Association between low level of physical activity and mobility limitation in older adults: evidence from the SABE study.

Several studies are limited by verifying the level of physical activity with questionnaires and not through objective measurement in older adults. This article aims to analyze the association between a low level of physical activity with accelerometry) and mobility limitation in older adults. A population-based cross-sectional study conducted with 543 older adults. Multiple regression analysis was performed using hierarchical analysis, grouping the variables into two blocks ordered according to the precedence with which they acted on the outcomes. Among the evaluated older adults, 13.7% presented mobility limitations and among these 60.39% were in the low level of physical activity group. Older adults with a low level of physical activity (OR = 3.49 [2.0 - 6.13]), aged 75 and over (OR = 1.97 [1.03 - 3.72]), living without a partner (OR = 2.01 [1.09 - 3.68]), having difficulty performing basic (OR = 2.49 [1.45 - 4.28]) and instrumental (OR = 2.28) [1.18 - 4.36]) activities of daily life, and multimorbidity (OR = 2.06 [1.04 - 4.08]) were independently associated with mobility limitation. A low level of physical activity increases the chance of mobility limitation in older adults, regardless of sociodemographic and clinical variables.

Association between low level of physical activity and mobility limitation in older adults: evidence from the SABE study / Associação entre baixo nível de atividade física e limitação de mobilidade em idoso: evidência do estudo SABE

Abstract Several studies are limited by verifying the level of physical activity with questionnaires and not through objective measurement in older adults. This article aims to analyze the association between a low level of physical activity with accelerometry) and mobility limitation in older adults. A population-based cross-sectional study conducted with 543 older adults. Multiple regression analysis was performed using hierarchical analysis, grouping the variables into two blocks ordered according to the precedence with which they acted on the outcomes. Among the evaluated older adults, 13.7% presented mobility limitations and among these 60.39% were in the low level of physical activity group. Older adults with a low level of physical activity (OR = 3.49 [2.0 - 6.13]), aged 75 and over (OR = 1.97 [1.03 - 3.72]), living without a partner (OR = 2.01 [1.09 - 3.68]), having difficulty performing basic (OR = 2.49 [1.45 - 4.28]) and instrumental (OR = 2.28) [1.18 - 4.36]) activities of daily life, and multimorbidity (OR = 2.06 [1.04 - 4.08]) were independently associated with mobility limitation. A low level of physical activity increases the chance of mobility limitation in older adults, regardless of sociodemographic and clinical variables.

Resumo Vários estudos são limitados por meio da verificação do nível de atividade física com questionários, mas não possuem medidas objetivas em adultos mais velhos. O objetivo deste artigo é analisar a associação entre um baixo nível de atividade física e limitação de mobilidade em idosos. Um estudo transversal de base populacional realizado com 543 idosos. A análise múltipla da regressão foi realizada usando a análise hierárquica, agrupando as variáveis em dois blocos ordenados de acordo com a precedência com que atuaram sobre os resultados. Entre os idosos avaliados, 13,7% apresentaram limitações de mobilidade e entre estes 60,39% estavam no baixo nível de atividade física. Idosos com um baixo nível de atividade física (OR = 3,49 [2,0 - 6,13]), com idade igual ou superior a 75 anos (OR = 1,97 [1,03 - 3,72]), vivendo sem parceiro (OR = 2,01 [1,09 - 3,68]), dificuldade de viver sem um parceiro (OR = 2,01 [1,09 - 3,68]), dificuldades com atividades básicas (OR = 2,49 [1,45 - 4,28]) e as atividades instrumentais (OR = 2.28) [1.18 - 4.36]) atividades da vida do dia a dia e multimobilidade (OR = 2,06 [1,04 - 4,08]) foram associadas independentemente à mobilidade. Um baixo nível de atividade física aumenta a possibilidade de limitação da mobilidade em adultos idosos, independentemente das variáveis sociodemográficas e clínicas.

Factors associated with inflamm-aging in institutionalized older people.

