Facial first impressions are not mandatory: A priming investigation.

A common assertion is that, based around prominent character traits, first impressions are spontaneously extracted from faces. Specifically, mere exposure to a person is sufficient to trigger the involuntary extraction of core personality characteristics (e.g., trustworthiness, dominance, competence), an outcome that supports a range of significant judgments (e.g., hiring, investing, electing). But is this in fact the case? Noting ambiguities in the extant literature, here we used a repetition priming procedure to probe the extent to which impressions of dominance are extracted from faces absent the instruction to evaluate the stimuli in this way. Across five experiments in which either the character trait of interest was made increasingly obvious to participants (Expts. 1-3) or attention was explicitly directed toward the faces to generate low-level/high-level judgments (Expts. 4 & 5), no evidence for the spontaneous extraction of first impressions was observed. Instead, priming only emerged when judgments of dominance were an explicit requirement of the task at hand. Thus, at least using a priming methodology, the current findings contest the notion that first impressions are a mandatory product of person perception.

The power of the unexpected: Prediction errors enhance stereotype-based learning.

Stereotyping is a ubiquitous feature of social cognition, yet surprisingly little is known about how group-related beliefs influence the acquisition of person knowledge. Accordingly, in combination with computational modeling (i.e., Reinforcement Learning Drift Diffusion Model analysis), here we used a probabilistic selection task to explore the extent to which gender stereotypes impact instrumental learning. Several theoretically interesting effects were observed. First, reflecting the impact of cultural socialization on person construal, an expectancy-based preference for stereotype-consistent (vs. stereotype-inconsistent) responses was observed. Second, underscoring the potency of unexpected information, learning rates were faster for counter-stereotypic compared to stereotypic individuals, both for negative and positive prediction errors. Collectively, these findings are consistent with predictive accounts of social perception and have implications for the conditions under which stereotyping can potentially be reduced.

People perception and stereotype-based responding: task context matters.

Whether group impact social perception is a topic of renewed theoretical and empirical interest. In particular, it remains unclear when and how the composition of a group influences a core component of social cognition-stereotype-based responding. Accordingly, exploring this issue, here we investigated the extent to which different task requirements moderate the stereotype-related products of people perception. Following the presentation of same-sex groups that varied in facial typicality (i.e., high or low femininity/masculinity), participants had to report either the gender-related status of target words (i.e., a group-irrelevant gender-classification task) or whether the items were stereotypic or counter-stereotypic with respect to the preceding groups (i.e., a group-relevant stereotype-status task). Critically, facial typicality only impacted performance in the stereotype-status task. A further computational analysis (i.e., Diffusion Model) traced this effect to the combined operation of stimulus processing and response biases during decision-making. Specifically, evidence accumulation was faster when targets followed groups that were high (vs. low) in typicality and these arrays also triggered a stronger bias toward stereotypic (vs. counter-stereotypic) responses. Collectively, these findings elucidate when and how group variability influences people perception.

Outside the Safe Operating Space of the Planetary Boundary for Novel Entities.

We submit that the safe operating space of the planetary boundary of novel entities is exceeded since annual production and releases are increasing at a pace that outstrips the global capacity for assessment and monitoring. The novel entities boundary in the planetary boundaries framework refers to entities that are novel in a geological sense and that could have large-scale impacts that threaten the integrity of Earth system processes. We review the scientific literature relevant to quantifying the boundary for novel entities and highlight plastic pollution as a particular aspect of high concern. An impact pathway from production of novel entities to impacts on Earth system processes is presented. We define and apply three criteria for assessment of the suitability of control variables for the boundary: feasibility, relevance, and comprehensiveness. We propose several complementary control variables to capture the complexity of this boundary, while acknowledging major data limitations. We conclude that humanity is currently operating outside the planetary boundary based on the weight-of-evidence for several of these control variables. The increasing rate of production and releases of larger volumes and higher numbers of novel entities with diverse risk potentials exceed societies' ability to conduct safety related assessments and monitoring. We recommend taking urgent action to reduce the harm associated with exceeding the boundary by reducing the production and releases of novel entities, noting that even so, the persistence of many novel entities and/or their associated effects will continue to pose a threat.

More or less of me and you: self-relevance augments the effects of item probability on stimulus prioritization.

