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1.
Sensors (Basel) ; 23(13)2023 Jul 02.
Artículo en Inglés | MEDLINE | ID: mdl-37447939

RESUMEN

A new artificial intelligence-based approach is proposed by developing a deep learning (DL) model for identifying the people who violate the face mask protocol in public places. To achieve this goal, a private dataset was created, including different face images with and without masks. The proposed model was trained to detect face masks from real-time surveillance videos. The proposed face mask detection (FMDNet) model achieved a promising detection of 99.0% in terms of accuracy for identifying violations (no face mask) in public places. The model presented a better detection capability compared to other recent DL models such as FSA-Net, MobileNet V2, and ResNet by 24.03%, 5.0%, and 24.10%, respectively. Meanwhile, the model is lightweight and had a confidence score of 99.0% in a resource-constrained environment. The model can perform the detection task in real-time environments at 41.72 frames per second (FPS). Thus, the developed model can be applicable and useful for governments to maintain the rules of the SOP protocol.


Asunto(s)
COVID-19 , Máscaras , Humanos , Inteligencia Artificial , Pandemias , Equipo de Protección Personal
2.
Biomed Res Int ; 2023: 8726320, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37152587

RESUMEN

Background: Table olives are becoming well recognized as a source of probiotic bacteria that might be used to create a health-promoting fermented food product by traditional procedures based on the activities of indigenous microbial consortia present in local environments. Methodology. In the present study, the characterization of probiotic bacteria isolated from mince, chunks, and brine of fermented green and black olives (Olea europaea) was done based on morphological, biochemical, and physiological characteristics. Results: Bacterial isolates demonstrated excellent survival abilities at 25, 37, and 45°C and at a variable range of pH. However, the optimum temperature is 37 and the optimum pH is 7 for all three isolates. An antimicrobial susceptibility pattern was found among these isolates through the disc diffusion method. Most of the isolates were susceptible to streptomycin, imipenem, and chloramphenicol, whereas, amoxicillin showed resistance to these isolates, and variable results were recorded for the rest of the antibiotics tested. The growth of the isolates was optimum with the supplementation of 3% NaCl and 0.3% bile salt. The isolated bacteria were able to ferment skimmed milk into yogurt, hence making it capable of producing organic acid. Conclusion: Isolates of Lactobacillus crispatus MB417, Lactococcus lactis MB418 from black olives, and Carnobacterium divergens MB421 from green olives were characterized as potential candidates for use as starter cultures to induce fermentation of other probiotic food products.


Asunto(s)
Lactobacillus crispatus , Lactococcus lactis , Olea , Probióticos , Bacterias , Probióticos/farmacología , Fermentación , Microbiología de Alimentos
3.
Diagnostics (Basel) ; 13(6)2023 Mar 14.
Artículo en Inglés | MEDLINE | ID: mdl-36980412

RESUMEN

Melanoma, a kind of skin cancer that is very risky, is distinguished by uncontrolled cell multiplication. Melanoma detection is of the utmost significance in clinical practice because of the atypical border structure and the numerous types of tissue it can involve. The identification of melanoma is still a challenging process for color images, despite the fact that numerous approaches have been proposed in the research that has been done. In this research, we present a comprehensive system for the efficient and precise classification of skin lesions. The framework includes preprocessing, segmentation, feature extraction, and classification modules. Preprocessing with DullRazor eliminates skin-imaging hair artifacts. Next, Fully Connected Neural Network (FCNN) semantic segmentation extracts precise and obvious Regions of Interest (ROIs). We then extract relevant skin image features from ROIs using an enhanced Sobel Directional Pattern (SDP). For skin image analysis, Sobel Directional Pattern outperforms ABCD. Finally, a stacked Restricted Boltzmann Machine (RBM) classifies skin ROIs. Stacked RBMs accurately classify skin melanoma. The experiments have been conducted on five datasets: Pedro Hispano Hospital (PH2), International Skin Imaging Collaboration (ISIC 2016), ISIC 2017, Dermnet, and DermIS, and achieved an accuracy of 99.8%, 96.5%, 95.5%, 87.9%, and 97.6%, respectively. The results show that a stack of Restricted Boltzmann Machines is superior for categorizing skin cancer types using the proposed innovative SDP.

