Quantity and quality are increasing but there's room for improvement: A scoping review of physical activity intervention trials.

BACKGROUND: Observing trends in research publications helps to identify the quantity and quality of research produced, as well as reveal evidence gaps. No comprehensive review of the quality and quantity of physical activity intervention trials has been conducted. OBJECTIVE: We aimed to investigate i) the volume and quality (and changes in these over time) of randomized controlled trials evaluating physical activity interventions, and ii) the association between journal ranking and trial quality. METHODS: We searched the Physiotherapy Evidence Database (PEDro) for trials investigating physical activity interventions (no restrictions for population, comparison, or language). Descriptive statistics were used to describe the volume and quality of trials. The association between journal ranking (Journal Impact Factor) and trial quality (PEDro Scale) was examined using Spearman's rho correlation. RESULTS: We identified 1779 trials, of which 40% (n = 710) were published between 2016 and 2020. The mean (SD) total PEDro score was 5.3 (1.5) points out of 10, increasing over time from 2.5 (0.7) points in 1975-1980 to 5.6 (1.4) points in 2016-2020. Quality criteria that were least reported included blinding of intervention deliverers (therapists) (n = 3, 0.2%), participants (n = 21, 1.2%), or assessors (n = 541, 31%); concealed allocation to groups (n = 526, 30%); and intention to treat analysis (n = 764, 43%). There was a small correlation between trial quality and Journal Impact Factor (0.21, p < 0.001). CONCLUSION: A large volume of trials has investigated physical activity interventions. The quality of these trial reports is suboptimal but improving over time. Journal ranking should not be used for selecting high quality trials.

Diet quality index and its components have not associated with the development of breast cancer risk assessed by the diet quality index: a case-control study.

OBJECTIVE: To investigate if the diet quality and its components are associated with breast cancer risk. METHODS: A case-control study was conducted with 332 women, 114 who were diagnosed with breast cancer, and 218 control individuals. Groups were matched for age, body mass index, and menopausal status. The quality of diet was assessed using Brazilian Healthy Eating Index Revised (BHEI-R) and its components. Food consumption was measured through three 24-h dietary recalls and assessed using the NDS-R software. For statistical analyses, it was performed an adjusted logistic regression, estimation of the Odds Ratio (OR), and 95% confidence interval (95%CI), with a p-value <0.05. RESULTS: The BHEI-R score, classified into quartiles, did not differ between groups in the lowest quartile of diet quality (p=0.853). The components total cereals (p=0.038), saturated fat (p=0.039) and Gord_AA (fat, alcohol, and added sugar) (p=0.023) had higher scores among the case group. The scores for total fruits (p=0.010) and milk and dairy products (p=0.039) were higher among the control group. The BHEI-R components and the quality of diet were not associated with the outcome. CONCLUSION: Diet quality, assessed by the BHEI-R and its components, was not associated with breast cancer.

Otimização das etapas de confecção do protocolo Branemark com carga tardia utilizando o guia multifuncional / Optimization of the Branemark protocol late load preparation steps using the multifunctional guide

O "planejamento reverso" em implantodontia busca alcançar um melhor prognóstico para a reabilitação do paciente, permitindo uma maior previsibilidade para o tratamento a partir do momento em que se planeja a reabilitação oral protética antes mesmo de planejar os implantes osseointegráveis. O dispositivo de resina acrílica chamado guia multifuncional representa a disposição final dos dentes na reabilitação e auxilia demasiadamente na etapa protética em casos em que não é possível a carga imediata. Ainda, otimiza o número de consultas do tratamento pois orienta a relação maxilomandibular, dimensão vertical e correta posição dos dentes. O presente trabalho tem como objetivo apresentar um caso clínico da utilização do guia multifuncional para moldagem dos implantes em caso de protocolo Branemark com dois tempos cirúrgicos, mostrando sua utilidade para diminuição do número de consultas na etapa de confecção da prótese total inferior definitiva. Diante dos resultados obtidos na realização do caso, foi possível concluir que nos casos de protocolo Branemark quando não é possível realizar a carga imediata, o guia multifuncional pode ser aproveitado e utilizado com sucesso, para a moldagem e confecção da prótese definitiva, diminuindo o número de consultas e otimizando o tratamento.

