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1.
Clinical impact of mutated JAK2 allele burden reduction in polycythemia vera and essential thrombocythemia.
Guglielmelli, Paola; Mora, Barbara; Gesullo, Francesca; Mannelli, Francesco; Loscocco, Giuseppe Gaetano; Signori, Leonardo; Pessina, Chiara; Colugnat, Ilaria; Aquila, Raffaela; Balliu, Manjola; Maccari, Chiara; Romagnoli, Simone; Paoli, Chiara; Nacca, Elena; Fagiolo, Lorenzo; Maffioli, Margherita; Barbui, Tiziano; Passamonti, Francesco; Vannucchi, Alessandro M.
Am J Hematol ; 2024 Jun 06.
Article En | MEDLINE | ID: mdl-38841874
2.
Validation and molecular integration of the RR6 model to predict survival after 6 months of therapy with ruxolitinib.
Coltro, Giacomo; Capecchi, Giulio; Maffioli, Margherita; Mannelli, Francesco; Mora, Barbara; Atanasio, Alessandro; Iurlo, Alessandra; Maccari, Chiara; Farina, Mirko; Nacca, Elena; Caramella, Marianna; Signori, Leonardo; Borella, Miriam; Bertù, Lorenza; Esposito, Maria; Guglielmelli, Paola; Passamonti, Francesco; Vannucchi, Alessandro Maria.
Haematologica ; 2024 May 30.
Article En | MEDLINE | ID: mdl-38813708

Not available.

3.
CALR mutation burden in essential thrombocythemia and disease outcome.
Guglielmelli, Paola; Szuber, Natasha; Gangat, Naseema; Capecchi, Giulio; Maccari, Chiara; Harnois, Michaël; Karrar, Omer; Abdelmagid, Maymona; Balliu, Manjola; Nacca, Elena; Atanasio, Alessandro; Sestini, Ilaria; Désilets, Audrey; Loscocco, Giuseppe Gaetano; Rotunno, Giada; Busque, Lambert; Tefferi, Ayalew; Vannucchi, Alessandro Maria.
Blood ; 143(13): 1310-1314, 2024 Mar 28.
Article En | MEDLINE | ID: mdl-38252902

ABSTRACT: Among 281 patients with essential thrombocythemia and calreticulin (CALR) mutation, we found a variant allele frequency of ≥60% to be associated with significantly shortened myelofibrosis-free survival, mostly apparent with CALR type-1 and CALR type-indeterminate mutations.


Primary Myelofibrosis , Thrombocythemia, Essential , Humans , Thrombocythemia, Essential/complications , Calreticulin/genetics , Primary Myelofibrosis/complications , Mutation , Janus Kinase 2/genetics
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