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1.
J Med Internet Res ; 26: e47430, 2024 Jan 19.
Artículo en Inglés | MEDLINE | ID: mdl-38241075

RESUMEN

BACKGROUND: Diabetes mellitus (DM) is a major health concern among children with the widespread adoption of advanced technologies. However, concerns are growing about the transparency, replicability, biasedness, and overall validity of artificial intelligence studies in medicine. OBJECTIVE: We aimed to systematically review the reporting quality of machine learning (ML) studies of pediatric DM using the Minimum Information About Clinical Artificial Intelligence Modelling (MI-CLAIM) checklist, a general reporting guideline for medical artificial intelligence studies. METHODS: We searched the PubMed and Web of Science databases from 2016 to 2020. Studies were included if the use of ML was reported in children with DM aged 2 to 18 years, including studies on complications, screening studies, and in silico samples. In studies following the ML workflow of training, validation, and testing of results, reporting quality was assessed via MI-CLAIM by consensus judgments of independent reviewer pairs. Positive answers to the 17 binary items regarding sufficient reporting were qualitatively summarized and counted as a proxy measure of reporting quality. The synthesis of results included testing the association of reporting quality with publication and data type, participants (human or in silico), research goals, level of code sharing, and the scientific field of publication (medical or engineering), as well as with expert judgments of clinical impact and reproducibility. RESULTS: After screening 1043 records, 28 studies were included. The sample size of the training cohort ranged from 5 to 561. Six studies featured only in silico patients. The reporting quality was low, with great variation among the 21 studies assessed using MI-CLAIM. The number of items with sufficient reporting ranged from 4 to 12 (mean 7.43, SD 2.62). The items on research questions and data characterization were reported adequately most often, whereas items on patient characteristics and model examination were reported adequately least often. The representativeness of the training and test cohorts to real-world settings and the adequacy of model performance evaluation were the most difficult to judge. Reporting quality improved over time (r=0.50; P=.02); it was higher than average in prognostic biomarker and risk factor studies (P=.04) and lower in noninvasive hypoglycemia detection studies (P=.006), higher in studies published in medical versus engineering journals (P=.004), and higher in studies sharing any code of the ML pipeline versus not sharing (P=.003). The association between expert judgments and MI-CLAIM ratings was not significant. CONCLUSIONS: The reporting quality of ML studies in the pediatric population with DM was generally low. Important details for clinicians, such as patient characteristics; comparison with the state-of-the-art solution; and model examination for valid, unbiased, and robust results, were often the weak points of reporting. To assess their clinical utility, the reporting standards of ML studies must evolve, and algorithms for this challenging population must become more transparent and replicable.


Asunto(s)
Inteligencia Artificial , Diabetes Mellitus , Humanos , Niño , Reproducibilidad de los Resultados , Aprendizaje Automático , Diabetes Mellitus/diagnóstico , Lista de Verificación
2.
J Air Waste Manag Assoc ; 73(1): 40-49, 2023 01.
Artículo en Inglés | MEDLINE | ID: mdl-35905292

RESUMEN

Due to the high consumption of Medium-density fiberboard (MDF), waste products of this material are growing worldwide. In this research, the feasibility of using Medium-density fiberboard waste ash (MDFWA) as part of cement in concrete was investigated. For this purpose, 0, 5, 10, 15, 20, and 25% of the cement in concrete was substituted with MDFWA. For all design mixes, the water/blind ratio and the volume of aggregates were same. The slump, compressive strengths, SEM, EDX, TGA, DSC, and FTIR tests were conducted on the samples. At 28 days, the results demonstrated that the compressive strength of the sample containing 20% MDFWA increased by 13.6% compared to the control sample. Furthermore, the microstructure of the concrete show that the voids of the sample containing 20% MDFWA reduced compared to the control sample and also more calcium silicate hydrate (C-S-H) crystal formed.Implications: The significance of the present paper is to solve the environmental issue caused by large amount of Medium-density fiberboard waste ash (MDFWA) and produce also sustainable concrete. In addition, the replacement of cement with MDFWA increases the compressive strength and enhancement of the microstructure of concrete due to extra C-S-H products. Therefore, the findings confirm that by using 20% MDFWA, a more eco-friendly production, denser, sustainable, economical, and stronger concrete would be achieved.