Reverse planning in implantology aims to improve patient's rehabilitation prognosis allowing greater treatment predictability from the prosthetic planning and before the implants installation. The acrylic resin device called multifunctional guide represents the final teeth disposition and is very useful in the prosthetic step when immediate loading is not possible. And it optimizes appointments treatment number since it guides the maxillomandibular relation, vertical dimension and correct teeth position. The aim of this study was to present a clinical case using the multifunctional guide for implant molding a two steps Branemark protocol, showing its usefulness to reduce the appointments number during the inferior total denture preparation step. Based on these results, it was possible to conclude that in Branemark protocol, when it immediate loading is not possible, the multifunctional guide can be used successfully for molding and making the final prosthesis, reducing the number of visits and optimizing treatment.

Implante transitório de corpo único com ativação imediata para retenção de prótese total provisória - relato de caso / Single body transient implants immediate activated for provisional prosthesis retention ­ case report

A reabilitação protética ganhou um componente que veio solucionar problemas de pessoas edentadas que até então pareciam sem solução. Trata-se dos implantes osseointegráveis, introduzidos pelo professor Per Ingvar Branemark entre os anos 70 e 80, e que, nos dias de hoje, se tornou na maioria dos casos, a primeira opção para a reabilitação oral. No caso de edentados totais na mandíbula, a prótese total fixa sobre implantes instalados entre os forames mentuais é um tipo de tratamento reabilitador com elevado grau de sucesso. Nos casos onde não é possível a colocação da prótese fixa com carga imediata após a instalação dos implantes, o paciente pode usar uma prótese total provisória, diretamente sobre os implantes permanentes instalados ou retida por implantes transitórios de corpo único, com encaixe tipo bola/o'ring. O presente artigo relata um caso clinico com utilização de implantes transitórios de corpo único para reter prótese total provisória, durante o tempo da osseointegração dos implantes permanentes.

Prosthetic rehabilitation gained a component that solved problems of edentulous people. These are the Osseo integrative implants, introduced by Professor Per Ingvar Branemark between the 1970s and 1980s, and which has become in most cases the first option for oral rehabilitation. In the case of mandible total edentulous, the total fixed prosthesis on implants installed between the mental foramina is a type of rehabilitation treatment with a high degree of success. In cases where it is not possible to place the fixed prosthesis with immediate loading after implant installation, the patient may use a provisional total prosthesis, directly on the permanent implants installed or retained by transient implants of single body, ball-type fitting 'ring. The present article reports a clinical case with the use of single body transient implants to retain temporary total prosthesis during the time of osseointegration of permanent implants.

Does sedentary behaviour contribute to the development of a new episode of low back pain? A systematic review of prospective cohort studies.

OBJECTIVE: To investigate whether the sedentary behaviour contributes to the development of new episodes of low back pain in adults. METHODS: Searches were performed in five electronic databases from their inception to March 2022. Prospective cohort studies with people without low back pain at baseline investigating the effect of sedentary behaviour on the development of new episodes of low back pain at follow-up were considered eligible. Two independent authors screened, extracted the data and assessed the risk of bias of included studies. An adapted version of the Quality In Prognosis Studies (QUIPS) tool was used to assess the risk of bias. Meta-analyses were performed using random effect models to obtain a pooled risk ratio (RR) and 95% confidence intervals (CIs). Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to assess the overall certainty of the evidence. RESULTS: Ten studies were included in this review, with a total sample ranging from 107 to 57,504 participants and mean age ranging from 21.7 to 53.6 years. Most studies (n = 9) assessed sedentary behaviour using self-reported methods, including validated questionnaires or single questions, except for one study that used video recording. The overall risk of bias of the included studies was low. Pooled analysis showed that people classified as sedentary or spending more time in sedentary activities were not likely to develop a new episode of low back pain (RR 1.01, 95% CI 0.98-1.04, I2  = 9%, n = 9 studies, moderate evidence). CONCLUSION: Sedentary behaviour probably does not contribute to the development of new episodes of low back pain in an adult population. SIGNIFICANCE: Sedentary behaviour does not appear to increase the chances of developing a new episode of low back pain. This might imply that health lifestyle contributors seem to be more related to the amount and type of physical activity, but not the amount of sedentary time. However, studies evaluating the relationship of the sedentary and physical activity with the development of a new episode of low back pain are still needed.

