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1.
Curr Issues Personal Psychol ; 12(1): 20-29, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38756196

RESUMEN

BACKGROUND: Previous studies have shown that personality traits (i.e., openness to experience, conscientiousness, and agreeableness) relate to prejudicial attitudes. However, one of the aspects of prejudice is social distance; its association with personality traits was overlooked by previous studies. Therefore, this study examines the connection between the Big Five personality traits and social distance toward certain social groups. PARTICIPANTS AND PROCEDURE: Participants from the general population were recruited through leaflets, the institutional webpage, Facebook, and through the project recruitment website and assessed via paper-and-pencil or online form. A total of 214 participants were included (of whom 68.2% were women and the mean age was 32.65, SD = 11.27, range 18-72) who completed the Bogardus Social Distance Scale and the 44-item Big Five Inventory questionnaire. RESULTS: The results showed a relationship between social distance, agreeableness, and openness to experience. Agreeableness seems to lower the social distance toward all studied groups. In comparison, openness to experience seems to lower the social distance towards groups that evoke more polarized attitudes in the majority (e.g., migrants). Furthermore, the influence of demographic characteristics (i.e., age, education level, and gender) is also significant. CONCLUSIONS: This study shows that personality is significantly related to social distancing and expression of prejudicial attitudes. In particular, agreeableness and openness to experience have different effects on social distance and attitudes towards different groups. Further implications are discussed.

2.
Glob Ment Health (Camb) ; 11: e47, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38690571

RESUMEN

In addition to the loss of life, Russian aggression against Ukraine, which began in February 2022, also brings interpersonal losses resulting from the need to emigrate. Parallel to the fighting men, women bear most of the burden of caring for the family. Using in-depth interviews supplemented by questions about adverse childhood experiences and administration of The Centrality of Events Scale and the PTSD Checklist - PCL-5 with 43 Ukrainian women (18-60 years old), we analyzed adaptation to the situation of emigration and the association of their war and earlier experiences with the level of traumatization. Women were interviewed shortly after emigration to the Czech Republic (3-42 week afterward). High levels of adverse childhood experiences and post-traumatic stress symptoms were found. The war was perceived as a currently negative central event associated with traumatic stress symptoms, and 79% of the sample expressed the opinion that the war had changed them. The results of this study suggest an intertwining of previous life experiences with the current need and ability to adapt.

3.
Front Psychol ; 15: 1310238, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38445052

RESUMEN

Introduction: The Communist Party's reign in Czechoslovakia (1948-1989) saw the persecution of thousands of individuals. The State Security campaign "Asanace" (meaning "sanitation") was conducted to expel critics of the regime from the country using psychological and physical terror. Although stories of dissidents are frequently presented in public spaces, little is known about the experiences of their children. Methods: To address this gap, we conducted interpretative phenomenological analyses of semi-structured in-depth interviews with five adult descendants of Czechoslovakian dissidents. Results: Our analyses revealed that while participants appreciated and were inspired by their parents' dissident activities, they tend to distance themselves from it in order not to live in their parents' shadow. Furthermore, for them, the "Asanace" campaign primarily meant emigration, which in turn affected their sense of self and (national) identity dispersion. Consequently, they experienced feelings of being uprooted and different. Furthermore, they faced challenges acculturating. However, they also recognized their resilience as being rooted in their migration experience and the legacy of their parents' dissidence. Discussion: By highlighting intergenerational differences and the impact of family legacy on individuals' strengths and weaknesses, this study contributes to our understanding of the psychological consequences of living in, escaping from and adjusting to life beyond oppressive regimes.

4.
Artículo en Inglés | MEDLINE | ID: mdl-38300473

RESUMEN

Otherness is a complex and polysemic notion that is conceptualized in both philosophy and psychology. The paper examines otherness as a universal phenomenon of the human psyche that manifests in relation to oneself and interpersonal relationships with others. Philosophical ideas, including those of Hegel, Lévinas and Waldenfels, are introduced as providing essential theoretical background for psychological studies of otherness. The psychological section deals with otherness from various perspectives, with emphasis on internal processes of an individual, drawing on theories within psychoanalytical and intrapsychic traditions, as well as the intersection of otherness and identity. Otherness is introduced as a variable influencing complex individual and social processes, such as the perception of individuals and groups. Finally, a taxonomy of otherness is proposed that reflects the multifaceted nature of the concept and could help navigate the existing literature as well as guide new studies.