4.
J Adv Res ; 48: 191-211, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-36084812

RESUMEN

INTRODUCTION: Pneumonia is a microorganism infection that causes chronic inflammation of the human lung cells. Chest X-ray imaging is the most well-known screening approach used for detecting pneumonia in the early stages. While chest-Xray images are mostly blurry with low illumination, a strong feature extraction approach is required for promising identification performance. OBJECTIVES: A new hybrid explainable deep learning framework is proposed for accurate pneumonia disease identification using chest X-ray images. METHODS: The proposed hybrid workflow is developed by fusing the capabilities of both ensemble convolutional networks and the Transformer Encoder mechanism. The ensemble learning backbone is used to extract strong features from the raw input X-ray images in two different scenarios: ensemble A (i.e., DenseNet201, VGG16, and GoogleNet) and ensemble B (i.e., DenseNet201, InceptionResNetV2, and Xception). Whereas, the Transformer Encoder is built based on the self-attention mechanism with multilayer perceptron (MLP) for accurate disease identification. The visual explainable saliency maps are derived to emphasize the crucial predicted regions on the input X-ray images. The end-to-end training process of the proposed deep learning models over all scenarios is performed for binary and multi-class classification scenarios. RESULTS: The proposed hybrid deep learning model recorded 99.21% classification performance in terms of overall accuracy and F1-score for the binary classification task, while it achieved 98.19% accuracy and 97.29% F1-score for multi-classification task. For the ensemble binary identification scenario, ensemble A recorded 97.22% accuracy and 97.14% F1-score, while ensemble B achieved 96.44% for both accuracy and F1-score. For the ensemble multiclass identification scenario, ensemble A recorded 97.2% accuracy and 95.8% F1-score, while ensemble B recorded 96.4% accuracy and 94.9% F1-score. CONCLUSION: The proposed hybrid deep learning framework could provide promising and encouraging explainable identification performance comparing with the individual, ensemble models, or even the latest AI models in the literature. The code is available here: https://github.com/chiagoziemchima/Pneumonia_Identificaton.


Asunto(s)
Neumonía , Humanos , Rayos X , Neumonía/diagnóstico por imagen , Inflamación , Tórax , Suministros de Energía Eléctrica
5.
Curr Pharm Des ; 28(45): 3618-3636, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36464881

RESUMEN

Insomnia is well-known as trouble in sleeping and enormously influences human life due to the shortage of sleep. Reactive Oxygen Species (ROS) accrue in neurons during the waking state, and sleep has a defensive role against oxidative damage and dissipates ROS in the brain. In contrast, insomnia is the source of inequity between ROS generation and removal by an endogenous antioxidant defense system. The relationship between insomnia, depression, and anxiety disorders damages the cardiovascular systems' immune mechanisms and functions. Traditionally, polysomnography is used in the diagnosis of insomnia. This technique is complex, with a long time overhead. In this work, we have proposed a novel machine learning-based automatic detection system using the R-R intervals extracted from a single-lead electrocardiograph (ECG). Additionally, we aimed to explore the role of oxidative stress and inflammation in sleeping disorders and cardiovascular diseases, antioxidants' effects, and the psychopharmacological effect of herbal medicine. This work has been carried out in steps, which include collecting the ECG signal for normal and insomnia subjects, analyzing the signal, and finally, automatic classification. We used two approaches, including subjects (normal and insomnia), two sleep stages, i.e., wake and rapid eye movement, and three Machine Learning (ML)-based classifiers to complete the classification. A total number of 3000 ECG segments were collected from 18 subjects. Furthermore, using the theranostics approach, the role of mitochondrial dysfunction causing oxidative stress and inflammatory response in insomnia and cardiovascular diseases was explored. The data from various databases on the mechanism of action of different herbal medicines in insomnia and cardiovascular diseases with antioxidant and antidepressant activities were also retrieved. Random Forest (RF) classifier has shown the highest accuracy (subjects: 87.10% and sleep stage: 88.30%) compared to the Decision Tree (DT) and Support Vector Machine (SVM). The results revealed that the suggested method could perform well in classifying the subjects and sleep stages. Additionally, a random forest machine learning-based classifier could be helpful in the clinical discovery of sleep complications, including insomnia. The evidence retrieved from the databases showed that herbal medicine contains numerous phytochemical bioactives and has multimodal cellular mechanisms of action, viz., antioxidant, anti-inflammatory, vasorelaxant, detoxifier, antidepressant, anxiolytic, and cell-rejuvenator properties. Other herbal medicines have a GABA-A receptor agonist effect. Hence, we recommend that the theranostics approach has potential and can be adopted for future research to improve the quality of life of humans.


