Comparison of the Discrimination Performance of AI Scoring and the Brixia Score in Predicting COVID-19 Severity on Chest X-Ray Imaging: Diagnostic Accuracy Study.

BACKGROUND: The artificial intelligence (AI) analysis of chest x-rays can increase the precision of binary COVID-19 diagnosis. However, it is unknown if AI-based chest x-rays can predict who will develop severe COVID-19, especially in low- and middle-income countries. OBJECTIVE: The study aims to compare the performance of human radiologist Brixia scores versus 2 AI scoring systems in predicting the severity of COVID-19 pneumonia. METHODS: We performed a cross-sectional study of 300 patients suspected with and with confirmed COVID-19 infection in Jakarta, Indonesia. A total of 2 AI scores were generated using CAD4COVID x-ray software. RESULTS: The AI probability score had slightly lower discrimination (area under the curve [AUC] 0.787, 95% CI 0.722-0.852). The AI score for the affected lung area (AUC 0.857, 95% CI 0.809-0.905) was almost as good as the human Brixia score (AUC 0.863, 95% CI 0.818-0.908). CONCLUSIONS: The AI score for the affected lung area and the human radiologist Brixia score had similar and good discrimination performance in predicting COVID-19 severity. Our study demonstrated that using AI-based diagnostic tools is possible, even in low-resource settings. However, before it is widely adopted in daily practice, more studies with a larger scale and that are prospective in nature are needed to confirm our findings.

Differences in syntactic and semantic analysis based on machine learning algorithms in prodromal psychosis and normal adolescents.

Schizophrenia has the main symptom of psychosis which is characterized by speech incoherence due to thought process disturbance. Before schizophrenia, there is a prodromal phase of psychosis in adolescence. Early recognition of this phase is important to prevent the development of symptoms into a severe mental disorder. Machine learning technology can be used to predict thought process disturbance through syntactic and semantic analysis of speech. This study aims to describe the differences in syntactic and semantic analysis in prodromal psychosis and normal adolescents. The research subjects consisted of 70 adolescents aged 14-19 years which were divided into 2 groups. Based on the results of the Prodromal Questionnaire-Brief (PQ-B) Indonesian version, the subjects were split into two groups: prodromal and normal. All participants were voice-recorded during interviews using an open-ended qualitative questionnaire. Syntactic and semantic analysis was carried out on all data which amounted to 1017 phrase segments and classified by machine learning. This is the first study in Indonesia to compare the analysis of syntactic and semantic aspects in prodromal psychosis and normal adolescent populations. There were significant differences in syntactic and semantic analysis between groups of adolescents with prodromal psychosis and normal adolescents at the minimum value of coherence and frequency of use of nouns, personal pronouns, subordinate conjunctions, adjectives, prepositions, and proper nouns.