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1.
Curr Pharm Des ; 29(21): 1645-1658, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37550904

RESUMEN

This article explores the significant impact of artificial intelligence (AI) and machine learning (ML) on the pharmaceutical industry, which has transformed the drug development process. AI and ML technologies provide powerful tools for analysis, decision-making, and prediction by simplifying complex procedures from drug design to formulation design. These techniques could potentially speed up the development of better medications and drug development processes, improving the lives of millions of people. However, the use of these techniques requires trained personnel and human surveillance for AI to function effectively, if not there is a possibility of errors like security breaches of personal data and bias can also occur. Thus, the present review article discusses the transformative power of AI and ML in the pharmaceutical industry and provides insights into the future of drug development and patient care.


Asunto(s)
Inteligencia Artificial , Aprendizaje Automático , Humanos , Diseño de Fármacos , Desarrollo de Medicamentos , Industria Farmacéutica
2.
Mini Rev Med Chem ; 17(18): 1758-1777, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28969541

RESUMEN

Cancer is one of the most important causes of morbidity and mortality all across the world. On an average, every year approximately 238,000 new cases of brain and other central nervous system tumors are diagnosed around the world. Amongst all, tumors of brain account for nearly 85% to 90% of all primary central nervous system (CNS) tumors. Regardless of tremendous scientific efforts to develop newer diagnostic techniques and latest therapy, the management of brain cancer is still a challenge in neuro-oncology. Inadequate concentration of chemotherapeutics at the site of tumor restricts the complete destruction of malignant cells due to the presence of blood brain barrier. Besides, there is a necessity for improvement in tumor imaging for better characterization and visualization of tumor cells for surgical procedure. Nanoparticles offer the advantages upon many of these concerns i.e., diagnosis, capability to target therapeutic agents to the tumor sites and the ability of getting across the blood-brain barrier. Thus utilization of nanoparticles may lead to breakthrough in brain cancer management.


Asunto(s)
Antineoplásicos/uso terapéutico , Neoplasias Encefálicas/tratamiento farmacológico , Nanopartículas/uso terapéutico , Nanomedicina Teranóstica , Animales , Antineoplásicos/química , Neoplasias Encefálicas/diagnóstico , Humanos , Nanopartículas/química
3.
Chin J Nat Med ; 14(1): 31-9, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26850344

RESUMEN

Delonix regia (Bojer ex Hook) Raffin (Fabaceae), also known as flame of forest, is a semi-deciduous tree, distributed throughout Madagascar, India, Africa, and Northern Australia. Various parts of the plant are traditionally used for the treatment of different ailments such as inflammation, rheumatism, bronchitis, diabetes, anemia, fever, gynecological disorders, and pneumonia. The plant possess antioxidant, hepatoprotective, gastroprotective, wound healing, antiarthritic, larvicidal, antimalarial, antiemetic, antibacterial, antifungal, antiinflammatory, analgesic, antidiarrhoeal, antiheamolytic, diuretic, and anthelmintic activities. This review is an up-to-date compilation on its traditional uses in context to phytochemical and pharmacological perspectives.


Asunto(s)
Fabaceae/química , Extractos Vegetales/farmacología , Animales , Antiinflamatorios/farmacología , Antieméticos/farmacología , Antioxidantes/farmacología , Humanos , Hipoglucemiantes/farmacología , Sustancias Protectoras/farmacología
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