A system for treatment of diabetic foot ulcers using led irradiation and natural latex

Abstract Introduction: We developed and tested a new system for inducing the healing of diabetic foot ulcers. The system relies on the regenerative properties of its two components: an insole with a sheet of natural latex and a device that contains a matrix of light emitting diodes with wavelength of 635 nm. Methods The electronic and latex based devices were developed, and a four weeks test was performed in one control group (CG) of five ulcers and one experimental group (EG) of eight ulcers. The CG was treated with a standard approach, based on a silver-releasing foam dressing, and the EG was treated with the system under test. For each ulcer, an index for quantifying the percentage ulcer recovery, named CRU(%), has been calculated; a CRU(%) = 0% means no healing, and a CRU(%) = 100% means total healing. Results There were statistically significant increases of CRU(%) of 51.8% (p = 0.022), for the CG, and of 78.4% (p < 0.001), for the EG. The increase in the EG was higher than the increase in the CG, and the difference was statistically significant (p < 0.001). The results showed that the proposed method had, for these particular sets of ulcers, faster healing rates, than for the standard method. Conclusion The results hint that the proposed method seems promising as a future treatment method. However, the technique must undergo further testing before it can be considered for extensive clinical applications.

Electromyographic study in 5 muscles during an isometric fatiguing protocol.

In this study, 12 healthy men aging 22.8 ± 2.2 years old were submitted to a protocol of isometric resistance to fatigue contemplating elbow flexion on three different angles: 45°, 90° and 135°. The objective was to study electromyographic median frequency (MDF) in the following muscles: i) Biceps Brachialis Long Head (BBL), Brachioradialis (BRD), Flexor Digitorum Superficialis (FDS), Triceps Brachialis Long Head (TBL), and Extensor Digitorum (ED). It was verified that, for all muscles, including the muscles that act in opposition to the contraction, fatigue presence was verified by the decrease of MDF value.

Electromyographic evaluation of muscle recovery after isometric fatigue.

Despite growing interest in the behavior of electromyographic signals during muscle fatigue, few studies investigate fatigue recovery. In this work, we use surface electromyographic signals to determine the recovery time after isometric fatigue of the biceps brachii muscle in 90° flexion of the non-dominant elbow. Sixty volunteers were arranged into six experimental groups. Experiments were performed in three stages: reference phase (REF), fatigue resistance phase (RES), and recovery phase (REC). An isometric exercise was performed during the RES stage. The time interval between the RES and REC stages was different for each experimental group: 1, 2, 4, 8, 24 and 48 hours. Surface electromyographic signals were acquired during each phase, and the following electromyographic variables were calculated for each phase: median frequency (MDF), root mean squared (RMS) value, and maximum voluntary contraction (MVC). The REF data were compared with the REC data using a paired Wilcoxon test. The results show that the MVC is recovered 2 hours after the exercise. The MDF seems not to be fully recovered after 48 hours, but displays an apparent recovery trend.