5.
Hist Psychol ; 27(2): 178-198, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38421767

RESUMEN

The study examines the development of psychology in former Czechoslovakia during the period of "normalization" (1968-1989) and the challenges it faced under the communist regime. The restricted connection to Western psychology and the regime's control over all aspects of human activity negatively influenced the continuity of development in psychology. The regime demanded conformity, leaving individuals, including psychologists, in recurring states of internal conflict and intellectual discomfort when deciding how much to compromise in their personal and professional lives. The study identifies three groups of psychologists based on their adaptability to regime demands. The first group consists of those who aligned themselves with the regime, allowing them to hold positions of leadership and shape the conceptualization of the field. The second group comprises individuals who actively opposed the regime, facing significant limitations in their educational and career opportunities, and mostly being forced to leave the profession. The third group of psychologists belongs to the apolitical gray zone. A significant portion of individuals in this largest group passively complied with established norms and constraints, accepting the restrictions imposed on the development of Czechoslovak psychology. Fortunately, thanks to the persistent efforts of the proactive members of the gray zone and their willingness to endure significant discomfort, an even deeper decline of psychology during the normalization period was prevented. The study provides insights into the topics of education, research, Western influences, and adaptation to the communist regime within Czechoslovak psychology, illuminating the intricacies of living in that historical period. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Asunto(s)
Individualidad , Psicología , Checoslovaquia , Psicología/historia , Humanos , Historia del Siglo XX , Conformidad Social , Comunismo/historia
6.
Sci Rep ; 13(1): 13835, 2023 08 24.
Artículo en Inglés | MEDLINE | ID: mdl-37620426

RESUMEN

This study focuses on hippocampal and amygdala volume, seed-based connectivity, and psychological traits of Holocaust survivors who experienced stress during prenatal and early postnatal development. We investigated people who lived in Central Europe during the Holocaust and who, as Jews, were in imminent danger. The group who experienced stress during their prenatal development and early postnatal (PreP) period (n = 11) were compared with a group who experienced Holocaust-related stress later in their lives: in late childhood, adolescence, and early adulthood (ChA) (n = 21). The results of volumetry analysis showed significantly lower volumes of both hippocampi and the right amygdala in the PreP group. Seed-based connectivity analysis revealed increased connectivity from the seed in the right amygdala to the middle and posterior cingulate cortex, caudate, and inferior left frontal operculum in the PreP group. Psychological testing found higher levels of traumatic stress symptoms (TCS-40) and lower levels of well-being (SOS-10) in the PreP group than in the ChA group. The results of our study demonstrate that extreme stress experienced during prenatal and early postnatal life has a profound lifelong impact on the hippocampus and amygdala and on several psychological characteristics.


Asunto(s)
Holocausto , Niño , Adolescente , Femenino , Embarazo , Humanos , Adulto , Hipocampo , Vitaminas , Amígdala del Cerebelo , Sobrevivientes
7.
Personal Ment Health ; 16(4): 319-330, 2022 11.
Artículo en Inglés | MEDLINE | ID: mdl-36204774

RESUMEN

The relationship between negative attitudes and psychopathology is not yet clear. The current shift to a dimensional approach to mental disorders, as reflected in both the DSM-5 and ICD-11 models of personality disorders, seems to enrich the traditional approach to study attitudes. This study investigates whether and how impairments in personality functioning are linked to attitudes toward minorities. A comparison of levels of impairment in global and Self and interpersonal personality functioning, negative attitudes, social distance, and racism was conducted in the sample of 127 adults from the general population group (n = 69) and a group of people with diagnosed personality disorders (n = 58). Differences between both groups were found. The personality disorders group showed higher impairment in personality functioning, scored higher on negative attitude measures, and was more prone to the blatant expression of attitudes than the general population. The association between attitudes and personality functioning did not fully reflect these trends. However, given the nature of differences, it is suspected that the proclivity to the blatant expression of negative attitudes could go beyond negative attitudes toward minorities themselves and reflect disorder-related characteristics, that is, more problematic and conflicted relationships with others in general.