Asunto(s)
Materiales de Construcción , Silicatos , Residuos , Compuestos de Calcio
3.
Comput Intell Neurosci ; 2022: 5054641, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36268157

RESUMEN

With the emergence of the Internet of Things (IoT), investigation of different diseases in healthcare improved, and cloud computing helped to centralize the data and to access patient records throughout the world. In this way, the electrocardiogram (ECG) is used to diagnose heart diseases or abnormalities. The machine learning techniques have been used previously but are feature-based and not as accurate as transfer learning; the proposed development and validation of embedded device prove ECG arrhythmia by using the transfer learning (DVEEA-TL) model. This model is the combination of hardware, software, and two datasets that are augmented and fused and further finds the accuracy results in high proportion as compared to the previous work and research. In the proposed model, a new dataset is made by the combination of the Kaggle dataset and the other, which is made by taking the real-time healthy and unhealthy datasets, and later, the AlexNet transfer learning approach is applied to get a more accurate reading in terms of ECG signals. In this proposed research, the DVEEA-TL model diagnoses the heart abnormality in respect of accuracy during the training and validation stages as 99.9% and 99.8%, respectively, which is the best and more reliable approach as compared to the previous research in this field.


Asunto(s)
Arritmias Cardíacas , Electrocardiografía , Humanos , Electrocardiografía/métodos , Arritmias Cardíacas/diagnóstico , Nube Computacional , Aprendizaje Automático , Programas Informáticos
4.
Comput Biol Med ; 150: 106019, 2022 11.
Artículo en Inglés | MEDLINE | ID: mdl-36162198

RESUMEN

In recent years, the global Internet of Medical Things (IoMT) industry has evolved at a tremendous speed. Security and privacy are key concerns on the IoMT, owing to the huge scale and deployment of IoMT networks. Machine learning (ML) and blockchain (BC) technologies have significantly enhanced the capabilities and facilities of healthcare 5.0, spawning a new area known as "Smart Healthcare." By identifying concerns early, a smart healthcare system can help avoid long-term damage. This will enhance the quality of life for patients while reducing their stress and healthcare costs. The IoMT enables a range of functionalities in the field of information technology, one of which is smart and interactive health care. However, combining medical data into a single storage location to train a powerful machine learning model raises concerns about privacy, ownership, and compliance with greater concentration. Federated learning (FL) overcomes the preceding difficulties by utilizing a centralized aggregate server to disseminate a global learning model. Simultaneously, the local participant keeps control of patient information, assuring data confidentiality and security. This article conducts a comprehensive analysis of the findings on blockchain technology entangled with federated learning in healthcare. 5.0. The purpose of this study is to construct a secure health monitoring system in healthcare 5.0 by utilizing a blockchain technology and Intrusion Detection System (IDS) to detect any malicious activity in a healthcare network and enables physicians to monitor patients through medical sensors and take necessary measures periodically by predicting diseases. The proposed system demonstrates that the approach is optimized effectively for healthcare monitoring. In contrast, the proposed healthcare 5.0 system entangled with FL Approach achieves 93.22% accuracy for disease prediction, and the proposed RTS-DELM-based secure healthcare 5.0 system achieves 96.18% accuracy for the estimation of intrusion detection.


Asunto(s)
Cadena de Bloques , Humanos , Calidad de Vida , Tecnología , Instituciones de Salud , Atención a la Salud
5.
Comput Biol Med ; 149: 105975, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-36057197

