Asunto(s)
Labio Leporino , Fisura del Paladar , Anomalías Craneofaciales , Humanos , Labio , PárpadosAsunto(s)
Humanos , Masculino , Anciano de 80 o más Años , Antineoplásicos/efectos adversos , Antagonistas de Receptores Androgénicos/efectos adversos , Exantema/inducido químicamente , Antineoplásicos/uso terapéutico , Antagonistas de Receptores Androgénicos/uso terapéutico , Neoplasias de la Próstata/tratamiento farmacológicoAsunto(s)
Humanos , Masculino , Anciano de 80 o más Años , Antineoplásicos/efectos adversos , Antagonistas de Receptores Androgénicos/efectos adversos , Exantema/inducido químicamente , Antineoplásicos/uso terapéutico , Antagonistas de Receptores Androgénicos/uso terapéutico , Neoplasias de la Próstata/tratamiento farmacológicoAsunto(s)
Humanos , Femenino , Persona de Mediana Edad , Hipopigmentación/inducido químicamente , Dermatosis del Pie/inducido químicamente , Glucocorticoides/efectos adversos , Triamcinolona/efectos adversos , Inyecciones Intralesiones , Glucocorticoides/administración & dosificación , Triamcinolona/administración & dosificación , Atrofia/inducido químicamenteAsunto(s)
Humanos , Femenino , Persona de Mediana Edad , Hipopigmentación/inducido químicamente , Dermatosis del Pie/inducido químicamente , Glucocorticoides/efectos adversos , Triamcinolona/efectos adversos , Inyecciones Intralesiones , Glucocorticoides/administración & dosificación , Triamcinolona/administración & dosificación , Atrofia/inducido químicamenteRESUMEN
No disponible
Asunto(s)
Humanos , Masculino , Anciano , Liquen Plano/patología , Lesiones Precancerosas/patología , Hiperplasia , Epidermis/patologíaRESUMEN
No disponible
Asunto(s)
Humanos , Masculino , Femenino , Anciano , Actitud Frente a la Salud , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/clasificación , Infecciones por Coronavirus/epidemiología , Neumonía Viral/epidemiología , Tiempo de TratamientoAsunto(s)
Angiografía Coronaria , Dermatosis de la Mano/diagnóstico , Dermatosis de la Mano/virología , Herpes Zóster/diagnóstico , Enfermedades Cutáneas Virales/diagnóstico , Cardiomiopatía de Takotsubo , Anciano , Femenino , Dermatosis de la Mano/complicaciones , Herpes Zóster/complicaciones , Humanos , Dolor/etiología , Enfermedades Cutáneas Virales/complicacionesAsunto(s)
Liquen Plano , Neoplasias Cutáneas , Estudios de Seguimiento , Humanos , Liquen Plano/diagnósticoRESUMEN
BACKGROUND: Digital dermoscopy (DD) has been found to improve the accuracy of melanoma diagnosis in high-risk patients. A 2-step approach combining DD and total-body photography (TBP) can facilitate the detection of new lesions or early macroscopic changes in existing lesions. OBJECTIVES: The aim of this study was to determine the number of biopsies needed to diagnose melanoma and to describe the clinical and dermoscopic characteristics of melanoma diagnosed in patients with pigmented lesions under follow-up with DD and TBP. PATIENTS AND METHODS: Retrospective study of 152 patients with a high risk of melanoma who were followed using a 2-step digital approach at Hospital del Mar in Barcelona, Spain, between 2002 and 2016. We analyzed the characteristics of pigmented lesions excised after macroscopic changes were detected by periodic DD and TBD. RESULTS: Biopsy results of 99 lesions (84 dysplastic nevi, 13 melanomas, and 2 compound melanocytic nevi) showed a ratio of benign melanocytic lesions to melanomas of 1:6.6. The mean Breslow thickness was 0.19 mm. Macroscopic changes were significantly more common in melanomas than in melanocytic nevi (P = 0.018). Dermoscopic findings associated with melanoma were asymmetric growth and focal structural changes (P < 0.001). The specific features associated with a diagnosis of melanoma were asymmetry (P < 0.001), a reverse pigment network (P = 0.011), atypical globules (P = 0.011), and polymorphous vessels (P = 0.045). CONCLUSIONS: TBP follow-up is a useful tool for the early diagnosis of melanoma. In our series, 50% of melanomas diagnosed during digital follow-up were detected by observation of a new lesion via TBP mapping or macroscopic changes in an existing lesion. Dermoscopic follow-up is essential in patients at high risk for melanoma as both melanocytic nevi and melanoma show a range of specific dermoscopic features, and a diagnosis of melanoma can only be based on a record of changes in the appearance of lesions during follow-up.