Asunto(s)
Enfermedades Cardiovasculares , Trastornos del Inicio y del Mantenimiento del Sueño , Trastornos del Sueño-Vigilia , Humanos , Trastornos del Inicio y del Mantenimiento del Sueño/tratamiento farmacológico , Antioxidantes/farmacología , Antioxidantes/uso terapéutico , Enfermedades Cardiovasculares/tratamiento farmacológico , Calidad de Vida , Especies Reactivas de Oxígeno , Sueño , Inflamación/tratamiento farmacológico , Estrés Oxidativo , Antiinflamatorios , Aprendizaje Automático , Extractos Vegetales/farmacología , Extractos Vegetales/uso terapéutico , Máquina de Vectores de Soporte
6.
Bioengineering (Basel) ; 9(11)2022 Nov 18.
Artículo en Inglés | MEDLINE | ID: mdl-36421110

RESUMEN

According to research, classifiers and detectors are less accurate when images are blurry, have low contrast, or have other flaws which raise questions about the machine learning model's ability to recognize items effectively. The chest X-ray image has proven to be the preferred image modality for medical imaging as it contains more information about a patient. Its interpretation is quite difficult, nevertheless. The goal of this research is to construct a reliable deep-learning model capable of producing high classification accuracy on chest x-ray images for lung diseases. To enable a thorough study of the chest X-ray image, the suggested framework first derived richer features using an ensemble technique, then a global second-order pooling is applied to further derive higher global features of the images. Furthermore, the images are then separated into patches and position embedding before analyzing the patches individually via a vision transformer approach. The proposed model yielded 96.01% sensitivity, 96.20% precision, and 98.00% accuracy for the COVID-19 Radiography Dataset while achieving 97.84% accuracy, 96.76% sensitivity and 96.80% precision, for the Covid-ChestX-ray-15k dataset. The experimental findings reveal that the presented models outperform traditional deep learning models and other state-of-the-art approaches provided in the literature.

7.
Diagnostics (Basel) ; 12(11)2022 Nov 16.
Artículo en Inglés | MEDLINE | ID: mdl-36428875

RESUMEN

Blood cells carry important information that can be used to represent a person's current state of health. The identification of different types of blood cells in a timely and precise manner is essential to cutting the infection risks that people face on a daily basis. The BCNet is an artificial intelligence (AI)-based deep learning (DL) framework that was proposed based on the capability of transfer learning with a convolutional neural network to rapidly and automatically identify the blood cells in an eight-class identification scenario: Basophil, Eosinophil, Erythroblast, Immature Granulocytes, Lymphocyte, Monocyte, Neutrophil, and Platelet. For the purpose of establishing the dependability and viability of BCNet, exhaustive experiments consisting of five-fold cross-validation tests are carried out. Using the transfer learning strategy, we conducted in-depth comprehensive experiments on the proposed BCNet's architecture and test it with three optimizers of ADAM, RMSprop (RMSP), and stochastic gradient descent (SGD). Meanwhile, the performance of the proposed BCNet is directly compared using the same dataset with the state-of-the-art deep learning models of DensNet, ResNet, Inception, and MobileNet. When employing the different optimizers, the BCNet framework demonstrated better classification performance with ADAM and RMSP optimizers. The best evaluation performance was achieved using the RMSP optimizer in terms of 98.51% accuracy and 96.24% F1-score. Compared with the baseline model, the BCNet clearly improved the prediction accuracy performance 1.94%, 3.33%, and 1.65% using the optimizers of ADAM, RMSP, and SGD, respectively. The proposed BCNet model outperformed the AI models of DenseNet, ResNet, Inception, and MobileNet in terms of the testing time of a single blood cell image by 10.98, 4.26, 2.03, and 0.21 msec. In comparison to the most recent deep learning models, the BCNet model could be able to generate encouraging outcomes. It is essential for the advancement of healthcare facilities to have such a recognition rate improving the detection performance of the blood cells.