RESUMEN

In this study, a novel approach is proposed for glucose regulation in type-I diabetes patients. Unlike most studies, the glucose-insulin metabolism is considered to be uncertain. A new approach on the basis of the Immersion and Invariance (I&I) theorem is presented to derive the adaptation rules for the unknown parameters. Also, a new deep learned type-II fuzzy logic system (T2FLS) is proposed to compensate the estimation errors and guarantee stability. The suggested T2FLS is tuned by the singular value decomposition (SVD) method and adaptive tuning rules that are extracted from stability investigation. To evaluate the performance, the modified Bergman model (BM) is applied. Besides the dynamic uncertainties, the meal effect on glucose level is also considered. The meal effect is defined as the effect of edibles. Similar to the patient activities, the edibles can also have a major impact on the glucose level. Furthermore, to assess the effect of patient informal activities and the effect of other illnesses, a high random perturbation is applied to glucose-insulin dynamics. The effectiveness of the suggested approach is demonstrated by comparing the simulation results with some other methods. Simulations show that the glucose level is well regulated by the suggested method after a short time. By examination on some patients with various diabetic condition, it is seen that the suggested approach is well effective, and the glucose level of patients lies in the desired range in more than 99% h.


Asunto(s)
Aprendizaje Profundo , Diabetes Mellitus Tipo 1 , Algoritmos , Glucemia/metabolismo , Simulación por Computador , Lógica Difusa , Humanos , Inmersión , Insulina
6.
Comput Struct Biotechnol J ; 20: 4733-4745, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36147663

RESUMEN

Detection and Classification of a brain tumor is an important step to better understanding its mechanism. Magnetic Reasoning Imaging (MRI) is an experimental medical imaging technique that helps the radiologist find the tumor region. However, it is a time taking process and requires expertise to test the MRI images, manually. Nowadays, the advancement of Computer-assisted Diagnosis (CAD), machine learning, and deep learning in specific allow the radiologist to more reliably identify brain tumors. The traditional machine learning methods used to tackle this problem require a handcrafted feature for classification purposes. Whereas deep learning methods can be designed in a way to not require any handcrafted feature extraction while achieving accurate classification results. This paper proposes two deep learning models to identify both binary (normal and abnormal) and multiclass (meningioma, glioma, and pituitary) brain tumors. We use two publicly available datasets that include 3064 and 152 MRI images, respectively. To build our models, we first apply a 23-layers convolution neural network (CNN) to the first dataset since there is a large number of MRI images for the training purpose. However, when dealing with limited volumes of data, which is the case in the second dataset, our proposed "23-layers CNN" architecture faces overfitting problem. To address this issue, we use transfer learning and combine VGG16 architecture along with the reflection of our proposed "23 layers CNN" architecture. Finally, we compare our proposed models with those reported in the literature. Our experimental results indicate that our models achieve up to 97.8% and 100% classification accuracy for our employed datasets, respectively, exceeding all other state-of-the-art models. Our proposed models, employed datasets, and all the source codes are publicly available at: (https://github.com/saikat15010/Brain-Tumor-Detection).

7.
Front Med (Lausanne) ; 9: 829055, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35935783

RESUMEN

In recent decades, the use of sensors has dramatically grown to monitor human body activities and maintain the health status. In this application, routing and secure data transmission are very important to prevent the unauthorized access by attackers to health data. In this article, we propose a secure routing scheme called SecAODV for heterogeneous wireless body sensor networks. SecAODV has three phases: bootstrapping, routing between cluster head nodes, and communication security. In the bootstrapping phase, the base station loads system parameters and encryption functions in the memory of sensor nodes. In the routing phase, each cluster head node calculates its degree based on several parameters, including, distance, residual energy, link quality, and the number of hops, to decide for rebroadcasting the route request (RREQ) message. In the communication security phase, a symmetric cryptography method is used to protect intra-cluster communications. Also, an asymmetric cryptography method is used to secure communication links between cluster head nodes. The proposed secure routing scheme is simulated in the network simulator version 2 (NS2) simulator. The simulation results are compared with the secure multi tier energy-efficient routing scheme (SMEER) and the centralized low-energy adaptive clustering hierarchy (LEACH-C). The results show that SecAODV improves end-to-end delay, throughput, energy consumption, packet delivery rate (PDR), and packet loss rate (PLR).

