1.
Angew Chem Int Ed Engl
; : e202210508, 2022 Sep 09.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36082766
RESUMEN
The nickel catalyzed Suzuki-Miyaura-type coupling of aryl sulfamates and boronic acid derivatives enabled by temperature-controlled mechanochemistry via the development of a programmable PID-controlled jar heater is reported. This base-metal-catalyzed, solvent-free, all-under-air protocol was also scaled 200-fold using twin-screw extrusion technology affording decagram quantities of material.