This case report describes an 80-year-old patient's right-sided hemicranial headache, right-sided tongue hemiatrophy with fasciculations and deviation, right side of the tongue on protrusion, and mild dysarthria.
Calcium Pyrophosphate , Hypoglossal Nerve Diseases , Humans , Hypoglossal Nerve Diseases/diagnostic imaging , Hypoglossal Nerve Diseases/etiology , Diphosphates , Tongue/innervation
INTRODUCTION: Prealbumin is a marker of malnutrition and inflammation. It has been associated with poor prognosis in cardiovascular disease, but less is known in stroke patients. Our objective was to evaluate the association of prealbumin levels at admission with prognosis in patients with stroke treated with mechanical thrombectomy. METHODS: Retrospective study of a prospective database of consecutive patients treated with mechanical thrombectomy. Clinical, radiological, and blood parameters including serum prealbumin, and prognostic variables such as respiratory infection, in-hospital mortality, and the modified Rankin scale at 3 months were collected. RESULTS: We included 319 patients between 2018 and 2019. Prealbumin levels were significantly lower in patients older than 80 years, women, patients with a prestroke Rankin score >2, a glomerular filtrate rate <60 mL/min, and in those with atrial fibrillation. Regarding prognostic variables, prealbumin levels were not associated with respiratory infection. Low prealbumin levels were associated with poor functional prognosis (Rankin score >2), in-hospital mortality, and 3-month mortality. In multivariate analysis, prealbumin was an independent risk factor associated with mortality at 3 months, OR 0.92 [0.86-0.98], p = 0.019. CONCLUSION: Lower prealbumin levels at admission behaved as an independent predictor of long-term mortality in patients treated with mechanical thrombectomy. These results should be replicated in other cohorts.
Brain Ischemia , Stroke , Female , Humans , Prealbumin/analysis , Prognosis , Retrospective Studies , Stroke/diagnosis , Stroke/therapy , Thrombectomy/adverse effects , Thrombectomy/methods , Treatment Outcome , Aged, 80 and over
Hereditary angio-oedema with C1 inhibitor deficiency (C1-INH-HAE) type I is a rare immune disorder characterised by a deficit of functional C1 esterase inhibitor (C1-INH). Recurrent C1-INH-HAE attacks typically present as generalised skin swelling and abdominal pain. Neurological involvement is very unusual, with a few reports of cephalea and recurrent dizziness. We describe a woman in her 30s diagnosed with C1-INH-HAE type I who was referred to the emergency department suffering from left hemisensory syndrome, with the initial suspicion of an ischaemic stroke. A few hours after hospital admission, she presented an acute attack of facial swelling and abdominal pain, receiving intravenous C1-INH concentrate with complete resolution of all symptoms, including neurological ones. A complete aetiological study ruled out a stroke. We pointed out that C1-INH-HAE attack can be an unusual stroke mimic that responds favourably to replacement therapy.
Angioedemas, Hereditary , Brain Ischemia , Stroke , Abdominal Pain , Adult , Angioedemas, Hereditary/complications , Angioedemas, Hereditary/diagnosis , Angioedemas, Hereditary/drug therapy , Complement C1 Inhibitor Protein , Female , Humans , Stroke/diagnosis
OBJECTIVE: To describe a case report of trigeminal neuralgia (TN) due to coronavirus disease-2019 (COVID-19). BACKGROUND: In March 2020, the World Health Organization declared COVID-19 as a pandemic. Respiratory system manifestations are dominant in this new disease. However, numerous case series and reviews have been published on the neurological manifestations, highlighting the potential neurotropism of the new coronavirus. METHODS: We describe a clinical case of TN during COVID-19 and we discuss the differential diagnosis and the potential pathogenic mechanism according to the literature. RESULTS: A 65-year-old man with general malaise and typical respiratory symptoms of COVID-19, who presented with paroxysmal lancinating pain in the right V1 trigeminal territory without other neurological symptoms. General blood test and neuroimaging study were normal. A rapid test showed positive IgG and IgM serologies for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The patient was diagnosed with TN secondary to a viral infection by SARS-CoV-2. Facial pain resolved with the improvement of COVID-19. CONCLUSIONS: The new coronavirus SARS-CoV-2 is a possible etiology of secondary TN. Nevertheless, more studies are needed to elucidate the neuropathology of this viral infection.
COVID-19/complications , Trigeminal Neuralgia/virology , Aged , Humans , Male , SARS-CoV-2
Discitis , Spinal Cord Compression , Tuberculosis, Spinal , Cervical Vertebrae/diagnostic imaging , Discitis/complications , Discitis/diagnosis , Humans , Magnetic Resonance Imaging , Spinal Cord Compression/etiology , Thoracic Vertebrae , Tuberculosis, Spinal/complications , Tuberculosis, Spinal/diagnosis
No disponible
Humans , Female , Adult , Complex Regional Pain Syndromes/etiology , Gynecologic Surgical Procedures/adverse effects , Laparoscopy/adverse effects , Complex Regional Pain Syndromes/complications , Myoma/diagnostic imaging , Lower Extremity/diagnostic imaging , Lower Extremity/pathology