8.
Comput Intell Neurosci ; 2022: 2650742, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35909844

RESUMEN

A genetic disorder is a serious disease that affects a large number of individuals around the world. There are various types of genetic illnesses, however, we focus on mitochondrial and multifactorial genetic disorders for prediction. Genetic illness is caused by a number of factors, including a defective maternal or paternal gene, excessive abortions, a lack of blood cells, and low white blood cell count. For premature or teenage life development, early detection of genetic diseases is crucial. Although it is difficult to forecast genetic disorders ahead of time, this prediction is very critical since a person's life progress depends on it. Machine learning algorithms are used to diagnose genetic disorders with high accuracy utilizing datasets collected and constructed from a large number of patient medical reports. A lot of studies have been conducted recently employing genome sequencing for illness detection, but fewer studies have been presented using patient medical history. The accuracy of existing studies that use a patient's history is restricted. The internet of medical things (IoMT) based proposed model for genetic disease prediction in this article uses two separate machine learning algorithms: support vector machine (SVM) and K-Nearest Neighbor (KNN). Experimental results show that SVM has outperformed the KNN and existing prediction methods in terms of accuracy. SVM achieved an accuracy of 94.99% and 86.6% for training and testing, respectively.


Asunto(s)
Aprendizaje Automático , Máquina de Vectores de Soporte , Adolescente , Algoritmos , Análisis por Conglomerados , Humanos
9.
Comput Intell Neurosci ; 2022: 6852845, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35958748

RESUMEN

According to the World Health Organization (WHO) report, heart disease is spreading throughout the world very rapidly and the situation is becoming alarming in people aged 40 or above (Xu, 2020). Different methods and procedures are adopted to detect and diagnose heart abnormalities. Data scientists are working on finding the different methods with the required accuracy (Strodthoff et al., 2021). Electrocardiogram (ECG) is the procedure to find the heart condition in the waveform. For ages, the machine learning techniques, which are feature based, played a vital role in the medical sciences and centralized the data in cloud computing and having access throughout the world. Furthermore, deep learning or transfer learning widens the vision and introduces different transfer learning methods to ensure accuracy and time management to detect the ECG in a better way in comparison to the previous and machine learning methods. Hence, it is said that transfer learning has turned world research into more appropriate and innovative research. Here, the proposed comparison and accuracy analysis of different transfer learning methods by using ECG classification for detecting ECG Arrhythmia (CAA-TL). The CAA-TL model has the multiclassification of the ECG dataset, which has been taken from Kaggle. Some of the healthy and unhealthy datasets have been taken in real-time, augmented, and fused with the Kaggle dataset, i.e., Massachusetts Institute of Technology-Beth Israel Hospital (MIT-BIH dataset). The CAA-TL worked on the accuracy of heart problem detection by using different methods like ResNet50, AlexNet, and SqueezeNet. All three deep learning methods showed remarkable accuracy, which is improved from the previous research. The comparison of different deep learning approaches with respect to layers widens the research and gives the more clarity and accuracy and at the same time finds it time-consuming while working with multiclassification with massive dataset of ECG. The implementation of the proposed method showed an accuracy of 98.8%, 90.08%, and 91% for AlexNet, SqueezeNet, and ResNet50, respectively.


Asunto(s)
Aprendizaje Profundo , Arritmias Cardíacas/diagnóstico , Nube Computacional , Electrocardiografía/métodos , Humanos , Aprendizaje Automático
10.
Math Biosci Eng ; 19(10): 9749-9768, 2022 07 06.
Artículo en Inglés | MEDLINE | ID: mdl-36031966

RESUMEN

The main aim of the study is to investigate the growth of oyster mushrooms in two substrates, namely straw and wheat straw. In the following, the study moves towards modeling and optimization of the production yield by considering the energy consumption, water consumption, total income and environmental impacts as the dependent variables. Accordingly, life cycle assessment (LCA) platform was developed for achieving the environmental impacts of the studied scenarios. The next step developed an ANN-based model for the prediction of dependent variables. Finally, optimization was performed using response surface methodology (RSM) by fitting quadratic equations for generating the required factors. According to the results, the optimum condition for the production of OM from waste paper can be found in the paper portion range of 20% and the wheat straw range of 80% with a production yield of about 4.5 kg and a higher net income of 16.54 $ in the presence of the lower energy and water consumption by about 361.5 kWh and 29.53 kg, respectively. The optimum condition delivers lower environmental impacts on Human Health, Ecosystem Quality, Climate change, and Resources by about 5.64 DALY, 8.18 PDF*m2*yr, 89.77 g CO2 eq and 1707.05 kJ, respectively. It can be concluded that, sustainable production of OM can be achieved in line with the policy used to produce alternative food source from waste management techniques.


