The role of endoscopic bladder tumour assessment in the management of patients subjected to transurethral bladder tumour resection.

Despite complete resection, non-muscle invasive bladder cancers tend to recur. Therefore, their risk stratification was implemented to select adjuvant therapy. Immediate intravesical chemotherapeutic instillations were shown to decrease the risk of recurrence in those with low-risk disease. The purpose of the study was to determine the role of endoscopic assessment in the management of patients subjected to transurethral resection of the bladder tumour (TURBT). In 262 patients submitted to TURBT due to primary bladder tumour, the size and the number of the lesion(s) were noted and the stage as well as the grade of the tumour(s) were typed. The individual features were then scored according to the European Organisation of Research and Treatment of Cancer 'Bladder Calculator' and the lesions were classified into the low, intermediate and high risk of recurrence group. Clinical evaluation was then compared with pathological report and final triage. Based on the clinical data, 95 (36.25%), 105 (40.07%) and 3 (1.14%) patients were endoscopically assigned to the groups of low, intermediate and high risk of recurrence respectively. After pathological report, correct risk stratification was confirmed in 86 (90.5%), 95 (90.5%) and 3 (100%) patients respectively. Endoscopic assessment of bladder cancers allows to accurately establish the risk of recurrence and may facilitate implementation of adjuvant therapy before histological evaluation.

[Time course of changes in tuberculin responses in children with monotonous tuberculin sensitivity on anti-tuberculous drugs]. / Dinamika tuberkulinovykh reaktsii u detei s monotonnoi tuberkulinovoi chuvstvitel'nost'iu na fone lecheniia protivotuberkuleznymi preparatami.

A group of 64 children with monotonous tuberculin sensitivity was analyzed. Intrathoracic lymph nodal tuberculosis (ITLNT) was revealed in 26 (41%) children. The remaining 38 (59% children with tuberculosis infection received a course of preventive treatment by taking into account the presence of risk factors. After tuberculosis treatment in children with ITLNT and tuberculous infection, papules due to Mantoux test significantly reduced in size.