The increase in inflammatory cytokines associated with a reduction in the bioavailability of zinc has been used as a marker for inflammation. Despite the high inflammatory state found in institutionalized older individuals, few studies have proposed verifying the factors associated with this condition in this population. To verify the factors associated with inflamm-aging in institutionalized older people. A total of 178 older people (≥ 60 years old) living in nursing homes in Natal/RN were included in the study. Cluster analysis was used to identify three groups according to their inflammatory state. Analysis anthropometric, biochemical, sociodemographic, and health-related variables was carried out. In sequence, an ordinal logistic regression was performed for a confidence level of 95% in those variables with p < 0.20 in the bivariate analysis. IL-6, TNF-α, zinc, low-density lipids (LDL), high-density lipids (HDL), and triglycerides were associated with inflamm-aging. The increase of 1 unit of measurement of LDL, HDL, and triglycerides increased the chance of inflammation-aging by 1.5%, 4.1%, and 0.9%, respectively, while the oldest old (≥ 80 years old) had an 84.9% chance of presenting inflamm-aging in relation to non-long-lived older people (< 80 years). The association between biochemical markers and inflamm-aging demonstrates a relationship between endothelial injury and the inflammatory state. In addition, the presence of a greater amount of fat in the blood may present a higher relative risk of death.

Exercisers' Affective and Enjoyment Responses: A Meta-Analytic and Meta-Regression Review.

Affective responses and enjoyment of exercise mediate exercise adherence, but previous research findings have failed to examine nuances that may moderate this relationship. We examined the effects of exercise on affective and enjoyment responses during and post exercise through a systematic literature review and meta-regression analysis. We searched major databases up to July 9, 2020 for studies evaluating healthy adults' acute and chronic responses to exercise, using either of The Feeling Scale or Physical Activity Enjoyment Scales. We calculated effect size (ES) values of 20 unique studies (397 participants; 40% females) as standardized differences in the means and expressed them as Hedges' g, together with the 95% confidence interval (95%CI). Among acute studies examining affective responses, we found a greater positive effect post exercise for continuous training (CT) compared to high intensity interval training (HIIT) (g = -0.61; 95%CI = -1.11, -0.10; p < .018), but there was no significant difference between these modes for effects during exercise. Subgroup analyses revealed that moderate, and not high intensity, CT, compared to HIIT, resulted in significantly greater positive affective responses (g = -1.09; 95%CI = -1.88, -0.30; p < .006). In contrast, enjoyment was greater for HIIT, compared to CT (g = 0.75; 95%CI = 0.17, -1.13; p = .010), but CT intensity did not influence this result. Among chronic studies, there was greater enjoyment following HIIT compared to CT, but these studies were too few to permit meta-analysis. We concluded that an acute bout of moderate intensity CT is more pleasurable, when measured post exercise than HIIT, but enjoyment is greater following HIIT, perhaps due to an interaction between effort, discomfort, time efficiency and constantly changing stimuli.

Reliability and validity of physical fitness tests in people with mental disorders: A systematic review and meta-analysis.

BACKGROUND: Several tests are available to assess the different components of physical fitness, including cardiorespiratory fitness, muscular strength, and flexibility. However, the reliability and validity of physical fitness tests in people with mental disorders has not been meta-analyzed. AIMS: To examine the reliability, concurrent, and convergent validity of physical fitness tests in people with mental disorders. METHODS: Studies evaluating the reliability, concurrent, and convergent validity of physical fitness tests in people with mental disorders were searched from major databases until January 20, 2020. Random-effects meta-analyses were performed pooling (1) reliability: test-retest correlations at two-time points, (2) convergent validity between submaximal tests and maximal protocols, or (3) concurrent validity between two submaximal tests. Associations are presented using r values and 95% confidence intervals. Methodological quality was assessed using the Quality Appraisal of Reliability Studies and the Critical Appraisal Tool. RESULTS: A total of 11 studies (N = 504; 34% females) were included. Reliability of the fitness tests, produced r values ranging from moderate (balance test-EUROFIT; [r = 0.75 (0.60-0.85); p = 0.0001]) to very strong (explosive leg power EUROFIT; [r = 0.96 (0.93-0.97); p = 0.0001]). Convergent validity between the 6-min walk test (6MWT) and submaximal cardiorespiratory tests was moderate (0.57 [0.26-0.77]; p = 0.0001). Concurrent validity between the 2-min walk test and 6MWT (r = 0.86 [0.39-0.97]; p = 0.0004) was strong. CONCLUSION: The present study demonstrates that physical fitness tests are reliable and valid in people with mental disorders.

Factors associated with sarcopenia in institutionalized elderly.