Asunto(s)
Pleurotus , Ecosistema , Ambiente , Humanos , Redes Neurales de la Computación
11.
Front Public Health ; 10: 869238, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35812486

RESUMEN

Early diagnosis, prioritization, screening, clustering, and tracking of patients with COVID-19, and production of drugs and vaccines are some of the applications that have made it necessary to use a new style of technology to involve, manage, and deal with this epidemic. Strategies backed by artificial intelligence (A.I.) and the Internet of Things (IoT) have been undeniably effective to understand how the virus works and prevent it from spreading. Accordingly, the main aim of this survey is to critically review the ML, IoT, and the integration of IoT and ML-based techniques in the applications related to COVID-19, from the diagnosis of the disease to the prediction of its outbreak. According to the main findings, IoT provided a prompt and efficient approach to tracking the disease spread. On the other hand, most of the studies developed by ML-based techniques aimed at the detection and handling of challenges associated with the COVID-19 pandemic. Among different approaches, Convolutional Neural Network (CNN), Support Vector Machine, Genetic CNN, and pre-trained CNN, followed by ResNet have demonstrated the best performances compared to other methods.


Asunto(s)
COVID-19 , Internet de las Cosas , Aprendizaje Automático , Inteligencia Artificial , COVID-19/epidemiología , Humanos , Redes Neurales de la Computación , Pandemias/prevención & control , Máquina de Vectores de Soporte
12.
Math Biosci Eng ; 19(8): 7978-8002, 2022 05 30.
Artículo en Inglés | MEDLINE | ID: mdl-35801453

RESUMEN

Cancer is a manifestation of disorders caused by the changes in the body's cells that go far beyond healthy development as well as stabilization. Breast cancer is a common disease. According to the stats given by the World Health Organization (WHO), 7.8 million women are diagnosed with breast cancer. Breast cancer is the name of the malignant tumor which is normally developed by the cells in the breast. Machine learning (ML) approaches, on the other hand, provide a variety of probabilistic and statistical ways for intelligent systems to learn from prior experiences to recognize patterns in a dataset that can be used, in the future, for decision making. This endeavor aims to build a deep learning-based model for the prediction of breast cancer with a better accuracy. A novel deep extreme gradient descent optimization (DEGDO) has been developed for the breast cancer detection. The proposed model consists of two stages of training and validation. The training phase, in turn, consists of three major layers data acquisition layer, preprocessing layer, and application layer. The data acquisition layer takes the data and passes it to preprocessing layer. In the preprocessing layer, noise and missing values are converted to the normalized which is then fed to the application layer. In application layer, the model is trained with a deep extreme gradient descent optimization technique. The trained model is stored on the server. In the validation phase, it is imported to process the actual data to diagnose. This study has used Wisconsin Breast Cancer Diagnostic dataset to train and test the model. The results obtained by the proposed model outperform many other approaches by attaining 98.73 % accuracy, 99.60% specificity, 99.43% sensitivity, and 99.48% precision.


Asunto(s)
Neoplasias de la Mama , Mama , Neoplasias de la Mama/diagnóstico , Femenino , Humanos , Aprendizaje Automático
13.
Physiol Meas ; 43(8)2022 08 03.
Artículo en Inglés | MEDLINE | ID: mdl-35803247

RESUMEN

Objective.Myocardial infarction (MI) results in heart muscle injury due to receiving insufficient blood flow. MI is the most common cause of mortality in middle-aged and elderly individuals worldwide. To diagnose MI, clinicians need to interpret electrocardiography (ECG) signals, which requires expertise and is subject to observer bias. Artificial intelligence-based methods can be utilized to screen for or diagnose MI automatically using ECG signals.Approach.In this work, we conducted a comprehensive assessment of artificial intelligence-based approaches for MI detection based on ECG and some other biophysical signals, including machine learning (ML) and deep learning (DL) models. The performance of traditional ML methods relies on handcrafted features and manual selection of ECG signals, whereas DL models can automate these tasks.Main results.The review observed that deep convolutional neural networks (DCNNs) yielded excellent classification performance for MI diagnosis, which explains why they have become prevalent in recent years.Significance.To our knowledge, this is the first comprehensive survey of artificial intelligence techniques employed for MI diagnosis using ECG and some other biophysical signals.