Self-relevance exerts a powerful influence on information processing. Compared to material associated with other people, personally meaningful stimuli are prioritized during decision-making. Further exploring the character of this effect, here we considered the extent to which stimulus enhancement is impacted by the frequency of self-relevant versus friend-relevant material. In a matching task, participants reported whether shape-label stimulus pairs corresponded to previously learned associations (e.g., triangle = self, square = friend). Crucially however, before the task commenced, stimulus-based expectancies were provided indicating the probability with which both self- and friend-related shapes would be encountered. The results revealed that task performance was impacted by the frequency of stimulus presentation in combination with the personal relevance of the items. When self- and friend-related shapes appeared with equal frequencies, a self-prioritization effect emerged (Expt. 1). Additionally, in both confirmatory (Expt. 2) and dis-confirmatory (Expt. 3) task contexts, stimuli that were encountered frequently (vs. infrequently) were prioritized, an effect that was most pronounced for self-relevant (vs. friend-relevant) items. Further computational analyses indicated that, in each of the reported experiments, differences in performance were underpinned by variation in the rate of information uptake, with evidence extracted more rapidly from self-relevant compared to friend-relevant stimuli. These findings advance our understanding of the emergence and origin of stimulus-prioritization effects during decisional processing.

Comparing person and people perception: Multiple group members do not increase stereotype priming.

A characteristic feature of daily life is encountering people in groups. Surprisingly, however, at least during the initial stages of processing, research has focused almost exclusively on the construal of single individuals. As such, it remains unclear whether person and people (i.e., group) perception yield comparable or divergent outcomes. Addressing this issue, here we explored a core social-cognitive topic-stereotype activation-by presenting both single and multiple facial primes in a sequential-priming task. In addition, the processes underlying task performance were probed using a drift diffusion model analysis. Based on prior work, it was hypothesised that multiple (vs. single) primes would increase stereotype-based responding. Across two experiments, a consistent pattern of results emerged. First, stereotype priming was insensitive to the number of primes that were presented and occurred only at a short prime-target stimulus onset asynchrony (i.e., 250 ms). Second, priming was underpinned by a bias towards congruent (vs. incongruent) prime-target responses. Collectively these findings advance understanding of the emergence and origin of stereotype priming during person and people perception.

On stopping yourself: Self-relevance facilitates response inhibition.

It is well documented that stimuli associated with the self are easier to process than identical material paired with other people (i.e., self-prioritization effect). Surprisingly, however, relatively little is known about how self-relevance impacts core aspects of executive functioning, notably response inhibition. Accordingly, here we used a stop-signal task to establish how effectively responses toward self-relevant (vs. other-relevant) stimuli can intentionally be inhibited. In the context of personal possession, participants were required to classify stimuli (i.e., pens and pencils) based on ownership (i.e., owned-by-self vs. owned-by-friend/stranger), unless an occasional auditory tone indicated that the response should be withheld. The results revealed the benefits of self-relevance on response inhibition. Compared with items owned by a friend or stranger, responses to self-owned objects were inhibited more efficiently. These findings confirm that self-relevance facilitates executive control.

Self-prioritization during stimulus processing is not obligatory.

An emerging literature has suggested that self-relevance automatically enhances stimulus processing (i.e., the self-prioritization effect). Specifically, during shape-label matching tasks, geometric shapes associated with the self are identified more rapidly than comparable stimuli paired with other targets (e.g., friend, stranger). Replicating and extending work that challenges the putative automaticity of this effect, here we hypothesized that self-relevance facilitates stimulus processing only when task sets draw attention to previously formed shape-label associations in memory. The results of a shape-classification task confirmed this prediction. Compared to shapes associated with a friend, those paired with the self were classified more rapidly when participants were required to report who the stimulus denoted (i.e., self or friend). In contrast, self-relevance failed to facilitate performance when participants judged either what the shape was (i.e., triangle or square, diamond or circle) or where it was located on the screen (i.e., above or below fixation). These findings further elucidate the conditions under which self-relevance does-and does not-influence stimulus processing.

Self-relevance enhances evidence gathering during decision-making.