Treatment of Triple Negative Cell Lines with Olaparib to Block DNA Repair.

BACKGROUND: The most aggressive breast cancer is the triple negative histological type, and the gold standard for its treatment is platinum salts, such as carboplatin. Due to high recurrence, there is a need to test new drugs, such as PARP inhibitors (PARPi), that induce lethality in cells with DNA damage. Olaparib is a PARPi, already used in some tumors but not tested in canine species. Thus, the aim of this study was to demonstrate the efficacy of olaparib in inhibiting DNA repair and control disease progression by decreasing the migration capacity of mammary tumor cells. METHODS: The cell lines CF41.Mg and MDA-MB-468 were cultured and MTT was performed to define the best dose of carboplatin. Next, the cells were treated with 10 µM carboplatin, olaparib, and with a combination of both for 24 hours. PARP-1 protein and gene expression were evaluated by immunofluorescence, western blotting, and qRT-PCR, respectively. The analysis of cell migration was performed in transwell chambers. RESULTS: For CF41.Mg and MDA-MB-468 cell lines, there was a decrease in PARP-1 protein and gene expression after treatment with carboplatin, olaparib, and both in combination compared to the group without treatment (control) (p<0.05). Moreover, in both lines, a reduction in invasion rate was observed after treatment with carboplatin, olaparib and when combined, compared to the control group (p<0.05). CONCLUSION: Our data suggest that carboplatin and olaparib were able to block DNA repair and control the cancer invasion, especially when used in combination. The results with olaparib in the canine line are unpublished. The olaparib should be a possible agent against human breast cancer and canine mammary tumors.

Liquid biopsy can detect BRCA2 gene variants in female dogs with mammary neoplasia.

Mammary tumours (MT) are one of the most prevalent malignancies in female dogs and women. Currently, molecular analyzes have shown that each tumour type presents its own genetic signature. In this context, liquid biopsy allows a comprehensive genetic characterisation of the tumour, enabling early diagnosis and personalised treatment of patients. In women, deleterious mutations inherited in BRCA2 gene are associated with an increased risk of breast cancer, resistance to therapies and worse prognosis. In female dogs, there are many divergent data on the involvement of BRCA2 gene with mammary carcinogenesis and what its pathogenic potential is. Therefore, the objective was to identify BRCA2 gene variants in 20 plasma DNA samples, from 10 newly diagnosed dogs with mammary cancer (RD), five control (CTR) and five mastectomized patients. Eleven single nucleotide polymorphisms (SNPs) were detected, most of them in the exon 11 and two indels (deletion/insertion) in the BRCA2 gene. However, there was no statistically significant difference in the SNPs/indels detected between the groups. In addition, only one SNP (p.T1425P) and one deletion (p.L2307del) were considered deleterious using in silico computational models. Interestingly, most common variants were present in the plasma of all groups, except for the Ile2614Thr, Ile2614Val, Thr1425Pro and p.L2307del variants. Thus, we observed that SNPs are common in the BRCA2 gene of female dogs with MT, with a similar condition identified in women with breast cancer. Liquid biopsy approach in dogs with MT is useful for genetic and therapeutic proposals.

