RESUMEN
PURPOSE: Soft tissue sarcomas are rare malignant tumors. Liposarcoma constitutes the most frequent histological subtype of retroperitoneal sarcoma. The prognosis of soft tissue sarcomas depends on clinical and histologic characteristics. OBJECTIVE: Evaluate variables that may be related to the overall and local recurrence-free survival in patients with retroperitoneal liposarcoma and discuss the need for visceral resection en-bloc for tumors. METHODS: A retrospective analysis was conducted of the medical records of 60 patients seen between 1997 and 2017 who underwent surgical resection of retroperitoneal liposarcoma. RESULTS: The overall survival rate at 5 years of follow-up was 75.22% (95% confidence interval [CI] 0.58-0.86). The probability of a local recurrence-free survival at 5 years of follow-up was 26.04% (95% CI 0.11-0.44). The multivariate analysis showed that dedifferentiated or pleomorphic tumors and R2/fragmented resection were associated with a shorter time to recurrence. No other characteristics markedly influenced the overall survival (P > 0.05). CONCLUSION: Patients with dedifferentiated or pleomorphic tumors and incomplete resection were associated with higher local recurrence rates than others. This study reinforces the need for complete and en-bloc resection with organs when there is clear involvement or technical surgical difficulty to maintain the tumor integrity.
Asunto(s)
Liposarcoma , Neoplasias Retroperitoneales , Sarcoma , Humanos , Estudios Retrospectivos , Liposarcoma/cirugía , Liposarcoma/patología , Neoplasias Retroperitoneales/cirugía , Sarcoma/cirugía , Sarcoma/patología , Pronóstico , Tasa de Supervivencia , Recurrencia Local de NeoplasiaAsunto(s)
Adulto , Persona de Mediana Edad , Humanos , Masculino , Femenino , Colostomía , Irrigación Terapéutica , Colostomía/rehabilitaciónRESUMEN
Descreve-se a metodologia empregada para a elaboraçäo da previsäo de equipamentos específicos empregados na assistência à pacientes portadores de estomas intestinais e urinários, no Hospital das Clínicas da Faculdade de Medicina da Universidade de Säo Paulo. Também apresentam-se dados obtidos através desse estudo e tecem-se algumas consideraçöes finais