Asunto(s)
Inteligencia Artificial , Infarto del Miocardio , Anciano , Electrocardiografía/métodos , Humanos , Aprendizaje Automático , Persona de Mediana Edad , Infarto del Miocardio/diagnóstico , Redes Neurales de la Computación
14.
Front Public Health ; 10: 924432, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35859776

RESUMEN

Cancer is a major public health issue in the modern world. Breast cancer is a type of cancer that starts in the breast and spreads to other parts of the body. One of the most common types of cancer that kill women is breast cancer. When cells become uncontrollably large, cancer develops. There are various types of breast cancer. The proposed model discussed benign and malignant breast cancer. In computer-aided diagnosis systems, the identification and classification of breast cancer using histopathology and ultrasound images are critical steps. Investigators have demonstrated the ability to automate the initial level identification and classification of the tumor throughout the last few decades. Breast cancer can be detected early, allowing patients to obtain proper therapy and thereby increase their chances of survival. Deep learning (DL), machine learning (ML), and transfer learning (TL) techniques are used to solve many medical issues. There are several scientific studies in the previous literature on the categorization and identification of cancer tumors using various types of models but with some limitations. However, research is hampered by the lack of a dataset. The proposed methodology is created to help with the automatic identification and diagnosis of breast cancer. Our main contribution is that the proposed model used the transfer learning technique on three datasets, A, B, C, and A2, A2 is the dataset A with two classes. In this study, ultrasound images and histopathology images are used. The model used in this work is a customized CNN-AlexNet, which was trained according to the requirements of the datasets. This is also one of the contributions of this work. The results have shown that the proposed system empowered with transfer learning achieved the highest accuracy than the existing models on datasets A, B, C, and A2.


Asunto(s)
Neoplasias de la Mama , Redes Neurales de la Computación , Neoplasias de la Mama/diagnóstico por imagen , Femenino , Humanos , Aprendizaje Automático
15.
Sensors (Basel) ; 22(12)2022 Jun 11.
Artículo en Inglés | MEDLINE | ID: mdl-35746208

RESUMEN

The convolutional neural network (CNN) has become a powerful tool in machine learning (ML) that is used to solve complex problems such as image recognition, natural language processing, and video analysis. Notably, the idea of exploring convolutional neural network architecture has gained substantial attention as well as popularity. This study focuses on the intrinsic various CNN architectures: LeNet, AlexNet, VGG16, ResNet-50, and Inception-V1, which have been scrutinized and compared with each other for the detection of lung cancer using publicly available LUNA16 datasets. Furthermore, multiple performance optimizers: root mean square propagation (RMSProp), adaptive moment estimation (Adam), and stochastic gradient descent (SGD), were applied for this comparative study. The performances of the three CNN architectures were measured for accuracy, specificity, sensitivity, positive predictive value, false omission rate, negative predictive value, and F1 score. The experimental results showed that the CNN AlexNet architecture with the SGD optimizer achieved the highest validation accuracy for CT lung cancer with an accuracy of 97.42%, misclassification rate of 2.58%, 97.58% sensitivity, 97.25% specificity, 97.58% positive predictive value, 97.25% negative predictive value, false omission rate of 2.75%, and F1 score of 97.58%. AlexNet with the SGD optimizer was the best and outperformed compared to the other state-of-the-art CNN architectures.


