Probing neurodynamics of experienced emotions-a Hitchhiker's guide to film fMRI.

Film functional magnetic resonance imaging (fMRI) has gained tremendous popularity in many areas of neuroscience. However, affective neuroscience remains somewhat behind in embracing this approach, even though films lend themselves to study how brain function gives rise to complex, dynamic and multivariate emotions. Here, we discuss the unique capabilities of film fMRI for emotion research, while providing a general guide of conducting such research. We first give a brief overview of emotion theories as these inform important design choices. Next, we discuss films as experimental paradigms for emotion elicitation and address the process of annotating them. We then situate film fMRI in the context of other fMRI approaches, and present an overview of results from extant studies so far with regard to advantages of film fMRI. We also give an overview of state-of-the-art analysis techniques including methods that probe neurodynamics. Finally, we convey limitations of using film fMRI to study emotion. In sum, this review offers a practitioners' guide to the emerging field of film fMRI and underscores how it can advance affective neuroscience.

Multimodal Remote Home Monitoring of Lung Transplant Recipients during COVID-19 Vaccinations: Usability Pilot Study of the COVIDA Desk Incorporating Wearable Devices.

Background and Objectives: Remote patient monitoring (RPM) of vital signs and symptoms for lung transplant recipients (LTRs) has become increasingly relevant in many situations. Nevertheless, RPM research integrating multisensory home monitoring in LTRs is scarce. We developed a novel multisensory home monitoring device and tested it in the context of COVID-19 vaccinations. We hypothesize that multisensory RPM and smartphone-based questionnaire feedback on signs and symptoms will be well accepted among LTRs. To assess the usability and acceptability of a remote monitoring system consisting of wearable devices, including home spirometry and a smartphone-based questionnaire application for symptom and vital sign monitoring using wearable devices, during the first and second SARS-CoV-2 vaccination. Materials and Methods: Observational usability pilot study for six weeks of home monitoring with the COVIDA Desk for LTRs. During the first week after the vaccination, intensive monitoring was performed by recording data on physical activity, spirometry, temperature, pulse oximetry and self-reported symptoms, signs and additional measurements. During the subsequent days, the number of monitoring assessments was reduced. LTRs reported on their perceptions of the usability of the monitoring device through a purpose-designed questionnaire. Results: Ten LTRs planning to receive the first COVID-19 vaccinations were recruited. For the intensive monitoring study phase, LTRs recorded symptoms, signs and additional measurements. The most frequent adverse events reported were local pain, fatigue, sleep disturbance and headache. The duration of these symptoms was 5-8 days post-vaccination. Adherence to the main monitoring devices was high. LTRs rated usability as high. The majority were willing to continue monitoring. Conclusions: The COVIDA Desk showed favorable technical performance and was well accepted by the LTRs during the vaccination phase of the pandemic. The feasibility of the RPM system deployment was proven by the rapid recruitment uptake, technical performance (i.e., low number of errors), favorable user experience questionnaires and detailed individual user feedback.

Trimodal prediction of speaking and listening willingness to help improve turn-changing modeling.

Participants in a conversation must carefully monitor the turn-management (speaking and listening) willingness of other conversational partners and adjust their turn-changing behaviors accordingly to have smooth conversation. Many studies have focused on developing actual turn-changing (i.e., next speaker or end-of-turn) models that can predict whether turn-keeping or turn-changing will occur. Participants' verbal and non-verbal behaviors have been used as input features for predictive models. To the best of our knowledge, these studies only model the relationship between participant behavior and turn-changing. Thus, there is no model that takes into account participants' willingness to acquire a turn (turn-management willingness). In this paper, we address the challenge of building such models to predict the willingness of both speakers and listeners. Firstly, we find that dissonance exists between willingness and actual turn-changing. Secondly, we propose predictive models that are based on trimodal inputs, including acoustic, linguistic, and visual cues distilled from conversations. Additionally, we study the impact of modeling willingness to help improve the task of turn-changing prediction. To do so, we introduce a dyadic conversation corpus with annotated scores of speaker/listener turn-management willingness. Our results show that using all three modalities (i.e., acoustic, linguistic, and visual cues) of the speaker and listener is critically important for predicting turn-management willingness. Furthermore, explicitly adding willingness as a prediction task improves the performance of turn-changing prediction. Moreover, turn-management willingness prediction becomes more accurate when this joint prediction of turn-management willingness and turn-changing is performed by using multi-task learning techniques.

Depression Severity Assessment for Adolescents at High Risk of Mental Disorders.

Recent progress in artificial intelligence has led to the development of automatic behavioral marker recognition, such as facial and vocal expressions. Those automatic tools have enormous potential to support mental health assessment, clinical decision making, and treatment planning. In this paper, we investigate nonverbal behavioral markers of depression severity assessed during semi-structured medical interviews of adolescent patients. The main goal of our research is two-fold: studying a unique population of adolescents at high risk of mental disorders and differentiating mild depression from moderate or severe depression. We aim to explore computationally inferred facial and vocal behavioral responses elicited by three segments of the semi-structured medical interviews: Distress Assessment Questions, Ubiquitous Questions, and Concept Questions. Our experimental methodology reflects best practise used for analyzing small sample size and unbalanced datasets of unique patients. Our results show a very interesting trend with strongly discriminative behavioral markers from both acoustic and visual modalities. These promising results are likely due to the unique classification task (mild depression vs. moderate and severe depression) and three types of probing questions.