Asunto(s)
Minorías Étnicas y Raciales , Personalidad , Adulto , Humanos , Actitud , Manual Diagnóstico y Estadístico de los Trastornos Mentales , Trastornos de la Personalidad/diagnóstico , Psicopatología , Racismo
8.
Front Behav Neurosci ; 16: 919217, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36133931

RESUMEN

Subjective wellbeing (SWB) is an important factor of global adjustment. Intergenerational satisfaction in seriously traumatized people has not been studied so far in homogenous populations of Central and Eastern Europe. This study focuses on the SWB in three generations of survivors living in the Czech Republic and Slovakia after World War II (WWII). The focal groups were Holocaust survivors (ages 71-95, n = 47), Holocaust survivors' children (ages 30-73, n = 86), and their grandchildren (ages 15-48, n = 88), and they were compared to aged-matched groups without Holocaust history. The first and second generation of Holocaust survivors scored significantly lower than the comparison groups in wellbeing, as measured using the Schwartz Outcome Scale-10 (SOS-10). There was no significant difference in life satisfaction in any of the three generations. Within the focal group, identification as Jewish or as also Jewish was comparable in all three generations of Holocaust survivors (74% in the first, 79% in the second, and 66% in the third generation). Holocaust survivors declaring Jewish identity reported lower SWB compared to survivors declaring other than Jewish identity. The focal group generated more national identities than comparisons. The outcomes are discussed in the context of the history of Central and Eastern Europe.

9.
BMC Psychiatry ; 22(1): 315, 2022 05 04.
Artículo en Inglés | MEDLINE | ID: mdl-35508979

RESUMEN

BACKGROUND: The Alternative DSM-5 Model for Personality Disorders and the latest eleventh version of the International Classification of Diseases implement the level of impairment in self and interpersonal personality functioning (Level of Personality Functioning Scale - LPFS) as a core feature of personality pathology. However, some studies have indicated that personality functioning is also impaired in other mental disorders, but a more thorough exploration is missing. Thus, this study aims to develop profiles of levels of personality functioning in people with personality disorders and some other psychiatric diagnoses as well as without diagnosis. METHODS: One-hundred-forty-nine people participated in the study. They came from three groups - healthy controls (n = 53), people with personality disorders (n = 58), and people with mood and anxiety disorders (n = 38). The LPFS was assessed by the Semi-structured Interview for Personality Functioning DSM-5 (STiP-5.1). An optimal clustering solution using agglomerative hierarchical cluster analysis was generated to represent profiles of personality functioning. RESULTS: The two patient groups showed significantly higher levels of personality functioning impairment than healthy controls. People with personality disorders showed higher levels of impairment than the other groups. In addition, the clustering analysis revealed three distinct profiles of personality functioning. CONCLUSIONS: The impairment of personality functioning seems to be useful in the clinical assessment of other than personality disorders as well. As the resulting clustering profiles suggest, LPFS can be seen as an overall indicator of the severity of mental health difficulties and the presence of mental disorders symptoms. The LPFS provides valuable and detailed information about the individual's mental health and can thus serve as a broad basis for case formulation, treatment and therapy planning, and prognosis.


