A Method for Locational Risk Estimation of Vehicle-Children Accidents Considering Children's Travel Purposes.

The reduction in locational traffic accident risks through appropriate traffic safety management is important to support, maintain, and improve children's safe and independent mobility. This study proposes and verifies a method to evaluate the risk of elementary school students-vehicle accidents (ESSVAs) at individual intersections on residential roads in Toyohashi city, Japan, considering the difference in travel purposes (i.e., school commuting purpose; SCP or non-school commuting purpose: NSCP), based on a statistical regression model and Empirical Bayes (EB) estimation. The results showed that the ESSVA risk of children's travel in SCP is lower than that in NSCP, and not only ESSVAs in SCP but also most ESSVAs in NSCP occurred on or near the designated school routes. Therefore, it would make sense to implement traffic safety management and measures focusing on school routes. It was also found that the locational ESSVA risk structure is different depending on whether the purpose of the children's travels is SCP or NSCP in the statistical model. Finally, it was suggested that evaluation of locational ESSVA risks based on the EB estimation is useful for efficiently extracting locations where traffic safety measures should be implemented compared to that only based on the number of accidents in the past.

Structure and Reactivity of an Asymmetric Synthetic Mimic of Nitrogenase Cofactor.

The Mo nitrogenase catalyzes the ambient reduction of N2 to NH3 at its M-cluster site. A complex metallocofactor with a core composition of [MoFe7 S9 C], the M-cluster, can be extracted from the protein scaffold and used to facilitate the catalytic reduction of CN- , CO, and CO2 into hydrocarbons in the isolated state. Herein, we report the synthesis, structure, and reactivity of an asymmetric M-cluster analogue with a core composition of [MoFe5 S9 ]. This analogue, referred to as the Mo-cluster, is the first synthetic example of an M-cluster mimic with Fe and Mo positioned at opposite ends of the cluster. Moreover, the ability of the Mo-cluster to reduce C1 substrates to hydrocarbons suggests the feasibility of developing nitrogenase-based biomimetic approaches to recycle C1  waste into fuel products.