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Int J Tuberc Lung Dis ; 26(1): 44-49, 2022 01 01.
Artículo en Inglés | MEDLINE | ID: mdl-34969428

RESUMEN

BACKGROUND: Adherence to TB treatment and therefore treatment success could be improved using digital adherence technology.OBJECTIVE: To evaluate the effectiveness of a medication event reminder monitor system (MERM) on treatment success and treatment adherence in patients with drug-susceptible pulmonary TB in Perú.METHODS: This was an experimental, randomised, open-label, controlled study conducted among patients in the second phase of TB treatment. The intervention group received their medications through MERM with the support of a treatment monitor, whereas the control group used the usual strategy. Participants were followed until they completed the 54 doses of the second phase of treatment.RESULTS: The study included 53 patients in each group; four in the intervention group withdrew from the study. Treatment success was significantly more frequent in the MERM group (RR 1.15, 95% CI 1.02-1.30; P = 0.0322). There was no significant difference in the adherence outcomes; however, the percentage of patients who missed at least one dose and patients with more than 10% of total doses missed were lower in the intervention group.CONCLUSION: The use of MERM in the second phase of treatment showed a significant improvement in the treatment success rate in patients with drug-susceptible pulmonary TB.


Asunto(s)
Antituberculosos , Tuberculosis Pulmonar , Antituberculosos/uso terapéutico , Monitoreo de Drogas , Humanos , Cumplimiento de la Medicación , Cumplimiento y Adherencia al Tratamiento , Tuberculosis Pulmonar/tratamiento farmacológico
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