RESUMEN
BACKGROUND: The hemostatic system is complex and evolves continuously since gestation and well into the adult years, in a process known as "developmental hemostasis." DATA SOURCES: A comprehensive review was performed after an extensive literature search on PubMed/MEDLINE concerning developmental hemostasis during the neonatal period. Relevant cross references were also included. RESULTS: Although part of a system, each component of the hemostatic system evolves differently, with many displaying both quantitative and qualitative age-related differences. This leads to drastic disparities between the coagulation system of neonates and both other children's and adults', while still maintaining a generally balanced and physiological hemostasis. The motives behind this process remain to be fully elucidated but may be, at least in part, related to non-hemostatic factors. CONCLUSIONS: Knowledge regarding "developmental hemostasis" is essential for everyone caring for newborns or even children in general and in this review, we describe each hemostatic system component's neonatal characteristics and age-related progression as well as explore some of the possible physiological motives behind the process.
Asunto(s)
Coagulación Sanguínea , Hemostasis , Adulto , Niño , Humanos , Recién NacidoRESUMEN
Not required for Clinical Vignette.
Asunto(s)
Glándula Tiroides/diagnóstico por imagen , Glándula Tiroides/cirugía , Nódulo Tiroideo/diagnóstico por imagen , Nódulo Tiroideo/cirugía , Adolescente , Femenino , Humanos , Hipertiroidismo/etiología , Glándula Tiroides/patología , Nódulo Tiroideo/patología , Tirotropina/sangre , Tiroxina/sangreRESUMEN
Not required for Clinical Vignette.