[Influence of multimodal effect of cytoflavin in the acute brain stroke in patients with metabolic syndrome]. / Mul'timodal'noe deistvie tsitoflavina pri ostrom mozgovom insul'te, razvivshemsya na fone metabolicheskogo sindroma.

We present the results of a multicenter study on efficacy of cytoflavin in the treatment of patients with acute ischemic stroke. One hundred and twenty patients (60 of main group and 60 of control group) were enrolled in the study. All patients received basic therapy aimed at to improve systemic hemodynamics. Rheological blood properties and to prevent stroke complications. Patients of main group were treated with cytoflavin as follows: 1-10 days -20 ml (in200 ml of 0.9% NaCl solution) twice a day intravenously in groups: 11-35 days -850 mg twice a day. We assessed dynamics of restoration of lost functions (NIHSS, Rankin scale, Barthel index) and volume of ischemic lesion (KT, diffusion-weighted image). We reveled a trend towards effect of cytoflavin on the preservations of brain mater in acute phase of stroke. Cytoflavin reduced neurological deficit and improved activities of daily living in patients that may be explained by less brain damage.

[Ultrasonography in the diagnosis of cerebrovascular disorders in pregnancy complicated by gestosis]. / Dopplerografiia v diagnostike nekotorykh tserebrovaskuliarnykh narushenii pri gestoze.

The condition was studied of cerebral hemodynamics in physiological pregnancy and in that complicated by gestosis. A dopplerographic investigation was conducted in 53 pregnant women presenting with varying degree gestosis. The group of comparison was healthy non-pregnant women and those femal subjects presenting with a physiological course of pregnancy. Those female patients presenting with gestosis demonstrate a marked increase in the peripheral vascular resistance as compared to healthy subjects and gravids running a physiological course of pregnancy. The degree of identified disturbences has been found to be clearly related to the degree of severity of gestosis. In mild forms, the bloodflow disturbenced are identifiable predominantly in the internal carotid artery.