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Background: Coronavirus disease 2019 (COVID-19) vaccination programs in Europe began in December 2020, and as the number of vaccinated people increased, more information emerged about the possible side effects of vaccines. Recently, some reports appeared around the association of adverse reactions following soft-tissue filler injections and the COVID-19 vaccines. This fact raised the concerns of esthetic practitioners regarding the possibility of the association of the COVID-19 vaccine and adverse effects in other esthetic treatments. Many of us wonder if botox injection, biostimulation, or other procedure could trigger the same or other adverse reactions after the COVID-19 vaccination. Many colleagues postpone esthetic treatments, canceling the appointments. Objective: The objective of our investigation was to understand if any adverse reactions have been observed in the patients who underwent threads implantation before and after the vaccination. Materials and Methods: Four medical centers have collected the data of the patients treated with absorbable threads before the vaccination and after vaccination for COVID-19. The dossiers of 190 patients with a mean age of 50.4 years were evaluated. Three questionnaires were administered 1 week, 1 month, and 3 months after thread implantation. Results: There were no adverse reactions in the groups of patients under monitoring. Only one patient presented signs of inflammation and infection, but they are more probably attributable to the contamination during thread insertion. Conclusions: No patients treated with absorbable threads developed adverse events in relation to the COVID-19 vaccine. The only case of inflammation is attributable probably to the contamination of the thread during the procedure.
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Purpose: We propose a new method of genital rejuvenation based on absorbable thread insertion. In this study, we aimed to assess the safety and efficacy of particular absorbable threads made of P (LA/CL), the so-called Nano Spring 7, for vulvar rejuvenation. Patients and Methods: The study was conducted in two parts: the first by anatomical dissection and the second by clinical study. The first part of the study clarified safety and efficacy of thread insertion in this anatomical area. During the second part, 19 patients underwent Nano Spring 7 absorbable thread insertion in the subcutaneous layer of the labia majora to improve esthetic parameters and were followed up after 7, 30, 90, and 180 days. We evaluated outcomes using four different patients' questionnaires and one investigator's questionnaire. Results: The anatomical dissection defined the correct anatomical layer of threads implantation and the subcutaneous structures allowing for the thread anchoring. All the patients completed the study. The patients' and investigators' subjective evaluations during follow-up and at the end of the study were very positive. All the patients showed a decrease in discomfort sensations related to the labia majora conditions and aesthetic improvement in the vulvar area and recommended the treatment to their friends. Conclusion: The use of absorbable threads is an innovative, safe minimally invasive approach to genital rejuvenation.
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BACKGROUND: The lips and perioral area play a crucial role in facial aesthetics. Signs of aging, such as wrinkles, decreased muscle tone, and thinning skin, frequently appear first in this anatomical area and, subsequently, in other areas. This may explain why the lips and perioral area are frequently requested focus areas for aesthetic treatments that retain the client’s natural features. AIMS: To assess the safety and efficacy of the rejuvenation of the perioral area with an injectable product containing high-molecular-weight (HMW) native hyaluronic acid (HA) and a cluster of amino acids (AAs). PATIENTS/METHODS: In this open-label observational study, 37 female patients underwent 3 monthly sessions of intradermal injections with HMW HA gel with a cluster of AAs. Follow-up investigations were performed after 30, 60, and 180 days. Outcomes were evaluated subjectively using a patient questionnaire, the Global Aesthetic Improvement Scale (GAIS) questionnaire, and objectively using a 3D photosystem. RESULTS: All patients completed the study. The subjective evaluations made by patients and by the investigator during follow up and at the end of the study were positive, and all patients showed improvement in the perioral area. The objective evaluation showed a statistically significant improvement in pores condition and wrinkles. CONCLUSIONS: The protocol for rejuvenation of the perioral area with injections of HMW HA gel and AA is safe and effective. J Drugs Dermatol. 2022;21(9):968-973.doi:10.36849/JDD.6875.