Asunto(s)
Neoplasias Pulmonares , Redes Neurales de la Computación , Humanos , Neoplasias Pulmonares/diagnóstico , Aprendizaje Automático , Tomografía Computarizada por Rayos X
16.
Front Public Health ; 10: 769692, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35747775

RESUMEN

One of the most common causes of death from cancer for both women and men is lung cancer. Lung nodules are critical for the screening of cancer and early recognition permits treatment and enhances the rate of rehabilitation in patients. Although a lot of work is being done in this area, an increase in accuracy is still required to swell patient persistence rate. However, traditional systems do not segment cancer cells of different forms accurately and no system attained greater reliability. An effective screening procedure is proposed in this work to not only identify lung cancer lesions rapidly but to increase accuracy. In this procedure, Otsu thresholding segmentation is utilized to accomplish perfect isolation of the selected area, and the cuckoo search algorithm is utilized to define the best characteristics for partitioning cancer nodules. By using a local binary pattern, the relevant features of the lesion are retrieved. The CNN classifier is designed to spot whether a lung lesion is malicious or non-malicious based on the retrieved features. The proposed framework achieves an accuracy of 96.97% percent. The recommended study reveals that accuracy is improved, and the results are compiled using Particle swarm optimization and genetic algorithms.


Asunto(s)
Neoplasias Pulmonares , Tomografía Computarizada por Rayos X , Algoritmos , Femenino , Humanos , Neoplasias Pulmonares/diagnóstico por imagen , Redes Neurales de la Computación , Reproducibilidad de los Resultados , Tomografía Computarizada por Rayos X/métodos
17.
Front Oncol ; 12: 834028, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35769710

RESUMEN

Breast cancer is the most menacing cancer among all types of cancer in women around the globe. Early diagnosis is the only way to increase the treatment options which then decreases the death rate and increases the chance of survival in patients. However, it is a challenging task to differentiate abnormal breast tissues from normal tissues because of their structure and unclear boundaries. Therefore, early and accurate diagnosis and classification of breast lesions into malignant or benign lesions is an active domain of research. Over the decade, numerous artificial neural network (ANN)-based techniques were adopted in order to diagnose and classify breast cancer due to the unique characteristics of learning key features from complex data via a training process. However, these schemes have limitations like slow convergence and longer training time. To address the above mentioned issues, this paper employs a meta-heuristic algorithm for tuning the parameters of the neural network. The main novelty of this work is the computer-aided diagnosis scheme for detecting abnormalities in breast ultrasound images by integrating a wavelet neural network (WNN) and the grey wolf optimization (GWO) algorithm. Here, breast ultrasound (US) images are preprocessed with a sigmoid filter followed by interference-based despeckling and then by anisotropic diffusion. The automatic segmentation algorithm is adopted to extract the region of interest, and subsequently morphological and texture features are computed. Finally, the GWO-tuned WNN is exploited to accomplish the classification task. The classification performance of the proposed scheme is validated on 346 ultrasound images. Efficiency of the proposed methodology is evaluated by computing the confusion matrix and receiver operating characteristic (ROC) curve. Numerical analysis revealed that the proposed work can yield higher classification accuracy when compared to the prevailing methods and thereby proves its potential in effective breast tumor detection and classification. The proposed GWO-WNN method (98%) gives better accuracy than other methods like SOM-SVM (87.5), LOFA-SVM (93.62%), MBA-RF (96.85%), and BAS-BPNN (96.3%).

18.
Comput Biol Med ; 146: 105511, 2022 07.
Artículo en Inglés | MEDLINE | ID: mdl-35490641

RESUMEN

Accurate simulation of tumor growth during chemotherapy has significant potential to alleviate the risk of unknown side effects and optimize clinical trials. In this study, a 3D simulation model encompassing angiogenesis and tumor growth was developed to identify the vascular endothelial growth factor (VEGF) concentration and visualize the formation of a microvascular network. Accordingly, three anti-angiogenic drugs (Bevacizumab, Ranibizumab, and Brolucizumab) at different concentrations were evaluated in terms of their efficacy. Moreover, comprehensive mechanisms of tumor cell proliferation and endothelial cell angiogenesis are proposed to provide accurate predictions for optimizing drug treatments. The evaluation of simulation output data can extract additional features such as tumor volume, tumor cell number, and the length of new vessels using machine learning (ML) techniques. These were investigated to examine the different stages of tumor growth and the efficacy of different drugs. The results indicate that brolucizuman has the best efficacy by decreasing the length of sprouting new vessels by up to 16%. The optimal concentration was obtained at 10 mol m-3 with an effectiveness percentage of 42% at 20 days post-treatment. Furthermore, by performing comparative analysis, the best ML method (matching the performance of the reference simulations) was identified as reinforcement learning with a 3.3% mean absolute error (MAE) and an average accuracy of 94.3%.