Asunto(s)
Trastornos de la Personalidad , Personalidad , Ansiedad , Trastornos de Ansiedad/diagnóstico , Análisis por Conglomerados , Manual Diagnóstico y Estadístico de los Trastornos Mentales , Humanos , Trastornos de la Personalidad/diagnóstico , Psicometría , Reproducibilidad de los Resultados
10.
J Trauma Stress ; 35(1): 159-167, 2022 02.
Artículo en Inglés | MEDLINE | ID: mdl-34352929

RESUMEN

The psychological consequences of trauma related to the Holocaust have been primarily studied in samples derived from Israel, North America, and Western Europe. Few studies have examined postcommunist countries in Central and Eastern Europe. The present study focused on three generations living in the Czech Republic and Slovakia after World War II (WWII): Holocaust survivors (71-95 years of age), their children (30-73 years of age), and their grandchildren (15-48 years of age). We compared scores on measures of posttraumatic stress symptoms (PTSS; the Posttraumatic Stress Disorder Checklist-Civilian Version) and posttraumatic growth (PTG; the Posttraumatic Growth Inventory) derived from three focal samples with scores from age-matched comparison participants. Higher PTSS scores emerged for Holocaust survivors in all generations, η2 P=.087 but only participants in the first generation reported higher PTG scores relative to the comparison group, with small effect sizes for the overall group differences, η2 P=.029 . These results are discussed in the historical and political context of postwar Czechoslovakia.


Asunto(s)
Holocausto , Crecimiento Psicológico Postraumático , Trastornos por Estrés Postraumático , Niño , República Checa , Holocausto/psicología , Humanos , Eslovaquia , Trastornos por Estrés Postraumático/psicología , Sobrevivientes/psicología
11.
Personal Ment Health ; 15(3): 198-207, 2021 08.
Artículo en Inglés | MEDLINE | ID: mdl-33818001

RESUMEN

The DSM-5 Alternative Model for Personality Disorders introduced a dimensional perspective on personality disorders and their assessment by measuring personality functioning in the following domains: Identity, Self-Direction, Empathy, and Intimacy. This study provides a replication of the psychometric evaluation of the Semi-Structured Interview for Personality Functioning DSM-5 (STiP-5.1) within a mixed clinical sample and a community sample. The sample consisted of 188 adults: 86 participants from the general population and 102 people from a mixed clinical sample. All participants completed the STiP-5.1 and Level of Personality Functioning Scale-Brief Form (LPFS-BF 2.0). Results showed good internal consistency (McDonald's ω = 0.89-0.94) and promising convergent validity (correlations with LPFS-BF 2.0 above 0.6) of the STiP-5.1. Its scores differentiated participants within the community sample from those in the mixed clinical sample with large effect sizes (rrb = 0.77-0.88). Moreover, the impairment in personality functioning was more pronounced in people with personality disorders than in other psychiatric disorders (medium effect size, rrb = 0.46-0.57), supporting the notion of a continuum of personality functioning impairment. The STiP-5.1 therefore offers an instrument with satisfactory psychometric properties for the assessment of personality functioning both for research and clinical practice.


Asunto(s)
Trastornos de la Personalidad , Personalidad , Adulto , República Checa , Manual Diagnóstico y Estadístico de los Trastornos Mentales , Humanos , Trastornos de la Personalidad/diagnóstico , Psicometría , Reproducibilidad de los Resultados
12.
Neurobiol Stress ; 14: 100318, 2021 May.
Artículo en Inglés | MEDLINE | ID: mdl-33869682

RESUMEN

BACKGROUND: We aimed to assess the lifelong impact of extreme stress on people who survived the Holocaust. We hypothesised that the impact of extreme trauma is detectable even after more than 70 years of an often complicated and stressful post-war life. METHODS: Psychological testing was performed on 44 Holocaust survivors (HS; median age 81.5 years; 29 women; 26 HS were under the age of 12 years in 1945) and 31 control participants without a personal or family history of the Holocaust (control group (CG); median 80 years; 17 women). Magnetic resonance imaging (MRI) using the 3T Siemens Prisma scanner was performed on 29 HS (median 79 years; 18 women) and 21 CG participants (median 80 years; 11 women). The MRI-tested subgroup that had been younger than 12 years old in 1945 was composed of 20 HS (median 79 years; 17 women) and 21 CG (median 80 years; 11 women). RESULTS: HS experienced significantly higher frequency of depression symptoms, posttraumatic stress symptoms, and posttraumatic growth, and lower levels of well-being. The MRI shows a lifelong neurobiological effect of extreme stress. The areas with reduced grey matter correspond to the map of the impact of stress on the brain structure: insula, anterior cingulate, ventromedial cortex including the subgenual cingulate/orbitofrontal cortex, temporal pole, prefrontal cortex, and angular gyrus. HS showed good adjustment to post-war life conditions.Psychological growth may contribute to compensation for the psychological and neurobiological consequences of extreme stress.The reduction of GM was significantly expressed also in the subgroup of participants who survived the Holocaust during their childhood. CONCLUSION: The lifelong psychological and neurobiological changes in people who survived extreme stress were identified more than 70 years after the Holocaust. Extreme stress in childhood and young adulthood has an irreversible lifelong impact on the brain.

