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1.
J Spec Oper Med ; 20(3): 117-119, 2020.
Article En | MEDLINE | ID: mdl-32969015

America's adversaries will contest US military superiority in the domains of land, sea, air, space, and cyberspace. Fundamentally, these foes seek to disrupt the dominance of American fighting forces through anti-access and area denial (A2AD) systems, such as cyber exploitation, electromagnetic jamming, air defense networks, and hypersonic capabilities. According to Training and Doctrine Command (TRADOC) Pamphlet 525- 3-1, these A2AD capabilities create multiple layers of stand-off that inhibit the US ability to focus combat power and achieve strategic objectives in a contested, increasingly lethal, inherently complex, and challenging operational environment.1 The Department of Defense (DoD) plans to mitigate this shift in enemy strategy through the adoption of multidomain operations (MDO).1 MDO is defined as operations that converge capabilities to overcome an adversary's strengths across various domains by imposing simultaneous dilemmas that achieve operational and tactical objectives.1 Within this MDO construct, medical treatment expectations must shift accordingly as the ability to rapidly treat and evacuate patients may be constrained by enemy action. Thus, the notion of prolonged field care (PFC) may be a necessity on the future battlefield. As Special Operations Forces (SOF) continue to refine what PFC entails, it is imperative that an understanding of the incidence and type of diseases that require medical evacuation to higher levels of care be thoughtfully estimated. Armed with an understanding of the anticipated epidemiology, effective prioritization of training requirements and equipment acquisition is possible in a manner that is complementary to the overall success of the assigned mission. Furthermore, this prior planning mitigates risk, as the limitations of money and time impose significant opportunity costs in the short run should the disproportionate mix of disease states be pursued, which in turn, avoids jeopardizing Soldiers' lives over the long term.


Military Medicine , Military Personnel , Humans , Incidence , United States
2.
Colorectal Dis ; 2017 Dec 22.
Article En | MEDLINE | ID: mdl-29271564

We submit a video vignette describing how to perform a video-assistant peri-anal abscess drainage plus insertion of a draining seton. We have been using this technique within the NHS for two years successfully to manage acute perianal abscesses. This article is protected by copyright. All rights reserved.

3.
Pancreas ; 44(2): 260-5, 2015 Mar.
Article En | MEDLINE | ID: mdl-25438071

OBJECTIVES: Individuals from hereditary pancreatitis (HP) and familial pancreatic cancer (FPC) kindreds are at increased risk of developing pancreatic cancer. Premalignant molecular changes may be detected in pancreatic juice collected by endoscopic retrograde cholangiopancreatography (ERCP). The objective was to determine the risk of post-ERCP pancreatitis (PEP). METHODS: A prospective study (1999-2013) was undertaken of 80 ERCPs (24 in HP and 56 in FPC) from 60 individuals and the impact of PEP prophylaxis using a self-expelling pancreatic stent and 50 mg diclofenac per rectum from 2008. RESULTS: There was no PEP in the HP cohort and 13 (23.2%) PEP from 56 procedures in the FPC cohort (P = 0.0077). Up to 2008 PEP had occurred in 7 (43.8%) of 16 procedures in FPC individuals versus none of 18 procedures in HP individuals (P = 0.0021). After the introduction of prophylaxis, the incidence of PEP fell to 6 (15.0%) of 40 procedures in FPC individuals (P = 0.0347).The odds ratio (95% confidence interval) was 0.23 (0.06-0.84) in favor of prophylaxis (0.035). CONCLUSIONS: Individuals with HP are at minimal risk for PEP. Although the risk of PEP in individuals with FPC can be reduced by using prophylactic self-expelling stents and diclofenac, it remains too high for routine screening.


Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Cholangiopancreatography, Endoscopic Retrograde/adverse effects , Diclofenac/administration & dosage , Pancreatic Juice/chemistry , Pancreatic Neoplasms/diagnosis , Pancreatitis, Chronic/diagnosis , Pancreatitis/prevention & control , Stents , Administration, Rectal , Adult , Biomarkers, Tumor/genetics , Female , Genetic Testing , Humans , Incidence , Logistic Models , Male , Middle Aged , Multivariate Analysis , Odds Ratio , Pancreatic Neoplasms/genetics , Pancreatitis/diagnosis , Pancreatitis/epidemiology , Pancreatitis, Chronic/genetics , Predictive Value of Tests , Prospective Studies , Registries , Risk Assessment , Risk Factors , Treatment Outcome , United Kingdom/epidemiology
5.
HPB (Oxford) ; 14(7): 483-6, 2012 Jul.
Article En | MEDLINE | ID: mdl-22672551

BACKGROUND: Endoscopic ultrasonography (EUS)-guided choledochoduodenostomy (CDS) is an alternative to percutaneous transhepatic cholangiography (PTC) drainage in patients with an obstructed biliary system where conventional endoscopic retrograde biliary drainage (ERBD) has been unsuccessful. METHODS: Five EUS-CDS procedures were reviewed to assess whether successful decompression was achieved and maintained. RESULTS: There was technical success in each instance with no immediate complications. There was a significant fall in the median bilirubin of 164 mmol/l. The median follow-up was 44 days. In one patient the stent migrated with no adverse outcome. CONCLUSION: EUS-CDS is a viable alternative to PTC with fewer complications and comparable success rates. EUS-CDS may offer a future route for novel therapeutic advances.


Cholangiopancreatography, Endoscopic Retrograde , Choledochostomy , Cholestasis/surgery , Decompression, Surgical/methods , Duodenostomy , Endosonography , Ultrasonography, Interventional , Aged , Bilirubin/blood , Biomarkers/blood , Cholangiopancreatography, Endoscopic Retrograde/adverse effects , Cholangiopancreatography, Endoscopic Retrograde/instrumentation , Choledochostomy/adverse effects , Choledochostomy/instrumentation , Cholestasis/blood , Cholestasis/diagnostic imaging , Decompression, Surgical/adverse effects , Decompression, Surgical/instrumentation , Duodenostomy/adverse effects , Duodenostomy/instrumentation , England , Female , Humans , Male , Middle Aged , Stents , Time Factors , Treatment Outcome
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