Diet quality index and its components have not associated with the development of breast cancer risk assessed by the diet quality index: a case-control study / Índice de qualidade da dieta e seus componentes não se associaram ao desenvolvimento de câncer de mama: um estudo caso-controle

ABSTRACT Objective: To investigate if the diet quality and its components are associated with breast cancer risk. Methods: A case-control study was conducted with 332 women, 114 who were diagnosed with breast cancer, and 218 control individuals. Groups were matched for age, body mass index, and menopausal status. The quality of diet was assessed using Brazilian Healthy Eating Index Revised (BHEI-R) and its components. Food consumption was measured through three 24-h dietary recalls and assessed using the NDS-R software. For statistical analyses, it was performed an adjusted logistic regression, estimation of the Odds Ratio (OR), and 95% confidence interval (95%CI), with a p-value <0.05. Results: The BHEI-R score, classified into quartiles, did not differ between groups in the lowest quartile of diet quality (p=0.853). The components total cereals (p=0.038), saturated fat (p=0.039) and Gord_AA (fat, alcohol, and added sugar) (p=0.023) had higher scores among the case group. The scores for total fruits (p=0.010) and milk and dairy products (p=0.039) were higher among the control group. The BHEI-R components and the quality of diet were not associated with the outcome. Conclusion: Diet quality, assessed by the BHEI-R and its components, was not associated with breast cancer.

RESUMO Objetivo: Avaliar se a qualidade da dieta e seus componentes estão associados ao desenvolvimento de câncer de mama. Métodos: Trata-se de estudo caso-controle com a participação de 332 mulheres, sendo 114 casos e 218 controles. Os grupos foram pareados por idade, índice de massa corporal e estado menopausal. A qualidade da dieta foi avaliada pelo Índice de Qualidade da Dieta Revisado (IQD-R) e seus componentes. O consumo alimentar foi mensurado por meio da aplicação de três recordatórios alimentares de 24 horas e analisados no software NDS-R. Foi realizada regressão logística ajustada, estimativa de odds ratio (OR) e intervalo de confiança de 95% (IC95%), com valor de p<0,05. Resultados: A pontuação do IQD-R, classificada em quartis, não diferiu entre os grupos no quartil inferior de qualidade da dieta (p=0,853). Os componentes cereais totais (p=0,038), gordura saturada (p=0,039) e Gord_AA (gordura, álcool e açúcar de adição) (p=0,023) tiveram maior pontuação no grupo caso. Já a pontuação de frutas totais (p=0,010) e leites e derivados (p=0,039) foi maior no grupo controle. Os componentes do IQD-R, assim como a qualidade da dieta, não se associaram ao desfecho investigado. Conclusão: A qualidade da dieta, avaliada pelo IQD-R e os seus componentes, não se associou ao câncer de mama.

Peri-implant health after supportive mucositis therapy is associated with increased levels of FGF-2.

This study aimed to analyze Fibroblast Growth Factor-2 (FGF-2) levels in the peri-implant crevicular fluid throughout supportive mucositis therapy. Twenty-six participants with Branemark protocol prosthesis were divided into two groups: the control group, characterized by healthy peri-implants, and the mucositis group, presenting a diagnosis of peri-implant mucositis. All participants underwent clinical examination, radiographic analysis, prosthesis removal, and non-invasive peri-implant therapy (mechanical debridement associated with chlorhexidine 0.12%) during a period of 36 days divided into three intervals. Peri-implant crevicular fluid samples were collected at each interval in order to analyze FGF-2 levels by immuno-enzymatic assay. The control and mucositis groups showed difference in keratinized mucosa. The smaller the range of keratinized mucosa the higher susceptibility of peri-implant mucositis. Throughout the treatment intervals, participants were diagnosed in different groups indicating whether or not the non-invasive therapy was able to treat peri-implant mucositis. There was a significant difference of FGF-2 levels between groups, with the higher FGF-2 levels in the control group (p=0.01). After supportive therapy, the mucositis group showed significantly increased FGF-2 levels (p<0.01) compared to initial levels. After 36 days of supportive therapy, there was a reduction of peri-implant mucositis from 70% to 23%. Clinical and laboratory outcomes showed a clear correlation since FGF-2 levels increased after 36 days. It was concluded that the therapy protocol was effective and promoted a regenerative reaction and FGF-2 can be considered a future target for peri-implant mucositis understanding.

