mean difference: 5.8-degree, P = 0.031). Less anteroposterior (mean difference: 26.5 mm, P < 0.001) and mediolateral (ML) (mean difference: 4.2 mm, P = 0.042) COP excursions were found for amputated limbs compared with intact lower limbs and for control limbs compared with intact limbs (mean difference: 18.8 mm, P = 0.019). Greater ML COP excursion was found during EC than during EO condition (mean difference: 1.1 mm, P = 0.037). CONCLUSIONS: Individuals with a TTA presented a greater reliance on the intact lower limb, as highlighted by the greater ankle plantarflexion and anteroposterior and ML COP excursions for intact limbs compared with amputated limbs during quiet standing tasks. During EC condition, both groups exhibited greater ML COP excursions compared with EO condition, suggesting less postural stability. These differences may place them at greater risk of falling.

Clinical Walking Tests and Gait Pattern Characterization During 6-Minute Walk Test Using Inertial Sensors: Follow-Up in Individuals With Lower Limb Amputation.

Inertial measurement units and normative values enable clinicians to quantify clinical walking tests and set rehabilitation goals. Objectives of this study were (1) to compare time- and distance-based walking tests in individuals with lower limb amputation (iLLA) and normative values following rehabilitation discharge (T1) and 6 weeks after discharge (T2) and (2) to investigate spatiotemporal and foot kinematic parameters over a 6-minute walk test using inertial measurement units. Twelve iLLA participated in this study. Distance, cadence, stance ratio, loading rate ratio, push-up ratio, path length, and minimum toe clearance were analyzed during 6-minute walk test. Nonparametric repeated-measures analysis of variance tests, Bonferroni corrections, were performed. Time of distance-based walking tests diminished at T2 (P < .02). Compared with normative values, walking performance in iLLA was reduced. Cadence at T2 increased significantly (P = .026). Stance ratio increased in both legs at T2 (P < .05). Push-up ratio tended to decrease at T2 in the amputated leg (P = .0003). Variability of path length and minimum toe clearance at T2 were less than at T1 in the nonamputated leg (P < .05). Spatiotemporal improvement at T2 could be due to prosthesis adaptation in iLLA. The lower performance of the functional walk test compared with normative values could be due to amputation and pain-related fatigue.

Assessment of biomechanical deficits in individuals with a trans-tibial amputation during level gait using one-dimensional statistical parametric mapping.

BACKGROUND: Most previous studies reported biomechanical deficits in individuals with a trans-tibial amputation (TTA) during gait using zero-dimensional analyses. However, these analyses do not allow to precisely determine during which part of the gait cycle these deficits occur. There is a need to use more appropriate methods to map the differences, such as one-dimensional statistical parametric mapping. RESEARCH QUESTION: What are the most relevant phases of the gait cycle during which the biomechanical deficits in TTA occur? METHODS: Eight TTA and 15 healthy counterparts (CON) underwent one biomechanical gait analysis. Pelvis, hip, knee and ankle kinematics, total support moment (TSM) and gastrocnemius lateralis, vastus lateralis and tibialis anterior muscle activity were compared between the amputated (AmLL), the intact (InLL) and the control (CnLL) lower limbs using one-dimensional statistical parametric mapping. RESULTS: More ankle dorsiflexion and knee flexion were observed for the AmLL compared to the InLL and CnLL (ankle only) from the end of the stance phase to the beginning of the swing phase. Less knee flexion was also found for the AmLL during early stance phase. More pelvis posterior tilt and rotation toward the contralateral limb was observed during most of the gait cycle for the AmLL compared to the InLL. TSM was smaller for the AmLL compared to the CnLL during early stance phase. SIGNIFICANCE: Using a one-dimensional statistical parametric mapping approach for TTA gait analysis, this study provides novel insights on their biomechanical gait deficits compared to CON. Greater reliance on the InLL was observed in TTA as suggested by the asymmetric kinematic and kinetic profiles.

Three dimensional validation of an instrumented handrail for stair gait.

Some studies have used load cells (LC) to measure the force applied to horizontal handrails, but no work has validated an inclined set-up that can be used to bring new insights into handrail use during staircase gait. The aim of this study was to validate the accuracy of an inclined handrail set-up instrumented with LC. A handrail set-up designed to be easily reconstructed and integrating two commercial LC is proposed. Twenty points were tested along the handrail, with four reference weights in the three orthogonal directions of the sensors (Medio-Lateral, Antero-Posterior, Vertical). For each direction, the percentage (%) of error and the cross-talk between the known and recorded forces were calculated. A linear regression of the % error was performed to evaluate measurement accuracy in relation to point of application along the handrail. The current easily replicated set-up of an inclined handrail showed accurate measures with low cross-talk. The percentage of error and cross-talk were below 3.7% and 3.7%, respectively, consistent with previous studies evaluating inclined handrail with other methods. The error and cross-talk were greater in the Medio-Lateral and Antero-Posterior directions. The error in the Antero-Posterior direction was larger over the upper part of the handrail.

Evolution of gait parameters in individuals with a lower-limb amputation during a six-minute walk test.

BACKGROUND: A recent amputation leads to decreased functional capacities in the lower limb amputees (LLA), especially during walking. Assessments of LLA's gait in clinical settings are used to provide feedback on their evolution without quantifying gait parameters distinctly, unlike new technologies, such as inertial sensors (IMUs), which have demonstrated their effectiveness in different environments and populations. RESEARCH QUESTION: How do the spatial-temporal gait parameters and kinematics of the LLA evolve quantitatively over a six-minute walk test (6MWT) and is the use of inertial sensors relevant in clinical practice to quantify those parameters? METHODS: Fifteen LLA from a study cohort performed a 6MWT post-rehabilitation, wearing inertial sensors on both feet to provide gait parameters (i.e., minimum toe clearance (minTC), speed, cadence, stance time and foot flat ratio (FFr)) over this test. A non-parametric ANOVA was conducted comparing the evolution of each parameter over the 6MWT (12 intervals of 30 s). Significance level was set at P ≤ 0.05. Post-hoc Wilcoxon signed-rank tests were performed if a main effect was detected. RESULTS: MinTC and stance phase variability along the 6MWT were significantly different over time. Cadence variability and speed variation were significantly different between both feet (amputated and non-amputated leg). SIGNIFICANCE: The increased variability in gait parameters along the 6MWT suggests a greater risk of future mobility problems following a return in community. The data provided by the IMUs reflect the potential of the clinical rehabilitation programme and could, therefore, help clinicians to refine their interventions.