Despite repeated demonstrations that self-relevant material is prioritized during stimulus appraisal, a number of unresolved issues remain. In particular, it is unclear if self-relevance facilitates task performance when stimuli are encountered under challenging processing conditions. To explore this issue, using a backward masking procedure, here participants were required to report if briefly presented objects (pencils and pens) had previously been assigned to the self or a best friend (i.e., object-ownership task). The results yielded a standard self-ownership effect, such that responses were faster and more accurate to self-owned (vs. friend-owned) objects. In addition, a drift diffusion model analysis indicated that this effect was underpinned by a stimulus bias. Specifically, evidence was accumulated more rapidly from self-owned compared to friend-owned stimuli. These findings further elucidate the extent and origin of self-prioritization during decisional processing.

It's not always about me: The effects of prior beliefs and stimulus prevalence on self-other prioritisation.

Although self-relevance is widely acknowledged to enhance stimulus processing, the exclusivity of this effect remains open to question. In particular, in commonly adopted experimental paradigms, the prioritisation of self-relevant (vs. other-relevant) material may reflect the operation of a task-specific strategy rather than an obligatory facet of social-cognitive functioning. By changing basic aspects of the decisional context, it may therefore be possible to generate stimulus-prioritisation effects for targets other than the self. Based on the demonstration that ownership facilitates object categorisation (i.e., self-ownership effect), here we showed that stimulus prioritisation is sensitive to prior expectations about the prevalence of forthcoming objects (owned-by-self vs. owned-by-friend) and whether these beliefs are supported during the task. Under conditions of stimulus uncertainty (i.e., no prior beliefs), replicating previous research, objects were classified more rapidly when owned-by-self compared with owned-by-friend (Experiment 1). When, however, the frequency of stimulus presentation either confirmed (Experiment 2) or disconfirmed (Experiment 3) prior expectations, stimulus prioritisation was observed for the most prevalent objects regardless of their owner. A hierarchical drift diffusion model (HDDM) analysis further revealed that decisional bias was underpinned by differences in the evidential requirements of response generation. These findings underscore the flexibility of ownership effects (i.e., stimulus prioritisation) during object processing.

Stereotype-based priming without stereotype activation: A tale of two priming tasks.

An extensive literature has demonstrated stereotype-based priming effects. What this work has only recently considered, however, is the extent to which priming is moderated by the adoption of different sequential-priming tasks and the attendant implications for theoretical treatments of person perception. In addition, the processes through which priming arises (i.e., stimulus and/or response biases) remain largely unspecified. Accordingly, here we explored the emergence and origin of stereotype-based priming using both semantic- and response-priming tasks. Corroborating previous research, a stereotype-based priming effect only emerged when a response-priming (vs. semantic-priming) task was used. A further hierarchical drift diffusion model analysis revealed that this effect was underpinned by differences in the evidential requirements of response generation (i.e., a response bias), such that less evidence was needed when generating stereotype-consistent compared with stereotype-inconsistent responses. Crucially, information uptake (i.e., stimulus bias, efficiency of target processing) was faster for stereotype-inconsistent than stereotype-consistent targets. This reveals that stereotype-based priming originated in a response bias rather than the automatic activation of stereotypes. The theoretical implications of these findings are considered.

Stop stereotyping.

Restraining the expression of stereotypes is a necessary requirement for harmonious living, yet surprisingly little is known about the efficacy of this process. Accordingly, in two experiments, here we used a stop-signal task to establish how effectively stereotype-related responses can be inhibited. In Experiment 1, following the presentation of gender-typed occupational contexts, participants reported the sex of target faces (i.e., Go trials) unless an occasional auditory tone indicated they should withhold their response (i.e., Stop trials). In Experiment 2, following the presentation of male and female faces, participants made either stereotypic or counter-stereotypic judgments, unless a stop signal was presented. Regardless of whether stereotyping was probed indirectly (Experiment 1) or directly (Experiment 2), a consistent pattern of results was observed; inhibition was faster for stereotypic compared with counter-stereotypic responses. These findings demonstrate that stopping stereotyping may be less challenging than has widely been assumed.

Predictably confirmatory: The influence of stereotypes during decisional processing.

