[Endothelial dysfunction as a pathogenetic factor of sensorineural hearing loss]. / Endotelial'naya disfunktsiya kak patogeneticheskii faktor sensonevral'noi tugoukhosti.

Chronic sensorineural hearing loss (SNHL) is a common disease that leads to disability of the population. Despite the many reports devoted to SNHL, the question of the pathogenesis of the disease is still open. Many researchers consider the development of SNHL as a manifestation of microangiopathy. The mechanism of development of microangiopathy in SNHL is multifactorial, but most researchers agree that endothelial dysfunction (ED) triggers a complex of pathological changes in the vessels of the inner ear. OBJECTIVE: Review of the results of scientific research in recent years on the problem of etiopathogenesis of sensorineural hearing loss from the perspective of endothelial dysfunction in the formation of auditory disorders.

[Features of intestinal infections in elderly patients.]

The article compares the flow of intestinal infections in elderly and young people. Analyzed the medical records of 172 persons 60-85 years and 82 history persons 20-40 years with salmonellosis, shigellosis and rotavirus gastroenteritis. It is revealed that bacterial intestinal infections, salmonellosis and shigellosis, those over 60 years of age have the clinical differences and flow is heavier than in patients 20-40 years. Clinic of rotaviral gastroenteritis is not age-appropriate. Knowledge of clinic of intestinal infections in persons of elderly and senile age should your doctor for early diagnosis and proper treatment of patients of this category.

[Admixtures present in antitoxic horse sera and pepsin preparations]. / Izuchenie primesei, prisutstvuiushchikh v antitoksicheskikh loshadinykh syvorotkakh i preparatakh pepsina.

Antitoxic therapeutic sera produced by the method "Diaferm-3" (devised at the Institute of Epidemiology and Microbiology of the USSR Academy of Medical Sciences) are contaminated in the process of production with group-specific substances and extraneous enzymes contained in crude preparations of swine pepsin. These ballast substances have a negative influence on the process of purification and the stability of antitoxin during the storage of the sera and constitute one of the reasons of their high reactogenicity.