8.
Comput Intell Neurosci ; 2022: 9475162, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36210977

RESUMEN

Electrocardiography (ECG) is a well-known noninvasive technique in medical science that provides information about the heart's rhythm and current conditions. Automatic ECG arrhythmia diagnosis relieves doctors' workload and improves diagnosis effectiveness and efficiency. This study proposes an automatic end-to-end 2D CNN (two-dimensional convolution neural networks) deep learning method with an effective DenseNet model for addressing arrhythmias recognition. To begin, the proposed model is trained and evaluated on the 97720 and 141404 beat images extracted from the Massachusetts Institute of Technology-Beth Israel Hospital (MIT-BIH) arrhythmia and St. Petersburg Institute of Cardiological Technics (INCART) datasets (both are imbalanced class datasets) using a stratified 5-fold evaluation strategy. The data is classified into four groups: N (normal), V (ventricular ectopic), S (supraventricular ectopic), and F (fusion), based on the Association for the Advancement of Medical Instrumentation® (AAMI). The experimental results show that the proposed model outperforms state-of-the-art models for recognizing arrhythmias, with the accuracy of 99.80% and 99.63%, precision of 98.34% and 98.94%, and F 1-score of 98.91% and 98.91% on the MIT-BIH arrhythmia and INCART datasets, respectively. Using a transfer learning mechanism, the proposed model is also evaluated with only five individuals of supraventricular MIT-BIH arrhythmia and five individuals of European ST-T datasets (both of which are also class imbalanced) and achieved satisfactory results. So, the proposed model is more generalized and could be a prosperous solution for arrhythmias recognition from class imbalance datasets in real-life applications.


Asunto(s)
Arritmias Cardíacas , Electrocardiografía , Algoritmos , Arritmias Cardíacas/diagnóstico , Bases de Datos Factuales , Electrocardiografía/métodos , Frecuencia Cardíaca , Humanos , Redes Neurales de la Computación , Procesamiento de Señales Asistido por Computador
9.
Oxid Med Cell Longev ; 2022: 3599246, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35873799

RESUMEN

Premenstrual syndrome (PMS) significantly lowers the quality of life and impairs personal and social relationships in reproductive-age women. Some recommendations are that inappropriate oxidative stress and inflammatory response are involved in PMS. Various nutritional supplements and herbs showed neuro-psycho-pharmacological activity with antioxidant and anti-inflammatory properties. This study aims to determine the systematic review of randomized controlled trials (RCTs) of herbal medicine and nutritional supplements in PMS. We also comprehensively highlighted the role of oxidative stress, inflammation, and mitochondrial changes on PMS with the application of computational intelligence. We used PRISMA and research question-based techniques to collect the data for evaluation of our study on different databases such as Scopus, PubMed, and PROSPERO from 1990 to 2022. The methodological quality of the published study was assessed by the modified Jadad scale. In addition, we used network visualization and word cloud techniques to find the closest terms of the study based on previous publications. While we also used computational intelligence techniques to give the idea for the classification of experimental data from PMS. We found 25 randomized controlled studies with 1949 participants (mean ± SD: 77.96 ± 22.753) using the PRISMA technique, and all were high-quality studies. We also extracted the closest terms related to our study using network visualization techniques. This work has revealed the future direction and research gap on the role of oxidative stress and inflammation in PMS. In vitro and in vivo studies showed that bioactive molecules such as curcumin, allicin, anethole, thymoquinone, cyanidin 3-glucoside, gamma-linoleic acid, and various molecules not only have antioxidant and anti-inflammatory properties but also other various activities such as GABA-A receptor agonist, serotonergic, antidepressant, sedative, and analgesic. Traditional Unani Herbal medicine and nutritional supplements can effectively relieve PMS symptoms as they possess many bioactive molecules that are pharmacologically proven for the aforementioned properties. Hence, these biomolecules might influence a complex physical and psychological disease process like PMS. However, more rigorous research studies are recommended for in-depth knowledge of the efficacy of bioactive molecules on premenstrual syndrome in clinical trials.


Asunto(s)
Antioxidantes , Síndrome Premenstrual , Antiinflamatorios/farmacología , Antiinflamatorios/uso terapéutico , Antioxidantes/farmacología , Antioxidantes/uso terapéutico , Síntomas Conductuales , Femenino , Humanos , Inflamación/tratamiento farmacológico , Estrés Oxidativo , Síndrome Premenstrual/tratamiento farmacológico
10.
Biosensors (Basel) ; 12(6)2022 Jun 17.
Artículo en Inglés | MEDLINE | ID: mdl-35735574