Asunto(s)
Inhibidores de la Angiogénesis , Neoplasias , Inhibidores de la Angiogénesis/efectos adversos , Simulación por Computador , Humanos , Aprendizaje Automático , Neoplasias/patología , Neovascularización Patológica/tratamiento farmacológico , Ranibizumab/efectos adversos , Factor A de Crecimiento Endotelial Vascular
19.
Sensors (Basel) ; 22(10)2022 May 18.
Artículo en Inglés | MEDLINE | ID: mdl-35632242

RESUMEN

Oral cancer is a dangerous and extensive cancer with a high death ratio. Oral cancer is the most usual cancer in the world, with more than 300,335 deaths every year. The cancerous tumor appears in the neck, oral glands, face, and mouth. To overcome this dangerous cancer, there are many ways to detect like a biopsy, in which small chunks of tissues are taken from the mouth and tested under a secure and hygienic microscope. However, microscope results of tissues to detect oral cancer are not up to the mark, a microscope cannot easily identify the cancerous cells and normal cells. Detection of cancerous cells using microscopic biopsy images helps in allaying and predicting the issues and gives better results if biologically approaches apply accurately for the prediction of cancerous cells, but during the physical examinations microscopic biopsy images for cancer detection there are major chances for human error and mistake. So, with the development of technology deep learning algorithms plays a major role in medical image diagnosing. Deep learning algorithms are efficiently developed to predict breast cancer, oral cancer, lung cancer, or any other type of medical image. In this study, the proposed model of transfer learning model using AlexNet in the convolutional neural network to extract rank features from oral squamous cell carcinoma (OSCC) biopsy images to train the model. Simulation results have shown that the proposed model achieved higher classification accuracy 97.66% and 90.06% of training and testing, respectively.


Asunto(s)
Carcinoma de Células Escamosas , Neoplasias de Cabeza y Cuello , Neoplasias de la Boca , Biopsia , Carcinoma de Células Escamosas/diagnóstico , Humanos , Procesamiento de Imagen Asistido por Computador/métodos , Aprendizaje Automático , Neoplasias de la Boca/diagnóstico , Carcinoma de Células Escamosas de Cabeza y Cuello
20.
Sensors (Basel) ; 22(9)2022 May 04.
Artículo en Inglés | MEDLINE | ID: mdl-35591194

RESUMEN

Precipitation in any form-such as rain, snow, and hail-can affect day-to-day outdoor activities. Rainfall prediction is one of the challenging tasks in weather forecasting process. Accurate rainfall prediction is now more difficult than before due to the extreme climate variations. Machine learning techniques can predict rainfall by extracting hidden patterns from historical weather data. Selection of an appropriate classification technique for prediction is a difficult job. This research proposes a novel real-time rainfall prediction system for smart cities using a machine learning fusion technique. The proposed framework uses four widely used supervised machine learning techniques, i.e., decision tree, Naïve Bayes, K-nearest neighbors, and support vector machines. For effective prediction of rainfall, the technique of fuzzy logic is incorporated in the framework to integrate the predictive accuracies of the machine learning techniques, also known as fusion. For prediction, 12 years of historical weather data (2005 to 2017) for the city of Lahore is considered. Pre-processing tasks such as cleaning and normalization were performed on the dataset before the classification process. The results reflect that the proposed machine learning fusion-based framework outperforms other models.


Asunto(s)
Lógica Difusa , Aprendizaje Automático , Teorema de Bayes , Ciudades , Máquina de Vectores de Soporte
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