Stereotypes facilitate the processing of expectancy-consistent (vs expectancy-inconsistent) information, yet the underlying origin of this congruency effect remains unknown. As such, here we sought to identify the cognitive operations through which stereotypes influence decisional processing. In six experiments, participants responded to stimuli that were consistent or inconsistent with respect to prevailing gender stereotypes. To identify the processes underpinning task performance, responses were submitted to a hierarchical drift diffusion model (HDDM) analysis. A consistent pattern of results emerged. Whether manipulated at the level of occupational (Expts. 1, 3, and 5) or trait-based (Expts. 2, 4, and 6) expectancies, stereotypes facilitated task performance and influenced decisional processing via a combination of response and stimulus biases. Specifically, (1) stereotype-consistent stimuli were classified more rapidly than stereotype-inconsistent stimuli; (2) stereotypic responses were favoured over counter-stereotypic responses (i.e., starting-point shift towards stereotypic responses); (3) less evidence was required when responding to stereotypic than counter-stereotypic stimuli (i.e., narrower threshold separation for stereotypic stimuli); and (4) decisional evidence was accumulated more efficiently for stereotype-inconsistent than stereotype-consistent stimuli and when targets had a typical than atypical facial appearance. Collectively, these findings elucidate how stereotypes influence person construal.

Exploring the planetary boundary for chemical pollution.

Rockström et al. (2009a, 2009b) have warned that humanity must reduce anthropogenic impacts defined by nine planetary boundaries if "unacceptable global change" is to be avoided. Chemical pollution was identified as one of those boundaries for which continued impacts could erode the resilience of ecosystems and humanity. The central concept of the planetary boundary (or boundaries) for chemical pollution (PBCP or PBCPs) is that the Earth has a finite assimilative capacity for chemical pollution, which includes persistent, as well as readily degradable chemicals released at local to regional scales, which in aggregate threaten ecosystem and human viability. The PBCP allows humanity to explicitly address the increasingly global aspects of chemical pollution throughout a chemical's life cycle and the need for a global response of internationally coordinated control measures. We submit that sufficient evidence shows stresses on ecosystem and human health at local to global scales, suggesting that conditions are transgressing the safe operating space delimited by a PBCP. As such, current local to global pollution control measures are insufficient. However, while the PBCP is an important conceptual step forward, at this point single or multiple PBCPs are challenging to operationalize due to the extremely large number of commercial chemicals or mixtures of chemicals that cause myriad adverse effects to innumerable species and ecosystems, and the complex linkages between emissions, environmental concentrations, exposures and adverse effects. As well, the normative nature of a PBCP presents challenges of negotiating pollution limits amongst societal groups with differing viewpoints. Thus, a combination of approaches is recommended as follows: develop indicators of chemical pollution, for both control and response variables, that will aid in quantifying a PBCP(s) and gauging progress towards reducing chemical pollution; develop new technologies and technical and social approaches to mitigate global chemical pollution that emphasize a preventative approach; coordinate pollution control and sustainability efforts; and facilitate implementation of multiple (and potentially decentralized) control efforts involving scientists, civil society, government, non-governmental organizations and international bodies.

Sustainability. Planetary boundaries: guiding human development on a changing planet.

The planetary boundaries framework defines a safe operating space for humanity based on the intrinsic biophysical processes that regulate the stability of the Earth system. Here, we revise and update the planetary boundary framework, with a focus on the underpinning biophysical science, based on targeted input from expert research communities and on more general scientific advances over the past 5 years. Several of the boundaries now have a two-tier approach, reflecting the importance of cross-scale interactions and the regional-level heterogeneity of the processes that underpin the boundaries. Two core boundaries­climate change and biosphere integrity­have been identified, each of which has the potential on its own to drive the Earth system into a new state should they be substantially and persistently transgressed.

Identifying chemicals that are planetary boundary threats.

Rockström et al. proposed a set of planetary boundaries that delimit a "safe operating space for humanity". Many of the planetary boundaries that have so far been identified are determined by chemical agents. Other chemical pollution-related planetary boundaries likely exist, but are currently unknown. A chemical poses an unknown planetary boundary threat if it simultaneously fulfills three conditions: (1) it has an unknown disruptive effect on a vital Earth system process; (2) the disruptive effect is not discovered until it is a problem at the global scale, and (3) the effect is not readily reversible. In this paper, we outline scenarios in which chemicals could fulfill each of the three conditions, then use the scenarios as the basis to define chemical profiles that fit each scenario. The chemical profiles are defined in terms of the nature of the effect of the chemical and the nature of exposure of the environment to the chemical. Prioritization of chemicals in commerce against some of the profiles appears feasible, but there are considerable uncertainties and scientific challenges that must be addressed. Most challenging is prioritizing chemicals for their potential to have a currently unknown effect on a vital Earth system process. We conclude that the most effective strategy currently available to identify chemicals that are planetary boundary threats is prioritization against profiles defined in terms of environmental exposure combined with monitoring and study of the biogeochemical processes that underlie vital Earth system processes to identify currently unknown disruptive effects.