RESUMEN

In the modern world, wearable smart devices are continuously used to monitor people's health. This study aims to develop an automatic mental stress detection system for researchers based on Electrocardiogram (ECG) signals from smart T-shirts using machine learning classifiers. We used 20 subjects, including 10 from mental stress (after twelve hours of continuous work in the laboratory) and 10 from normal (after completing the sleep or without any work). We also applied three scoring techniques: Chalder Fatigue Scale (CFS), Specific Fatigue Scale (SFS), Depression, Anxiety, and Stress Scale (DASS), to confirm the mental stress. The total duration of ECG recording was 1800 min, including 1200 min during mental stress and 600 min during normal. We calculated two types of features, such as demographic and extracted by ECG signal. In addition, we used Decision Tree (DT), Naive Bayes (NB), Random Forest (RF), and Logistic Regression (LR) to classify the intra-subject (mental stress and normal) and inter-subject classification. The DT leave-one-out model has better performance in terms of recall (93.30%), specificity (96.70%), precision (94.40%), accuracy (93.30%), and F1 (93.50%) in the intra-subject classification. Additionally, The classification accuracy of the system in classifying inter-subjects is 94.10% when using a DT classifier. However, our findings suggest that the wearable smart T-shirt based on the DT classifier may be used in big data applications and health monitoring. Mental stress can lead to mitochondrial dysfunction, oxidative stress, blood pressure, cardiovascular disease, and various health problems. Therefore, real-time ECG signals help assess cardiovascular and related risk factors in the initial stage based on machine learning techniques.


Asunto(s)
Electrocardiografía , Dispositivos Electrónicos Vestibles , Teorema de Bayes , Electrodos , Electrónica , Fatiga , Humanos , Aprendizaje Automático
11.
J Healthc Eng ; 2022: 3408501, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35449862

RESUMEN

Recently, cardiac arrhythmia recognition from electrocardiography (ECG) with deep learning approaches is becoming popular in clinical diagnosis systems due to its good prognosis findings, where expert data preprocessing and feature engineering are not usually required. But a lightweight and effective deep model is highly demanded to face the challenges of deploying the model in real-life applications and diagnosis accurately. In this work, two effective and lightweight deep learning models named Deep-SR and Deep-NSR are proposed to recognize ECG beats, which are based on two-dimensional convolution neural networks (2D CNNs) while using different structural regularizations. First, 97720 ECG beats extracted from all records of a benchmark MIT-BIH arrhythmia dataset have been transformed into 2D RGB (red, green, and blue) images that act as the inputs to the proposed 2D CNN models. Then, the optimization of the proposed models is performed through the proper initialization of model layers, on-the-fly augmentation, regularization techniques, Adam optimizer, and weighted random sampler. Finally, the performance of the proposed models is evaluated by a stratified 5-fold cross-validation strategy along with callback features. The obtained overall accuracy of recognizing normal beat and three arrhythmias (V-ventricular ectopic, S-supraventricular ectopic, and F-fusion) based on the Association for the Advancement of Medical Instrumentation (AAMI) is 99.93%, and 99.96% for the proposed Deep-SR model and Deep-NSR model, which demonstrate that the effectiveness of the proposed models has surpassed the state-of-the-art models and also expresses the higher model generalization. The received results with model size suggest that the proposed CNN models especially Deep-NSR could be more useful in wearable devices such as medical vests, bracelets for long-term monitoring of cardiac conditions, and in telemedicine to accurate diagnose the arrhythmia from ECG automatically. As a result, medical costs of patients and work pressure on physicians in medicals and clinics would be reduced effectively.


Asunto(s)
Algoritmos , Complejos Prematuros Ventriculares , Electrocardiografía , Frecuencia Cardíaca , Humanos , Redes Neurales de la Computación , Procesamiento de Señales Asistido por Computador
12.
Comput Intell Neurosci ; 2022: 7937667, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35378816

RESUMEN

Social media networking is a prominent topic in real life, particularly at the current moment. The impact of comments has been investigated in several studies. Twitter, Facebook, and Instagram are just a few of the social media networks that are used to broadcast different news worldwide. In this paper, a comprehensive AI-based study is presented to automatically detect the Arabic text misogyny and sarcasm in binary and multiclass scenarios. The key of the proposed AI approach is to distinguish various topics of misogyny and sarcasm from Arabic tweets in social media networks. A comprehensive study is achieved for detecting both misogyny and sarcasm via adopting seven state-of-the-art NLP classifiers: ARABERT, PAC, LRC, RFC, LSVC, DTC, and KNNC. To fine tune, validate, and evaluate all of these techniques, two Arabic tweets datasets (i.e., misogyny and Abu Farah datasets) are used. For the experimental study, two scenarios are proposed for each case study (misogyny or sarcasm): binary and multiclass problems. For misogyny detection, the best accuracy is achieved using the AraBERT classifier with 91.0% for binary classification scenario and 89.0% for the multiclass scenario. For sarcasm detection, the best accuracy is achieved using the AraBERT as well with 88% for binary classification scenario and 77.0% for the multiclass scenario. The proposed method appears to be effective in detecting misogyny and sarcasm in social media platforms with suggesting AraBERT as a superior state-of-the-art deep learning classifier.