13.
Front Psychol ; 11: 1344, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32714239

RESUMEN

Depression is a mental health condition for which individuals commonly seek treatment. However, depressive episodes often resolve on their own, even without treatment. One evolutionary perspective, the analytical rumination hypothesis (ARH), suggests that depression occurs in response to complex problems. According to this perspective, depressive symptoms promote analytical rumination, i.e., distraction-resistant thoughts about the causes of problems [causal analysis (CA)] and how they can be solved [problem-solving analysis (PSA)]. By helping individuals solve complex problems, analytical rumination may contribute to remission from depression. The aim of this study was to investigate (1) whether clinically-depressed individuals have more complex problems and engage in more CA and PSA than non-depressed and (2) the effects of CA and PSA on decreases in problem complexity, depressive symptoms, and remission from the depression. Samples of 85 patients were treated for depression with antidepressants and psychotherapy, and 49 healthy subjects were assessed three times over a 4-month period (at Weeks 1, 5, and 16). At each assessment, they completed measures of depression, analytical rumination, and problem complexity. Depressed individuals reported having more complex problems and engaging in more CA than non-depressed participants. The two groups engaged in a similar degree of PSA. Findings from a multiple regression suggested that more PSA at Week 1 was related to a decrease in depressive symptoms at Week 5, even after controlling for baseline depression, problem number, and complexity. PSA at Week 1 did not predict the remission after hospitalization or at follow-up; however, having less complex problems at the baseline made it more likely that a patient would later remit. Engaging in more CA or PSA at Week 1 did not affect perceived problem complexity at Week 5 or at follow-up. However, these findings were not statistically significant when influential observations (or outliers) were included in the analysis. Our findings suggest that PSA may contribute to a decrease in symptoms of depression over time. However, alleviations in problem complexity and remission might only be achieved if problems are initially less complex. Future directions involve exploring how PSA might contribute to decreases in depressive symptoms and other mechanisms underlying remission from depression.

15.
Front Genet ; 11: 87, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32211017

RESUMEN

Mitochondrial DNA copy number has been previously shown to be elevated with severe and chronic stress, as well as stress-related pathology like Major Depressive Disorder (MDD) and post-traumatic stress disorder (PTSD). While experimental data point to likely recovery of mtDNA copy number changes after the stressful event, time needed for full recovery and whether it can be achieved are still unknown. Further, while it has been shown that stress-related mtDNA elevation affects multiple tissues, its specific consequences for oogenesis and maternal inheritance of mtDNA has never been explored. In this study, we used qPCR to quantify mtDNA copy number in 15 Holocaust survivors and 102 of their second- and third-generation descendants from the Czech Republic, many of whom suffer from PTSD, and compared them to controls in the respective generations. We found no significant difference in mtDNA copy number in the Holocaust survivors compared to controls, whether they have PTSD or not, and no significant elevation in descendants of female Holocaust survivors as compared to descendants of male survivors or controls. Our results showed no evidence of persistence or inheritance of mtDNA changes in Holocaust survivors, though that does not rule out effects in other tissues or mitigating mechanism for such changes.

