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Vopr Med Khim ; 35(4): 79-81, 1989.
Article Ru | MEDLINE | ID: mdl-2815684

Acid extract of bovine epiphyses was separated by means of gel filtration on Sephadex G-50 into two fractions: high and low molecular preparations. Estimation of biological activity of the acid extract and its polypeptide fractions, which was carried out using the procedure of antigonadotropic effect on preadolescent rat females, showed that the antigonadotropic effect was distinctly higher in the preparation free of high molecular substances.


Epiphyses/analysis , Tissue Extracts/analysis , Amino Acids/analysis , Animals , Cattle , Chromatography, Gel , Female , Ovary/drug effects , Rats , Tissue Extracts/pharmacology
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