RESUMEN
BACKGROUND: Previous studies in pregnancy have not focused in evaluating the effect of walking during pregnancy and prevention of insomnia. Our general objective is to determine the effect of a walking program in preventing the appearance of insomnia in the third trimester of pregnancy, increasing sleep quality and improving quality of life throughout pregnancy. METHODS: Randomized Controlled trial in parallel in healthy sedentary pregnant women (n = 265), Walking_Preg Project (WPP), from university hospital in Granada, Spain. At 12th gestational week (GW), they will be invited to participate and randomly assigned to one of the three arms of study: the intervention group I1 (pedometer, goal of 11,000 steps/day), intervention group I2 (pedometer, no goal) and control (no pedometer). Duration of intervention: 13-32 GW. At 12th, 19th and 31st GW the average steps/day will be measured in groups I1 and I2. At 13th, 20th and 32nd GW, Athens Insomnia Scale (AIS), Pittsburgh Sleep Quality Index (PSQI), Adherence to Mediterranean Diet (AMD), physical activity (short IPAQ), quality of life (PSI), and consumption of toxic substances (caffeine, illegal drugs, alcohol and tobacco) will be collected. Student t test or Mann-Whitney U will be used to compare 19th and 31st GW mean of daily steps between I1 and I2 groups. To compare differences between groups in terms of frequency of insomnia/quality of life for each trimester of pregnancy, Pearson's Chi-square test or Fisher's exact test will be used. To determine differences in hours of sleep and quality of sleep throughout each trimester of pregnancy, analysis of variance or Friedman test will be used. McNemar-Bowker test will be used to assess differences in life quality in pre-post analyses in the 3 arms. We will use Stata 15 statistical software. DISCUSSION: promoting walking in second half of pregnancy through use of pedometer and health pre-registration of a goal to be achieved -'10,000-11,000 steps a day'- should prevent appearance of insomnia in third trimester, will increase sleep quality and quality of life in pregnant women. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03735381 . Registered 8th November, 2018.
Asunto(s)
Complicaciones del Embarazo/prevención & control , Trastornos del Inicio y del Mantenimiento del Sueño/prevención & control , Caminata , Actigrafía , Femenino , Humanos , Embarazo , Tercer Trimestre del Embarazo , Ensayos Clínicos Controlados Aleatorios como Asunto/métodosRESUMEN
OBJECTIVE: To analyze the effect of learning in two surgeons on complications and conversion to laparotomy during total and subtotal laparoscopic hysterectomy. MATERIAL AND METHODS: We analyzed retrospectively 236 total and subtotal laparoscopic hysterectomies done by two surgeons from the time they first performed the procedure. The interventions were classified in three groups based on the surgeon's experience: the first 75 hysterectomies ("novice period"), the subsequent 75 hysterectomies ("intermediate"), and the subsequent 86 hysterectomies ("routine period"). RESULTS: Patient's characteristics changed as surgeons gained experience, with more complex operations (greater obesity, previous surgery and malignant disease) becoming more frequent. During the second group of operations when surgeons had an intermediate level of experience, the risk of major complications decreased (adjusted odds ratio: 0.28, 95% confidence interval: 0.10-0.85), as did the risk of type III complications of Clavien-Dindo classification (adjusted odds ratio 0.15, 95% confidence interval: 0.03-0.93). However, the percent rate of conversion to laparotomy remained stable in the second (intermediate experience) group. In the third group, after the surgeons had performed 150 procedures and when the risk of any type of complication was lowest, the risk of conversion to laparotomy decreased compared to the routine group. CONCLUSIONS: The surgeon's experience in performing laparoscopic hysterectomy plays an essential role in the decrease in the risk of complications, and this finding supports the importance of providing appropriate training for residents and gynecologists to enable them to perform this procedure with an optimal degree of competence and safety.
Asunto(s)
Competencia Clínica , Histerectomía/estadística & datos numéricos , Complicaciones Intraoperatorias , Laparoscopía/estadística & datos numéricos , Laparotomía/estadística & datos numéricos , Curva de Aprendizaje , Cirujanos/estadística & datos numéricos , Adulto , Anciano , Femenino , Humanos , Persona de Mediana Edad , Cirujanos/normasRESUMEN
El síndrome del folículo vacío es una situación en la cual, repetidamente, no se recuperan ovocitos durante la punción-aspiración folicular. Existen 2 tipos de síndrome del folículo vacío: el falso y el genuino. Se presenta el caso clínico de una paciente de 38 años con esterilidad primaria de un año de evolución. Ante un estudio básico de esterilidad normal, se realizaron 4 ciclos de IAC, que resultaron fallidos. Se decidió realizar FIV-ICSI, llevándose a cabo un total de 3 ciclos; el primero, protocolo de estimulación con análogo largo, y los ciclos restantes, protocolo de estimulación con antagonista. En todos los casos se constató la ausencia de errores en la medicación y unos niveles de gonadotropina coriónica humana óptimos. Se llega al diagnóstico de síndrome del folículo vacío genuino, pues a pesar de obtener un desarrollo folicular y niveles adecuados de gonadotropina coriónica humana prepunción, no se obtienen ovocitos durante la misma. La ovodonación actualmente es la mejor alternativa
Empty follicle syndrome is a situation in which there is repeated failure to retrieve oocytes during follicular puncture-aspiration. There are 2 types of empty follicle syndrome: false and genuine. We report the case of a 38-year-old woman with a one-year history of primary sterility. After basic study of normal sterility, the patient underwent 4 unsuccessful artificial insemination cycles. We decided to carry out IVF-ICSI, and the patient underwent a total of 3 cycles. A long-agonist protocol was used in the first stimulation and an antagonist protocol in the remaining 2. In all stimulations, we confirmed the absence of medication errors and optimal levels of human chorionic gonadotropin. A diagnosis of genuine empty follicle syndrome was made because no oocytes were obtained during aspiration despite obtaining follicular development and appropriate levels of human chorionic gonadotropin pre-puncture. Oocyte donation is currently the best alternative
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Humanos , Femenino , Adulto , Infertilidad Femenina/etiología , Recuperación del Oocito/métodos , Técnicas de Maduración In Vitro de los Oocitos , Fertilización In Vitro , Gonadotropina Coriónica/análisis , Donación de OocitoRESUMEN
Endometrial cancer is diagnosed increasingly in young women who wish to have children, and treatments intended to preserve fertility in these patients are becoming more common. The authors describe two women with endometrial cancer who were diagnosed and treated at our center and who needed assisted human reproductive technology, and review current knowledge based on similar cases.
