RESUMEN
BACKGROUND: Waist circumference (WC) thresholds derived from western populations continue to be used in sub-Saharan Africa (SSA) despite increasing evidence of ethnic variation in the association between adiposity and cardiometabolic disease and availability of data from African populations. We aimed to derive a SSA-specific optimal WC cut-point for identifying individuals at increased cardiometabolic risk. METHODS: We used individual level cross-sectional data on 24 181 participants aged ⩾15 years from 17 studies conducted between 1990 and 2014 in eight countries in SSA. Receiver operating characteristic curves were used to derive optimal WC cut-points for detecting the presence of at least two components of metabolic syndrome (MS), excluding WC. RESULTS: The optimal WC cut-point was 81.2 cm (95% CI 78.5-83.8 cm) and 81.0 cm (95% CI 79.2-82.8 cm) for men and women, respectively, with comparable accuracy in men and women. Sensitivity was higher in women (64%, 95% CI 63-65) than in men (53%, 95% CI 51-55), and increased with the prevalence of obesity. Having WC above the derived cut-point was associated with a twofold probability of having at least two components of MS (age-adjusted odds ratio 2.6, 95% CI 2.4-2.9, for men and 2.2, 95% CI 2.0-2.3, for women). CONCLUSION: The optimal WC cut-point for identifying men at increased cardiometabolic risk is lower (⩾81.2 cm) than current guidelines (⩾94.0 cm) recommend, and similar to that in women in SSA. Prospective studies are needed to confirm these cut-points based on cardiometabolic outcomes.International Journal of Obesity advance online publication, 31 October 2017; doi:10.1038/ijo.2017.240.
RESUMEN
OBJECTIVE: To assess the distribution of Mass Index (BMI) and the prevalence of obesity at the time of diagnosing diabetes in the primary health care network in Kinshasa, Democratic Republic of Congo (DRC), from 1993 to 1999. METHODOLOGY: A total of 4967 patients with diabetes were classified according to BMI, age at diagnosis (< 30 years versus > or = 30 years), sex and subsequent treatment (insulin treated versus non-insulin treated). WHO criteria were used to define diabetes and obesity. RESULTS: One diabetic patient in 4 was underweight (26.4%). The prevalence of obesity was 8.1%. Undernutrition was more prevalent in male patients aged < 30 years at diagnosis and, in contrast, obesity was more prevalent in patients aged > or = 30 years at diagnosis, especially among women. CONCLUSION: Undernutrition is highly prevalent at the time of diagnosis in young diabetic patients in Kinshasa. The overall prevalence of obesity at diagnosis is relatively low, except in women diagnosed at > or = 30 years of age. Prospective studies are needed in the Democratic Republic of Congo to characterize secular trends of undernutrition and obesity in order to improve preventive and management strategies.