Modulation of Epithelial Mesenchymal Transition after AGTR-1 Gene Edition by Crispr/Cas9 and Losartan Treatment in Mammary Tumor Cell Line: A Comparative Study between Human and Canine Species.

Breast cancer is the most prevalent tumor type among women and female dogs. Tumor malignancy is characterized by the epithelial-to-mesenchymal transition (EMT) which leads to the metastasis formation. The inhibition of angiotensin II type I receptor (AGTR1) by an antagonist such as losartan can suppress angiogenesis, consequently contributing to the metastasis control. The aim of this study was to analyze the capacity of losartan and AGTR-1 gene edition to modulate the EMT process in triple negative/metastatic mammary tumor cells, compared to existing treatment protocols such as carboplatin. The cell lines CF41.Mg and MDA-MB-468, were cultured and treated with carboplatin, losartan, or submitted to AGTR-1 gene edition by CRISPR/Cas9. EMT markers and PARP-1 protein and gene expression were evaluated by immunofluorescence or immunocytochemistry and qRT-PCR, respectively. Cell migration capacity was also evaluated. For CF41.Mg and MDA-MB-468 cell lines, there was an increase in E-cadherin and a decrease in N-cadherin and PARP-1 protein and gene expression after treatment with carboplatin, losartan, both in combination and after AGTR-1 gene edition. There was a decrease in VEGF and PARP-1 protein and gene expression after AGTR-1 gene edition. Moreover, in both lines, reduction in invasion rate was observed after all treatments. Our data suggest that losartan and the gene edition of AGTR-1 by CRISPR/Cas9 were able to block the DNA repair and control the EMT process, such as carboplatin. The results in the canine species are unprecedented, as there are no data in the literature that demonstrate the action of losartan in this tumor type.

Liquid Biopsy as a Diagnostic and Prognostic Tool for Women and Female Dogs with Breast Cancer.

INTRODUCTION: Breast cancer (BC) is the malignant neoplasm with the highest mortality rate in women and female dogs are good models to study BC. OBJECTIVE: We investigated the efficacy of liquid biopsy to detect gene mutations in the diagnosis and follow-up of women and female dogs with BC. MATERIALS AND METHODS: In this study, 57 and 37 BC samples were collected from women and female dogs, respectively. After core biopsy and plasma samples were collected, the DNA and ctDNA of the tumor fragments and plasma were processed for next generation sequencing (NGS) assay. After preprocessing of the data, they were submitted to the Genome Analysis ToolKit (GATK). RESULTS: In women, 1788 variants were identified in tumor fragments and 221 variants in plasma; 66 variants were simultaneously detected in tumors and plasma. Conversely, in female dogs, 1430 variants were found in plasma and 695 variants in tumor fragments; 59 variants were simultaneously identified in tumors and plasma. The most frequently mutated genes in the tumor fragments of women were USH2A, ATM, and IGF2R; in female dogs, they were USH2A, BRCA2, and RRM2. Plasma of women showed the most frequent genetic variations in the MAP3K1, BRCA1, and GRB7 genes, whereas plasma from female dogs had variations in the NF1, ERBB2, and KRT17 genes. Mutations in the AKT1, PIK3CA, and BRIP genes were associated with tumor recurrence, with a highly pathogenic variant in PIK3CA being particularly prominent. We also detected a gain-of-function mutation in the GRB7, MAP3K1, and MLH1 genes. CONCLUSION: Liquid biopsy is useful to identify specific genetic variations at the beginning of BC manifestation and may be accompanied over the entire follow-up period, thereby supporting the clinicians in refining interventions.