Asunto(s)
Inteligencia Artificial , Medios de Comunicación Sociales , Humanos , Red Social
13.
Comput Math Methods Med ; 2022: 4593330, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35069782

RESUMEN

Drosophila melanogaster is an important genetic model organism used extensively in medical and biological studies. About 61% of known human genes have a recognizable match with the genetic code of Drosophila flies, and 50% of fly protein sequences have mammalian analogues. Recently, several investigations have been conducted in Drosophila to study the functions of specific genes exist in the central nervous system, heart, liver, and kidney. The outcomes of the research in Drosophila are also used as a unique tool to study human-related diseases. This article presents a novel automated system to classify the gender of Drosophila flies obtained through microscopic images (ventral view). The proposed system takes an image as input and converts it into grayscale illustration to extract the texture features from the image. Then, machine learning (ML) classifiers such as support vector machines (SVM), Naive Bayes (NB), and K-nearest neighbour (KNN) are used to classify the Drosophila as male or female. The proposed model is evaluated using the real microscopic image dataset, and the results show that the accuracy of the KNN is 90%, which is higher than the accuracy of the SVM classifier.


Asunto(s)
Drosophila melanogaster/anatomía & histología , Drosophila melanogaster/clasificación , Aprendizaje Automático , Análisis para Determinación del Sexo/métodos , Animales , Teorema de Bayes , Biología Computacional , Femenino , Procesamiento de Imagen Asistido por Computador/métodos , Procesamiento de Imagen Asistido por Computador/estadística & datos numéricos , Masculino , Microscopía , Análisis para Determinación del Sexo/estadística & datos numéricos , Máquina de Vectores de Soporte
14.
Diagnostics (Basel) ; 13(1)2022 Dec 28.
Artículo en Inglés | MEDLINE | ID: mdl-36611379

RESUMEN

The development of automatic monitoring and diagnosis systems for cardiac patients over the internet has been facilitated by recent advancements in wearable sensor devices from electrocardiographs (ECGs), which need the use of patient-specific approaches. Premature ventricular contraction (PVC) is a common chronic cardiovascular disease that can cause conditions that are potentially fatal. Therefore, for the diagnosis of likely heart failure, precise PVC detection from ECGs is crucial. In the clinical settings, cardiologists typically employ long-term ECGs as a tool to identify PVCs, where a cardiologist must put in a lot of time and effort to appropriately assess the long-term ECGs which is time consuming and cumbersome. By addressing these issues, we have investigated a deep learning method with a pre-trained deep residual network, ResNet-18, to identify PVCs automatically using transfer learning mechanism. Herein, features are extracted by the inner layers of the network automatically compared to hand-crafted feature extraction methods. Transfer learning mechanism handles the difficulties of required large volume of training data for a deep model. The pre-trained model is evaluated on the Massachusetts Institute of Technology-Beth Israel Hospital (MIT-BIH) Arrhythmia and Institute of Cardiological Technics (INCART) datasets. First, we used the Pan-Tompkins algorithm to segment 44,103 normal and 6423 PVC beats, as well as 106,239 normal and 9987 PVC beats from the MIT-BIH Arrhythmia and IN-CART datasets, respectively. The pre-trained model employed the segmented beats as input after being converted into 2D (two-dimensional) images. The method is optimized with the using of weighted random samples, on-the-fly augmentation, Adam optimizer, and call back feature. The results from the proposed method demonstrate the satisfactory findings without the using of any complex pre-processing and feature extraction technique as well as design complexity of model. Using LOSOCV (leave one subject out cross-validation), the received accuracies on MIT-BIH and INCART are 99.93% and 99.77%, respectively, suppressing the state-of-the-art methods for PVC recognition on unseen data. This demonstrates the efficacy and generalizability of the proposed method on the imbalanced datasets. Due to the absence of device-specific (patient-specific) information at the evaluating stage on the target datasets in this study, the method might be used as a general approach to handle the situations in which ECG signals are obtained from different patients utilizing a variety of smart sensor devices.

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