BACKGROUND: The diagnosis of sarcopenia is based on the analysis of strength, functionality and muscle mass. The objective was to verify the factors associated with sarcopenia in institutionalized elderly. METHODS: In total, 219 elderly individuals (≥60 years old) living in long-term institutions in Natal/RN were included in the study. After defining the elderly as sarcopenic or non-sarcopenic, anthropometric, biochemical, sociodemographic and health-related were analyzed. The Student t-test and Mann-Whitney test were used to analyze the quantitative, while the chi-square test was used for the qualitative variables. Finally, Poisson regression was used to provide prevalence ratios for those variables that presented differences in the bivariate analyses. RESULTS: Physical capacity and anthropometry were associated with sarcopenia. For each 1 cm of knee height, the elderly presented 2.71% more chance of not having sarcopenia, and eutrophic or overweight individuals (according to BMI) presented 37.71 and 91.81% chances, respectively, of not presenting sarcopenia. Elderly individuals who ambulate have a 30.08% chance of not being considered sarcopenic. In addition, biochemical and anthropometric indicators demonstrated a relationship of sarcopenia with malnutrition. CONCLUSION: Sarcopenia is associated with a loss of body mass, not only selective muscle mass, and greater physical inability to ambulate.

Pre-Exercise Screening Questionnaire: tradução do instrumento de triagem relacionado à COVID-19 / Pre-Exercise Screening Questionnaire: translation of the screening instrument related to COVID-19

A pandemia causada pela doença do coronavírus 2019 (COVID-19) e as medidas de distanciamento social provocaram reduções nos níveis de atividade física das pessoas. A atividade física está associada a uma melhor saúde física e mental, e manter a população ativa durante a pandemia é essencial. No entanto, ainda não se sabe se exercícios podem, em pessoas infectadas, causar uma potencial exacerbação de sintomas da COVID-19. O presente estudo objetivou traduzir o Pre-exercise screening questionnaire (PESQ) para o Português Brasileiro e de Portugal, para facilitar a sua utilização por profissionais ligados ao exercício físico não fluentes na língua inglesa. O PESQ contém sete perguntas diretas sobre os sintomas mais comuns de COVID-19 mais comumente encontrado em adultos e idosos, para orientação segura para prática de exercício físico. A tradução foi feita em 5 etapas: Tradução inicial, tradução cega, revisão da tradução, adequação da língua Portuguesa e ajustes e finalização. As etapas foram realizadas por pesquisadores experientes, com fluência em língua inglesa e nativos em português Brasileiro e de Portugal. No processo de tradução não houve divergências importantes entre os tradutores. A adaptação transcultural foi importante, pois, o português de Portugal difere-se do brasileiro. O instrumento foi devidamente traduzido e pode ser utilizado como ferramenta de screening para os sintomas da COVID-19 por profissionais do exercício durante a pandemia. No momento, o PESQ é a principal ferramenta disponível para prevenir danos relacionados à COVID-19 e a prática de exercícios

The 2019 pandemic caused by coronavirus disease (COVID-19) and measures of social detachment caused reductions in people's physical activity levels. Physical activity is associated with better physical and mental health, and keeping the population active during the pandemic is essential. However, it remains to be determined whether exercise can potentially exacerbate symptoms of COVID-19 in infected people. This study aimed to translate the Pre-exercise screening questionnaire (PESQ) into Brazilian Portuguese and Portugal, to facilitate its use by professionals linked to physical exercise who are not fluent in the English language. The PESQ has seven questions about the most common symptoms of COVID-19 seen in adults and older adults, providing safety to perform exercise. The translation was done in 5 steps: initial translation, blind translation, revision of the translation, adequacy of the Portuguese language and adjustments and finalization. The stages were carried out by experienced researchers, fluent in English and native speakers in Brazilian and Portuguese. There was no relevant disagreement within assessor in the translating procedure. The transcultural adaptation was crucial because Portuguese language varies across Brazil and Portugal. The instrument has been properly translated and can be used as a screening tool for the symptoms of COVID-19 by exercise professionals during the pandemic. Nowadays, the PESQ is the main available tool to prevent burden regarding COVID-19 and exercise practice

What is the impact of the European Consensus on the diagnosis and prevalence of sarcopenia among institutionalized elderly persons? / Qual o impacto do consenso europeu no diagnóstico e prevalência de sarcopenia em idosos institucionalizados?

