Topical N-acetylcysteine is gaining recognition as a useful and safe therapy for lamellar ichthyosis. We report a case of inherited lamellar ichthyosis that showed a good response to treatment with a new formula of N-acetylcysteine cream. With this new formula, which is described in the article in a practical manner, the odor of sulfur was minimized and we obtained excellent adherence to treatment.
Acetylcysteine/administration & dosage , Chemistry, Pharmaceutical/methods , Ichthyosis, Lamellar/drug therapy , Administration, Topical , Child, Preschool , Free Radical Scavengers/administration & dosage , Humans , Male , Treatment Outcome
Mid-dermal elastolysis is a rare disorder characterised by focal loss of elastic tissue in the mid-dermis. Most patients present with lesions of fine wrinkling (type I) or perifollicular papules (type II). The reticular variant (type III) has been described less often in the literature. We report a case of a young woman with type III mid-dermal elastolysis.
Dermis/pathology , Elastic Tissue/pathology , Skin Diseases/diagnosis , Female , Humans , Middle Aged , Skin Aging/pathology , Skin Diseases/etiology , Skin Diseases/therapy
