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Background The population's hesitancy to get the coronavirus disease 2019 (COVID-19) vaccination may pose a risk to public health worldwide. However, the causes and contributors to vaccine hesitancy in the Saudi people need to be understood. This study aimed to assess the knowledge and attitudes toward COVID-19 vaccination among the general population in Jeddah, Saudi Arabia. Methodology A cross-sectional study was conducted using an online structured questionnaire titled "Knowledge and attitude toward COVID-19 vaccination." The questionnaire collected demographic characteristics, knowledge, and attitudes toward COVID-19 vaccination among the general population in Jeddah, Saudi Arabia. The questionnaire was distributed through links on various sites, including Twitter and WhatsApp. Results A total of 544 participants were included in the present study. Overall, 64.9% were males, and 35.1% were females. Most of the population had received three doses (83.6%) of the COVID-19 vaccine. About half of the participants had a university education (56.8%), 17.5% of respondents were postgraduates, and 14.2% had secondary education. Overall, 41.4% of the population had a low knowledge level, and 58.5% had a low attitude toward COVID-19 vaccination. Receiving the COVID-19 vaccine was significantly (p < 0.05) associated with the population's knowledge and attitude toward COVID-19 vaccination. In addition, the education level substantially affected the knowledge and attitude toward COVID-19 vaccination. Additionally, knowledge of COVID-19 vaccination had a significant correlation (p < 0.05) with the attitude toward the vaccine. Conclusions Despite the high prevalence of the population who received the three doses of the COVID-19 vaccine in Jeddah city, the study showed insufficient knowledge and attitude among the population toward COVID-19 vaccination. However, fortunately, education plays an essential role in improving the knowledge of COVID-19 vaccination.
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Background On March 11, 2020, the World Health Organization (WHO) proclaimed coronavirus disease 2019 (COVID-19) a pandemic. COVID-19 can result in asymptomatic infection, severe pneumonia, and death. In this study, healthcare workers in Jeddah, Saudi Arabia, were asked to reflect on their knowledge of and attitudes toward the COVID-19 vaccine. Methods Online anonymous polling of healthcare professionals in Jeddah, Saudi Arabia, was done. During the COVID-19 pandemic, the respondents' demographic information and knowledge of and attitudes toward the COVID-19 vaccine were gathered through a questionnaire. Both descriptive and inferential statistics were used to analyze the data. Results The knowledge of the responders for each vaccine is as follows: Pfizer-BioNTech, 96.1%; AstraZeneca-Oxford, 66.1%; Moderna, 56.9%; and Johnson & Johnson's Janssen, 18.2%. A small percentage of responders (5.7%) believe that COVID-19 vaccination may alter their DNA, while 70% believe it can prevent them from getting sick with COVID-19 infection. Half of the responders had a wrong opinion of COVID-19 vaccinations. Conclusion The findings imply that improving healthcare workers' knowledge of vaccines and changing attitudes toward vaccination may increase vaccine acceptability. This would involve addressing the respondents' concerns about vaccine side effects and their general mistrust of vaccine benefits.
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Cytomegalovirus (CMV) can be a reason for severe disease in immunocompromised patients, either via the reactivation of latent CMV infection or via the acquisition of primary CMV infection. Clinical syndromes that may be observed are retinitis, colitis, esophagitis, encephalitis, pneumonitis, hepatitis, uveitis, and graft rejection following transplantation. The simultaneous occurrence of CMV colitis and retinitis as the initial presentation of human immunodeficiency virus (HIV) infection is extremely rare. We present a case of a 42-year-old male, known to have type 2 diabetes, bronchial asthma, and allergic rhinitis, who presented to the emergency department (ED) with two weeks history of abdominal pain and watery diarrhea four to five times per day sometimes accompanied by small amounts of blood. He also had an on-and-off subjective fever for the last two months prior to presentation, loss of appetite, and weight loss of 13 kg over the last six months. Additionally, he had a history of travel outside Saudi Arabia and unprotected sex. HIV-1 serology (combination antigen/antibody immunoassay) was requested, which came out positive, with a viral load of 323141 copies/mL and decreased CD4+ T lymphocytes (0 cel/µL). CMV polymerase chain reaction (PCR) quantitative was detected and the CMV viral load was 694963 IU/mL. Given the patient's bloody diarrhea with positive CMV and HIV, the gastroenterology team was consulted and they decided to proceed with a colonoscopy and biopsy. The patient was diagnosed with CMV colitis based on the biopsy results. The patient also was found to have CMV retinitis based on ophthalmologic assessment. Multidisciplinary teams, including infectious diseases, gastroenterology, ophthalmology, and pathology, should cooperate to facilitate an accurate and fast diagnosis. Further complications can be prevented by early diagnosis andtreatment.