Peri-implant health after supportive mucositis therapy is associated with increased levels of FGF-2

Abstract This study aimed to analyze Fibroblast Growth Factor-2 (FGF-2) levels in the peri-implant crevicular fluid throughout supportive mucositis therapy. Twenty-six participants with Branemark protocol prosthesis were divided into two groups: the control group, characterized by healthy peri-implants, and the mucositis group, presenting a diagnosis of peri-implant mucositis. All participants underwent clinical examination, radiographic analysis, prosthesis removal, and non-invasive peri-implant therapy (mechanical debridement associated with chlorhexidine 0.12%) during a period of 36 days divided into three intervals. Peri-implant crevicular fluid samples were collected at each interval in order to analyze FGF-2 levels by immuno-enzymatic assay. The control and mucositis groups showed difference in keratinized mucosa. The smaller the range of keratinized mucosa the higher susceptibility of peri-implant mucositis. Throughout the treatment intervals, participants were diagnosed in different groups indicating whether or not the non-invasive therapy was able to treat peri-implant mucositis. There was a significant difference of FGF-2 levels between groups, with the higher FGF-2 levels in the control group (p=0.01). After supportive therapy, the mucositis group showed significantly increased FGF-2 levels (p<0.01) compared to initial levels. After 36 days of supportive therapy, there was a reduction of peri-implant mucositis from 70% to 23%. Clinical and laboratory outcomes showed a clear correlation since FGF-2 levels increased after 36 days. It was concluded that the therapy protocol was effective and promoted a regenerative reaction and FGF-2 can be considered a future target for peri-implant mucositis understanding.

Resumo Este estudo teve como objetivo analisar os níveis de FGF-2 no fluido crevicular peri-implantar durante a terapia de suporte da mucosite. Vinte e seis participantes com prótese protocolo Branemark foram divididos em dois grupos: o grupo controle, caracterizado por saúde peri-implanter, e o grupo mucosite, apresentando diagnóstico de mucosite peri-implantar. Todos os participantes foram submetidos a exame clínico, análise radiográfica, retirada da prótese e terapia não invasiva peri-implantar (debridamento mecânico associado à clorexidina 0,12%) durante um período de 36 dias, dividido em três intervalos. Amostras de fluido crevicular peri-implantar foram coletadas em cada intervalo para análise dos níveis de FGF-2, por ensaio imunoenzimático. Os grupos controle e mucosite não apresentaram diferença nos parâmetros clínicos, exceto para mucosa queratinizada. Ao longo dos intervalos de tratamento, os participantes foram diagnosticados em diferentes grupos, indicando se a terapia não invasiva era ou não capaz de tratar a mucosite peri-implantar. Houve diferença significativa dos níveis de FGF-2 entre os grupos, sendo os níveis de FGF-2 maiores no grupo controle (p = 0.01). Após a terapia de suporte, o grupo com mucosite apresentou níveis de FGF-2 significativamente aumentados (p <0.01) em comparação aos níveis iniciais. Após 36 dias de terapia de suporte, houve redução da mucosite peri-implantar de 70% para 23%. Os resultados clínicos e laboratoriais mostraram uma correlação clara, uma vez que os níveis de FGF-2 aumentaram após 36 dias. O protocolo de terapia foi eficaz e promoveu uma reação regenerativa. O FGF-2 pode ser considerado um alvo futuro para o tratamento da mucosite peri-implantar.

Ambiguity and Ambivalence: an Issue for the Subjective Dynamics in the Relation between Language and Affection.

