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1.
Ann N Y Acad Sci ; 1450(1): 268-280, 2019 08.
Artículo en Inglés | MEDLINE | ID: mdl-31267542

RESUMEN

Although the proportion of anemia amenable to change varies by population, the World Health Organization (WHO) criteria used to describe the public health severity of anemia are based on population prevalences. We describe the importance of measuring iron and other etiologic indicators to better understand what proportion of anemia could be responsive to interventions. We discuss the necessity of measuring inflammation to interpret iron biomarkers and documenting anemia of inflammation. Finally, we suggest assessing nonmodifiable genetic blood disorders associated with anemia. Using aggregated results from the Global Burden of Disease 2016, we compare population prevalence of anemia with years lived with disability (YLD) estimates, and the relative contributions of mild, moderate, and severe anemia to YLD. Anemia prevalences correlated with YLD and the relative proportion of moderate or severe anemia increased with anemia prevalence. However, individual-level survey data revealed irregular patterns between anemia prevalence, the prevalence of moderate or severe anemia, and the prevalence of iron deficiency anemia (IDA). We conclude that although the WHO population prevalence criteria used to describe the public health severity of anemia are important for policymaking, etiologic-specific metrics that take into account IDA and other causes will be necessary for effective anemia control policies.


Asunto(s)
Anemia/diagnóstico , Salud Global , Hierro/sangre , Salud Pública , Anemia/sangre , Anemia/epidemiología , Humanos , Fase Preanalítica , Prevalencia
2.
Otolaryngol Clin North Am ; 51(3): 515-534, 2018 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-29773124

RESUMEN

The Global Burden of Disease (GBD) project provides longitudinal analysis of the global burden of otolaryngologic diseases by measuring the all-cause mortality, years of life lost, the years of life lived with disability, and disability-adjusted life years. Hearing loss burden is assessed overall and as sequelae of other diseases, such as otitis media or meningitis. Using these measures, we can appreciate the high prevalence and disability related to hearing loss globally. Other otolaryngologic diseases that contribute to the GBD include otitis media, cleft lip and palate, head and neck cancer, facial trauma, and oral disorders.


Asunto(s)
Costo de Enfermedad , Personas con Discapacidad/estadística & datos numéricos , Carga Global de Enfermedades/tendencias , Salud Global , Enfermedades Otorrinolaringológicas/mortalidad , Pérdida Auditiva/epidemiología , Humanos , Mortalidad , Otolaringología , Enfermedades Otorrinolaringológicas/clasificación , Años de Vida Ajustados por Calidad de Vida , Factores de Riesgo
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