16.
PLoS One ; 14(11): e0221988, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31756184

RESUMEN

Many studies show that keeping cats and dogs has a positive impact on humans' physical and mental health and quality of life. The existence of this "pet phenomenon" is now widely discussed because other studies performed recently have demonstrated a negative impact of owning pets or no impact at all. The main problem of many studies was the autoselection-participants were informed about the aims of the study during recruitment and later likely described their health and wellbeing according to their personal beliefs and wishes, not according to their real status. To avoid this source of bias, we did not mention pets during participant recruitment and hid the pet-related questions among many hundreds of questions in an 80-minute Internet questionnaire. Results of our explorative study performed on a sample of 10,858 subjects showed that liking dogs has a weak positive association with quality of life. However, keeping pets, especially cats, and even more being injured by pets, were strongly negatively associated with many facets of quality of life. Our data also confirmed that infection by the cat parasite Toxoplasma had a very strong negative effect on quality of life, especially on mental health. However, the infection was not responsible for the observed negative effects of keeping pets, as these effects were much stronger in 1,527 Toxoplasma-free subjects than in the whole population. Any cross-sectional study cannot discriminate between a cause and an effect. However, because of the large and still growing popularity of keeping pets, the existence and nature of the reverse pet phenomenon deserve the outmost attention.


Asunto(s)
Gatos , Perros , Mascotas , Calidad de Vida , Toxoplasmosis/etiología , Heridas y Lesiones/etiología , Adulto , Animales , Gatos/microbiología , Estudios Transversales , Perros/microbiología , Femenino , Vínculo Humano-Animal , Humanos , Internet , Masculino , Curación Mental , Encuestas y Cuestionarios , Toxoplasma
17.
J Psychiatr Res ; 117: 7-14, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-31255955

RESUMEN

Telomeres, nucleoprotein structures at the ends of eukaryotic chromosomes, are crucial for the maintenance of genome integrity. While the lengths of telomeres at birth are determined genetically, many factors including environmental and living conditions affect the telomere lengths during a lifespan. In this context, extreme and long-term stress has been shown to negatively impact telomeres and their protective function, with even offspring being influenced by the stress experienced by parents. Using quantitative PCR, the relative lengths of telomeres of survivors of the Holocaust during World War II and two generations of their offspring were analyzed. These data were related to those of control groups, persons of comparable age without a strong life stress experience. In contrast to previous studies of other stress-exposed groups, the relative lengths of telomeres were comparable in groups of persons exposed to Holocaust-related stress and their progenies, and in control groups. Interestingly, shorter telomeres of Holocaust survivors of the age under 12 in the year 1945 compared to Holocaust survivors of the age above 12 were detected. Our results are discussed with respect to certain exceptionality of persons having been able to cope with an extreme stress more than 70 years ago and living to a very old age.


Asunto(s)
Adaptación Psicológica/fisiología , Hijos Adultos , Adultos Sobrevivientes de Eventos Adversos Infantiles , Envejecimiento/fisiología , Holocausto , Trastornos por Estrés Postraumático , Estrés Psicológico , Sobrevivientes , Homeostasis del Telómero/fisiología , Acortamiento del Telómero/fisiología , Adolescente , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Reacción en Cadena en Tiempo Real de la Polimerasa , Trastornos por Estrés Postraumático/metabolismo , Trastornos por Estrés Postraumático/fisiopatología , Estrés Psicológico/metabolismo , Estrés Psicológico/fisiopatología , Adulto Joven
18.
Genes Brain Behav ; 18(6): e12536, 2019 07.
Artículo en Inglés | MEDLINE | ID: mdl-30411505