This article stems from an interest taken in discussing the usage of the terms ambivalence and ambiguity, which are very present in Psychology's publications and savoir faire. It is important to reiterate that in common sense and even in scientific publications these terms are often used as synonyms or notions of little conceptual delimitation. The relevance of such differentiation is proposed once these notions participates of the emergence of the new in human subjective experience, and, in a methodological approach, ambiguity and ambivalence are dimensions that leads the researcher goes beyond a repetitive sterile description of the subject's speech, moving towards new perspectives of the psychological data. This paper aims to retrieve the qualifying power of such notions by making a broader reflection on the functions of language in the production of interpretive realities. We also propose to bring up a reflection about ambiguity in the construction of meaning and to reiterate ambivalences as inherent to human nature, its affective record and the process of human becoming. As a way to explain the proposed themes, we will analyse an excerpt from the documentary "Últimas Conversas", produced by the Brazilian filmmaker Eduardo Coutinho, in which high school students from public state schools in Rio de Janeiro tell their stories, speaking of dreams and shared challenges. The character Rafaela was selected for this article because of the emergence of unspeakable emotions from her narrative about an expected future as a promise of reconciliation with the alterity of her life story.

Creativity and Fiction: Interpretative Horizons on the Emergence of the New in the Relationship Between Individual and Culture.

This article aims to establish, in the light of Semiotic-Cultural Constructivism in Psychology, a contribution to the research of creative processes through a reflection on the emergence of the new in the relationship between self-other-world. It is intended to advance in the classic approaches to creativity, by focusing on the unusual and ambiguous, affective-singularizing and, simultaneously, everyday-cultural face of the perspective of the possible and the new in the course of human action. In this way, the article focuses on fiction as a psychic reality that participates in the intersubjective field inherent to creative dynamics, as well as addresses affectivity in the Boeschian grammar from the place of the ambivalence and the dynamics between myths and fantasms in the forms of meaning construction in the face of disturbing experiences and uncertainty about the future. As an interpretive exercise, this text discusses a comic strip by a pair of elementary school students about a character who studies in a school where nothing was prohibited. The discussion of the data seeks to broaden the reading about the ways of fictionalizing the lived experience, pervasive to the everyday plot of the self, and its relationship with creativity in the future of human action.

Medidas emergenciais para a População em Situação de Rua: enfrentamento da pandemia e seus efeitos

A partir de março de 2020, quando da eclosão e intensificação dos efeitos da pandemia da Covid-19 no Brasil, foi possível identificar iniciativas governamentais para assistir aos grupos mais vulneráveis diante das necessidades de subsistência, manutenção da saúde, isolamento e distanciamento social, como transferência direta de renda, isenção de tarifas e distribuição de alimentos, itens de higiene e equipamentos de proteção individual. Também foram notificadas ações, ainda mais incipientes, de isolamento de idosos e outras pessoas de grupos de risco ­ como moradores de residências adensadas ­ em abrigos provisórios (Calmon, 2020; Observatório das Desigualdades, 2020). Diante de todas essas emergências, a atenção à população em situação de rua (PSR) consegue congregar toda a sorte de dramas e demandas, não raro subestimados e naturalizados nas grandes cidades. A necessidade de isolamento social e higiene para aqueles que não têm sequer moradia (ou que dispõem de residências provisórias coletivas) e a limitação repentina e severa dos já precários meios de sobrevivência (doações e pequenos serviços) aprofundam o abismo social que esse grupo vivencia. Este texto vem identificar as principais iniciativas adotadas pelos gestores municipais voltadas à PSR no contexto da crise sanitária e de seus efeitos. Busca-se, aqui, sintetizar e atualizar os achados de pesquisa relatados na Nota Técnica no 74, População em Situação de Rua em Tempos de Pandemia: um levantamento de medidas municipais emergenciais (Silva, Natalino e Pinheiro, 2020), incorporando aspectos não explorados neste primeiro documento e, por sua vez, apenas referenciando outros itens que foram melhor abordados inicialmente.

População em situação de rua em tempos de pandemia: um levantamento de medidas municipais emergenciais / Nota Técnica n. 74 (Disoc): População em situação de rua em tempos de pandemia: um levantamento de medidas municipais emergenciais / Português

Identifica as principais iniciativas municipais em curso para o enfrentamento da necessidade de isolamento social e higiene para quem não tem sequer moradia, discorre sobre a qualidade, quantidade e oportunidade das ações realizadas, bem como sugere recomendações para sua implementação ou aprimoramento. Para tanto, foi realizada pesquisa documental em sites governamentais sobre tais iniciativas tendo como escopo de análise as capitais das regiões Nordeste e Sudeste. Adicionalmente, foram analisadas as percepções de atores-chave sobre o tema por meio de entrevistas semiestruturadas com gestoras e gestores, representantes do Judiciário e da sociedade civil, assim como pesquisadores na área das políticas públicas para a população de rua.