Abstract Objective: To verify the impact of the European Consensus on the diagnosis and prevalence of sarcopenia among institutionalized elderly persons in Natal, Rio Grande do Norte, Brazil. Method: 219 elderly persons (≥60 years) of both genders were recruited for the study. Two criteria were initially used to calculate the prevalence of sarcopenia: criterion A, based on the European Consensus, considering only elderly persons with good physical and cognitive conditions and criterion B, considering all elderly individuals, regardless of their physical and/or cognitive condition. The association between sarcopenia and gender, age and body mass index (BMI) in the two groups was investigated using the chi-square test and the Student's t-test, with a significance level of 5%. Result: the diagnosis of sarcopenia according to Criterion A revealed a prevalence of 32% (95% CI: 22.54-43.21), whereas Criterion B identified a prevalence of 63.2% (95% CI: 56; 45-69,13). Despite the difference in the prevalence of sarcopenia using the two criteria employed (p<0.001), no differences were observed in terms of the association with gender (p=0.149, p=0.212), BMI (p<0.001, p<0.001), and age (p=0.904, p=353). Conclusion: including only elderly people with good physical and cognitive abilities to calculate sarcopenia, based on the European Consensus, underestimates the prevalence of this condition among institutionalized elderly. As elderly persons with physical or cognitive limitations are extremely typical in the population of care facilities and increased diagnostic calculation for sarcopenia did not interfere with the distribution of associated factors, it is recommended that these individuals are considered in the basis of calculation for future studies of the diagnosis and prevalence of sarcopenia. AU

Resumo Objetivo: verificar o impacto do consenso europeu no diagnóstico e prevalência de sarcopenia em idosos institucionalizados em Natal, RN, Brasil. Método: 219 idosos (≥60 anos) de ambos os sexos foram recrutados para o estudo. Inicialmente, foram comparados dois critérios para cálculo de prevalência da sarcopenia: critério A, segundo o consenso europeu, considerando apenas idosos com boas condições físicas e cognitivas e critério B, considerando todos idosos, independente da sua condição física e/ou cognitiva. Na sequência, foi investigada a associação da sarcopenia com sexo, idade e Índice de Massa Corporal (IMC) nos dois critérios diagnósticos, através do teste do qui-quadrado ou teste t deStudent, sendo considerado nível de significância de 5%. Resultados :O diagnóstico de sarcopenia segundo o Critério A apresentou uma prevalência de sarcopenia de 32% (IC95%: 22,54-43,21), enquanto o Critério B apresentou uma prevalência de 63,2% (IC95%: 56,45-69,13). Apesar da diferença encontrada na prevalência de sarcopenia entre os dois critérios utilizados (p<0,001), não foram observadas diferenças com relação à associação com sexo (p=0,149;p=0,212), IMC (p<0,001; p<0,001) e idade (p=0,904;p=0,353). Conclusão :Incluir apenas idosos com boa capacidade física e cognitiva para cálculo de sarcopenia, conforme estipulado pelo Consenso Europeu, subestima a prevalência de sarcopenia em idosos institucionalizados. Considerando que idosos com limitações físicas ou cognitivas são extremamente representativos para a população de idosos institucionalizados e que o acréscimo deles no cálculo diagnóstico para sarcopenia não interferiu na distribuição dos seus fatores associados, recomenda-se considerá-los na base de cálculo para estudos futuros de diagnóstico e prevalência de sarcopenia. AU

Can Transcranial Direct Current Stimulation Modulate Psychophysiological Response in Sedentary Men during Vigorous Aerobic Exercise?

This study evaluated whether transcranial direct current stimulation (tDCS) could change physiological and psychological responses during vigorous exercise with a constant load. 13 sedentary males (23.0±4.2 years; 25.6±4.2 kg/m²) took part in this randomized, crossed-over, sham-controlled, and double-blinded study. Participants underwent 2 sessions with anodal or sham tDCS (2 mA, 20 min) applied before exercise over the left temporal cortex targeting the left insular cortex. The exercise was performed at vigorous intensity (%HRmax 81.68±6.37) for 30 min. Heart rate (HR), rating of perceived exertion (RPE) and affective responses (pleasure/displeasure) were recorded at every 5 min. Additionally, heart rate variability (HRV) was measured before, immediately after and 60 min after the end of exercise. A 2-way repeated measure ANOVA showed that tDCS improved HRV neither at rest nor after exercise (p>0.15). Similarly, HR, RPE, and affective responses were not enhanced by tDCS during vigorous exercise (p>0.23). The findings of this study suggest that tCDS does not modulate either HRV at rest nor HR, RPE and affective responses during exercise. Transcranial direct current stimulation's efficiency might depend on the participants' levels of physical fitness and parameters of stimulation (e. g., duration, intensity, and arrangement of electrodes).

