RESUMEN
The medical use of psychedelic substances (e.g. psilocybin, ayahuasca, lysergic acid diethylamide and 3,4-methylenedioxymethamphetamine) is attracting renewed interest, driven by a pressing need for research and development of novel therapies for psychiatric disorders, as well as promising results of contemporary studies. In this Viewpoint, we reflect upon the 'Clinical Memorandum on Psychedelics' recently released by the Royal Australian and New Zealand College of Psychiatrists and note subsequent developments including the application for down-scheduling of psilocybin and 3,4-methylenedioxymethamphetamine presently being considered by the Therapeutic Goods Administration and approvals for access via the Special Access Scheme. We suggest that this field is worthy of rigorous research to assess potential benefits, address safety parameters and clarify therapeutic mechanisms. To this end, we outline recent research findings, provide an overview of current knowledge relating to mechanisms of action and discuss salient aspects of the psychedelic-assisted psychotherapy treatment model. The sum of this research points towards medicinal psychedelics as a potential new class of psychiatric treatments when used within a medically supervised framework with integrated psychotherapeutic support. However, before widespread translation into clinical use can occur, appropriately designed and sufficiently powered trials are required to detect both potential positive and negative outcomes. Unique safety and regulatory challenges also need to be addressed. As for any new medical therapy, psychedelic research needs to be conducted in a rigorous manner, through the dispassionate lens of scientific enquiry. Carte blanche availability to practitioners, without specific protocols and appropriate training, would be potentially harmful to individuals and detrimental to the field.
Asunto(s)
Alucinógenos , Australia , Alucinógenos/farmacología , Humanos , Dietilamida del Ácido Lisérgico , Salud Mental , Psilocibina/farmacologíaAsunto(s)
Reforma de la Atención de Salud/organización & administración , Hospitales Públicos/organización & administración , Australia , Financiación Gubernamental , Agencias Gubernamentales , Reforma de la Atención de Salud/economía , Reforma de la Atención de Salud/legislación & jurisprudencia , Historia del Siglo XXI , Humanos , Legislación HospitalariaRESUMEN
Our public hospitals need medical leadership, and partnerships with medical schools can provide it.
Asunto(s)
Reforma de la Atención de Salud , Hospitales Públicos/organización & administración , Hospitales de Enseñanza/organización & administración , Australia , Hospitales Públicos/normas , Hospitales de Enseñanza/normas , HumanosRESUMEN
Courtesy of the cashed-up Rockefeller Foundation (RF), opportunity knocked in the 1920s for university medical schools committed to closer integration with teaching hospitals. The University of Melbourne Medical School, recognising the opportunity to win RF funds to help with rebuilding, sought government support for an audacious plan consistent with the university-hospital-research triads designed to advance medical science, that had strong RF support. Using a range of local archival sources, this paper details the back story to the development of the plan in the mid-1920s and its presentation to the RF by a high-powered delegation from Victoria in 1927. Although a change of government undermined the attempt and the RF money went to Sydney, sufficient momentum survived to implement the plan in several forms over the following decades, contributing to Victoria's subsequent leadership role in medical science.
Asunto(s)
Investigación Biomédica/historia , Educación Médica/historia , Docentes Médicos/historia , Fundaciones/historia , Facultades de Medicina/historia , Historia del Siglo XIX , Historia del Siglo XX , Hospitales de Enseñanza/historia , Humanos , Enseñanza/historia , VictoriaRESUMEN
Partnership between research and health services has a long history in other countries, but has been relatively recent in Australia, with several models arising in the 1960s and 1970s as research-based specialties developed. Since the implementation of Medibank, which became Medicare, Australian Health Care Agreements have been primarily crafted on the basis of transactional numbers, ignoring the need for links with teaching and research and the need to implement new developments. Education and research have been seen as the responsibility of the federal government, and hospitals are progressively less recognised or funded for these functions by the states. Australia's teaching hospitals are in danger of falling seriously behind those in other countries and losing their capacity to monitor quality, to innovate and to branch into new strategies in partnership with primary care services. We should look at initiatives in other countries such as the United Kingdom and Canada, which are making big strides in tackling similar issues. University hospitals hold the key, if appropriately linked with other services. The current Australian Health Care Agreements are on hold. A new agency is needed to support clinical and service-related research, with a new structure and track for federal government funding, and providing oversight of research and development, of clinical governance and quality of outcomes in health care, linked with new strategies for prevention and treatment. A component of the foreshadowed additional federal government funding for health should be sequestered to set up such an agency.
Asunto(s)
Educación Médica/organización & administración , Investigación sobre Servicios de Salud/organización & administración , Hospitales Universitarios/organización & administración , Australia , HumanosRESUMEN
Our democratic processes have moved on - so must our science.