Elevated antibody reactivity to measles virus NCORE protein among patients with multiple sclerosis and their healthy siblings with intrathecal oligoclonal immunoglobulin G production.

BACKGROUND: Patients with multiple sclerosis (MS) and their healthy siblings with the MS oligoclonal bands (OCB) trait, (a hyperimmune condition in form of two or more CSF enriched OCBs) harbor in cerebrospinal fluid (CSF) and serum elevated immunoglobulin G (IgG) titers against measles crude whole-cell antigen. The underlying mechanism resulting in the increased IgG antibody reactivity to measles remains unclear. The response may represent specific IgG reactivity to measles antigens or unspecific auto-antibodies targeting cellular components in the crude whole virus antigens commonly used in detection assays. OBJECTIVE: To determine the specificity of the measles IgG antibody reactivity by using a purified single nucleoprotein as antigen, thereby minimizing the contribution from auto-antibodies. STUDY DESIGN: The conserved N-terminal portion of the measles nucleocapsid protein (NCORE) was expressed as a specific antigen devoid of human or primate components. Serological analyses were performed on CSF and sera from MS patients, their clinically healthy siblings and healthy unrelated controls. RESULTS: MS patients demonstrated higher IgG reactivity compared to healthy controls in both CSF (P<0.001) and serum (P<0.001), and compared to siblings in CSF (P<0.001) and serum (P=0.2). Siblings with MS OCB trait showed higher IgG reactivity than healthy controls in CSF (P=0.002) and serum (P=0.01). Comparison between siblings with MS OCB trait and siblings without MS OCB trait showed (P=0.04) for CSF and (P=0.08) for serum. CONCLUSION: These findings suggest a measles-specific component in the antibody reactivity demonstrated by MS patients and their siblings with the MS OCB trait.

Confronting unknown planetary boundary threats from chemical pollution.

Rockström et al. proposed a set of planetary boundaries that delimitate a "safe operating space for humanity". One of the planetary boundaries is determined by "chemical pollution", however no clear definition was provided. Here, we propose that there is no single chemical pollution planetary boundary, but rather that many planetary boundary issues governed by chemical pollution exist. We identify three conditions that must be simultaneously met for chemical pollution to pose a planetary boundary threat. We then discuss approaches to identify chemicals that could fulfill those conditions, and outline a proactive hazard identification strategy that considers long-range transport and the reversibility of chemical pollution.

Recombinant glycoprotein E produced in mammalian cells in large-scale as an antigen for varicella-zoster-virus serology.

A recombinant glycoprotein E (gE) from varicella-zoster virus (VZV) was generated and produced in Chinese Hamster Ovary (CHO) cells, in the development of a specific antigen for analysis of IgG antibodies to VZV. Several stable gE-secreting clones were established and one clone was adapted to growth in serum-free suspension culture. When the cells were cultured in a perfusion bioreactor, gE was secreted into the medium, from where it could be easily purified. The recombinant gE was then evaluated as a serological antigen in ELISA. When compared to a conventional whole virus antigen, the VZV gE showed similar results in ELISA-based seroprevalence studies of 854 samples derived from blood donors, students, ischemic stroke patients and their controls, including samples with border-line results in previous analyses. Eight samples (0.9%) were discordant, all being IgG-negative by the VZV gE ELISA and positive by the whole virus ELISA. The sensitivity and specificity of the VZV gE ELISA were 99.9% and 100%, respectively, compared to 100% and 88.9% for the VZV whole virus ELISA. The elderly subjects showed similar reactivities to both antigens, while VZV gE gave lower signals in the younger cohorts, suggesting that antibodies to gE may increase with age. It was concluded that the recombinant VZV gE from CHO cells was suitable as a serological antigen for the detection of IgG antibodies specific for VZV.