Prevalência de sarcopenia e envelhecimento inflamatório e fatores associados em idosos institucionalizados / Prevalence of sarcopenia and inflammatory aging and associated factors in institutionalized elderly people

Introdução: O diagnóstico da sarcopenia é restrito àqueles com boa capacidade física e cognitiva, não sendo adaptado às condições dos idosos institucionalizados. Além disso, apesar da perda de massa muscular ser determinante para seu diagnóstico, a redução associada à massa gorda tem sido observada na sarcopenia. Além disso, embora o estado inflamatório seja considerado um gatilho da perda de massa muscular, a redução no tecido adiposo tem sido associada à redução do estado inflamatório, concorrendo no construto teórico da associação entre envelhecimento inflamatório e sarcopenia. Objetivo: Discutir o diagnóstico para sarcopenia em idosos institucionalizados e verificar a associação entre envelhecimento inflamatório e sarcopenia, assim como analisar seus fatores associados. Metodologia: Três estudos foram conduzidos em idosos de ambos os sexos, residentes em instituições de longa permanência na cidade do Natal/RN. Nenhum estudo 1 (n=219) foi realizado uma adaptação do Consenso Europeu para Diagnóstico da Sarcopenia (2010) agregando idosos com baixa capacidade física e cognitiva. No estudo 2 (n=219) foi verificado quais os fatores estão associados à sarcopenia. No estudo 3 (n=187) foi realizada análise de conglomerados de idosos segundo seu estado inflamatório e selecionados os fatores associados a esta condição. Resultados: Inclusão de idosos com baixa condição física e cognitiva (estudo 1) acresceu em 32,2% a prevalência de sarcopenia. No estudo 2, os fatores associados à sarcopenia foram altura do joelho, eutrofia e excesso de peso (segundo IMC) e capacidade de deambular. No estudo 3 foi possível verificar que aumento de 1 unidade µg/dL no LDL, HDL e triglicerídeos constatou aumento de 1,5%, 4,1% e 0,9% a chance de envelhecimento inflamatório e idosos longevos (≥80 anos ) possuíram 84,9% mais de chance de envelhecimento inflamatório. Conclusão: Inclusão de idosos com baixa capacidade física e cognitiva para cálculo de sarcopenia é válida e representa de modo mais adequado os idosos institucionalizados, apresentando os aspectos antropométricos e físicos como seus principais fatores associados. Além disso, os indicadores bioquímicos e antropométricos demonstraram relação da sarcopenia com desnutrição. Além disso, não foi apresentada associação do inflamm-aging com sarcopenia, corroborando a construção de que na sarcopenia não ocorre perda seletiva da massa muscular (AU).

Introduction: The diagnosis of sarcopenia is restricted to those with good physical and cognitive capacity, not being adapted to the conditions of the institutionalized elderly. In addition, dispite the loss of muscle mass is determinant for its diagnosis, associated reduction of fat mass has been observed in sarcopenia. Although the inflammatory state is considered a trigger to loss of muscle mass, reduction in adipose tissue has been associated with the reduction of the inflammatory state, competing in the theoretical construct of the association between inflammation and sarcopenia. Objective: To discuss the diagnosis of sarcopenia in institutionalized elderly patients and to verify the association between inflammation and sarcopenia, as well as to analyze their associated factors. Methodology: Three studies were conducted in elderly people of both sexes, living in nursing homes in the city of Natal / RN. In study 1 (n = 219) an adaptation of the European Consensus for Diagnosis of Sarcopenia (2010) was carried out, adding elderly people with low physical and cognitive capacity. In study 2 (n = 219) it was verified which factors are associated with sarcopenia. In study 3 (n = 187), the analysis of elderly conglomerates according to their inflammatory state was performed and the factors associated with this condition were verified. Results: Inclusion of elderly people with low physical and cognitive status (study 1) increased the prevalence of sarcopenia by 32.2%. In study 2, the factors associated with sarcopenia were knee height, eutrophy and excess weight (according to BMI) and the ability to ambulate. In study 3 it was possible to verify that increase of 1 unit µg / dL in LDL, HDL and triglycerides presented a 1.5%, 4.1% and 0.9% increase in the chance of inflamm-aging and elderly individuals (≥80 years ) had an 84.9% greater chance of inflammation. Conclusion: Inclusion of elderly with low physical and cognitive capacity to calculate sarcopenia is valid and represents more appropriately the institutionalized elderly, presenting the anthropometric and physical aspects as their main associated factors. In addition, the biochemical and anthropometric indicators demonstrated a relationship of sarcopenia with malnutrition. In addition, no association of inflammation with sarcopenia was observed, corroborating the construct that in sarcopenia there is no selective muscle mass loss (AU).