RESUMEN

The genetic correlates of extreme impulsive violence are poorly understood, and there have been no studies that have systematically characterized a large group of affected individuals both clinically and genetically. We performed a genome-wide rare copy number variant (CNV) analysis in 281 males from four Czech prisons who met strict clinical criteria for extreme impulsive violence. Inclusion criteria included age ≥ 18 years, an ICD-10 diagnosis of Dissocial Personality Disorder, and the absence of an organic brain disorder. Participants underwent a structured psychiatric assessment to diagnose extreme impulsive violence and then provided a blood sample for genetic analysis. DNA was genotyped and CNVs were identified using Illumina HumanOmni2.5 single-nucleotide polymorphism array platform. Comparing with 10851 external population controls, we identified 828 rare CNVs (frequency ≤ 0.1% among control samples) in 264 participants. The CNVs impacted 754 genes, with 124 genes impacted more than once (2-25 times). Many of these genes are associated with autosomal dominant or X-linked disorders affecting adult behavior, cognition, learning, intelligence, specifically expressed in the brain and relevant to synapses, neurodevelopment, neurodegeneration, obesity and neuropsychiatric phenotypes. Specifically, we identified 31 CNVs of clinical relevance in 31 individuals, 59 likely clinically relevant CNVs in 49 individuals, and 17 recurrent CNVs in 65 individuals. Thus, 123 of 281 (44%) individuals had one to several rare CNVs that were indirectly or directly relevant to impulsive violence. Extreme impulsive violence is genetically heterogeneous and genomic analysis is likely required to identify, further research and specifically treat the causes in affected individuals.


Asunto(s)
Trastorno de Personalidad Antisocial/genética , Variaciones en el Número de Copia de ADN , Conducta Impulsiva , Violencia , Adolescente , Adulto , Anciano , Humanos , Masculino , Persona de Mediana Edad
19.
Front Psychiatry ; 9: 314, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30061846

RESUMEN

Several recent studies have demonstrated the association of cat-related injuries with major depression and with depressiveness in the general population. It was suggested that cat-scratch disease, the infection with the bacterium Bartonella henselae, can be responsible for the observed association. However, no direct evidence for the role of the Bartonella infection in this association has been published until now. In this preregistered case-controls study performed on 250 healthy subjects tested earlier for the presence of anti-Toxoplasma IgG antibodies, we searched for the positive association between presence of anamnestic anti-Bartonella IgG antibodies and depressiveness measured with Beck II inventory, depression subscale of neuroticism measured with N-70 questionnaire, and self-reported health problems. We found that that Bartonella seropositivity was positively correlated with Beck depression only in Toxoplasma-seronegative men and negatively correlated with health in Toxoplasma-seronegative women. Bartonella seropositivity expressed protective effects against Toxoplasma seropositivity-associated increased neuroticism in men while Toxoplasma-seropositivity expressed protective effects against Bartonella seropositivity-associated health problems in women. A comparison of the patterns of association of mental and physical health problems with Bartonella seropositivity and with reported cat-related injury suggests that different factor, possibly infection with different pathogen transmitted by cat related-injuries than the B. henselae, is responsible for the observed association of cat related-injuries with depressiveness and major depression. The existence of complex interactions between Bartonella seropositivity, Toxoplasma seropositivity, and sex also suggest that the effect of symbionts on the host's phenotype must by always studied in the context of other infections, and separately for men and women.

20.
Personal Ment Health ; 12(4): 281-297, 2018 11.
Artículo en Inglés | MEDLINE | ID: mdl-29952078

RESUMEN

To date, numerous studies have confirmed empirical relevance of the personality trait model defined in the Alternative DSM-5 Model for Personality Disorders. The supposed single-factor structure of its facets and general domains across various samples, however, has not been researched thoroughly. This study focused on evaluating the hypothesized unidimensional factor structure of the lower-order personality trait facets, as well as the validity of the higher-order domains. The Czech version of the Personality Inventory for DSM-5 (PID-5) was used in a sample of 351 community volunteers and 143 psychiatric patients. The fit of the model for 25 facets could not be replicated with the original PID-5, while a shortened version confirmed the single-factor structure of all facets and their relevance to the five proposed domains. The findings support unidimensional structure of the modified DSM-5 personality trait model and imply discussion of the utility of the proposed PID-5 version. Copyright © 2018 John Wiley & Sons, Ltd.


Asunto(s)
Manual Diagnóstico y Estadístico de los Trastornos Mentales , Modelos Psicológicos , Trastornos de la Personalidad/diagnóstico , Inventario de Personalidad , Personalidad , Adolescente , Adulto , Anciano , República Checa , Análisis Factorial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Psicometría , Adulto Joven
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