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Neoplasias Endometriales/fisiopatología , Preservación de la Fertilidad , Adulto , Neoplasias Endometriales/terapia , Femenino , HumanosRESUMEN
Objetivo: Comparar la frecuencia de efectos perinatales adversos en función de 3 criterios diagnósticos de diabetes gestacional (DG). Material y métodos: Estudio prospectivo. Las gestantes se clasificaron en 3 categorías: DG según los criterios del NDDG (tratadas), criterios de Carpenter y Coustan e Hyperglycemia and Adverse Pregnancy Outcomes (no tratadas). Se comparó el riesgo de recién nacidos prematuros, macrosomías, grandes para edad gestacional y el tipo de parto entre los grupos. Resultados: Las gestantes con DG presentan mayor frecuencia de resultados perinatales adversos. Las gestantes con criterios Hyperglycemia and Adverse Pregnancy Outcomes no se diferencian significativamente de la población no diabética, mientras que aquellas con criterios de Carpenter y Coustan muestran mayor riesgo de macrosomías y grandes para edad gestacional; OR de 7,14 (1,76-29,96) y 5,84 (1,75-19,52) respectivamente. Sin embargo, no se encuentran diferencias en otras variables obstétricas como la prematuridad o el tipo de parto
Objective: To compare the frequency of adverse perinatal effects according to 3 diagnostic criteria for gestational diabetes (GD). Material and methods: We conducted a prospective study in which pregnant women were categorized according to the following criteria: NDDG (treated), Carpenter-Coustan and Hyperglycemia and Adverse Pregnancy Outcomes (untreated). We compared the risk of preterm infants, fetal macrosomia, large for gestational age infants and type of delivery among the study groups. Results: Women with GD showed a higher frequency of adverse perinatal outcomes. Women with Hyperglycemia and Adverse Pregnancy Outcomes criteria showed no significant difference with non-diabetics. Women with Carpenter-Coustan criteria showed an increased frequency of fetal macrosomia and large for gestational age infants, OR 7.14 (1.76-29.96) and 5.84 (1.75-19.52), respectively. There were no differences among the study groups in other obstetric variables such as prematurity or type of delivery
Asunto(s)
Femenino , Humanos , Embarazo , Diabetes Gestacional/diagnóstico , Macrosomía Fetal/diagnóstico , Estudios Prospectivos , Peso al Nacer , Factores de RiesgoRESUMEN
Objetivo: Determinar la incidencia de abandono y reducción del hábito tabáquico durante la gestación, así como los factores asociados con ésta. Métodos: Estudio retrospectivo de una cohorte de445 embarazadas sanas, fumadoras al inicio del embarazo, atendidas en el Hospital Materno-Infantil Virgen de las Nieves de Granada. Se recogió información acerca del consumo de tabaco, antecedentes obstétricos y variables sociodemográficas. Para el análisis de los datos se utilizaron modelos de regresiónmúltiple. Resultados: El 51,5% de las fumadoras continuó fumando durante el embarazo. La frecuencia de abandono fue menor en mujeres que fumaban más de1 paquete al día (odds ratio [OR] = 0,02, intervalo de confianza [IC] del 95%, 0,01-0,04) y en las mujeres con 1 hijo (OR = 0,49; IC del 95%, 0,28-0,86) o más hijos anteriores (OR = 0,34; IC del 95%, 0,16-0,73).Conclusión: Es posible identificar grupos de embarazadas con menor probabilidad de abandono o reducción del hábito tabáquico en las que se deberían intensificar las estrategias de intervención en este sentido (AU)
Objective: To determine the incidence of smoking cessation and reduced smoking during pregnancy and to identify associated factors. Methods: A cohort of 445 healthy, pregnant women smokers at the beginning of their pregnancies and followed-up at the maternity hospital Virgen de las Nieves(Granada, Spain) was retrospectively studied. Data on their use of tobacco and alcohol before and during pregnancy, as well as obstetric and sociodemographic variables, were collected. Data were evaluated through multiple regression models. Results: A total of 51.5% of all women smoking at the beginning of pregnancy continued to smoke. Smoking cessation was lower among women who smoked more than on pack per day before conceiving (OR =0.02; 95% CI, 0.01-0.04) and in those with one previous child (OR = 0.49; 95% CI, 0.28-0.86) or more(OR = 0.34; 95% CI, 0.16-0.73).Conclusion: Groups of expectant mothers with a lower probability of smoking cessation or reduction can be identified. In these women, intervention strategies should be intensified (AU)