O financiamento federal dos serviços socioassistenciais no contexto da Covid-19 / Nota Técnica n. 80 (Disoc): O financiamento federal dos serviços socioassistenciais no contexto da Covid-19 / Português

O foco desta nota técnica são as ações tomadas no âmbito federal para garantir a cobertura e a expansão das ofertas socioassistenciais neste contexto de forte crescimento na demanda pelas proteções sociais. Também aborda o cofinanciamento federal do Sistema Único de Assistência Social (Suas) no contexto da Covid-19, efetuado por meio da destinação de recursos extraordinários transferidos pelo Fundo Nacional de Assistência Social (FNAS) aos respectivos fundos dos entes federativos. . Nesse sentido, apresenta as portarias que operacionalizaram os recursos destinados aos serviços de proteção social no âmbito do Suas, destacando a importância desses recursos, bem como os entraves para garantir a efetividade e o alcance dos objetivos ao qual se propõem.

A Wittgensteinian Comment on "Psychology: A Giant with Feet of Clay" A Question from Research on Creativity.

The present comment of the paper by Zagaria, Andò and Zennaro (2020) invests in the possible pragmatic entry of language in the problem of Psychology as a scientific enterprise, concerning the impossibility of consensus on its key constructs/concepts, and, consequently, the little cumulative capacity of the knowledge produced. Thus, the necessary discussion on the ambiguity, the cloudiness of the fundamental concepts of Psychology are reflected through the contributions of Wittgenstein II (2009) and the neopragmatism of Rorty (1999, 1995). Rorty offers a contemporary landscape on the purpose of knowledge production through his propositions on the relationship among truth, ethics and science in the humanities. The psychology of creativity is placed in the discussion as a field that well illustrate how the diversity of language games in Psychology reflects ethical perspectives in dealing with the phenomena, in this case related to the emergence of novelty, and the Rortian ironist reading on the relationship between objectivity and solidarity.

As transferências monetárias federais de caráter assistencial em resposta à Covid-19: mudanças e desafios de implementação / Nota Técnica n. 72 (Disoc): As Transferências monetárias federais de caráter assistencial em resposta à Covid-19: mudanças e desafios de implementação / Português

A presente nota técnica tem o objetivo de abordar as medidas federais implantadas como resposta à pandemia da Covid-19 relativas às transferências monetárias de caráter assistencial, quais sejam: Benefício de Prestação Continuada (BPC), Programa Bolsa Família (PBF/Bolsa Família) e Auxílio Emergencial.

Proteção social aos mais vulneráveis em contexto de pandemia: algumas limitações práticas de auxílio emergencial e a adequação dos benefícios eventuais como instrumento complementar de política socioassistencial / Nota Técnica n. 67 (Disoc): Proteção social aos mais vulneráveis em contexto de pandemia: algumas limitações práticas de auxílio emergencial e a adequação dos benefícios eventuais como instrumento complementar de política socioassistencial / Português

Esta nota técnica busca contribuir com os esforços de proteção social neste contexto de pandemia, Apresentando uma análise de vulnerabilidades descobertas e propondo soluções. Relaciona algumas vulnerabilidades particularmente pungentes ­ desnutrição, desabrigo, ausência de registro civil, exclusão digital, nascimento e morte ­ a algumas limitações práticas do auxílio emergencial. Estas limitações incluem questões de: i) acesso a documentos e tecnologias da informação (TIs); ii) celeridade no atendimento a necessidades básicas; e iii) insuficiência do auxílio para cobrir alguns riscos sociais particulares.