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1.
Anesth Analg ; 137(1): 191-199, 2023 07 01.
Article En | MEDLINE | ID: mdl-37115721

BACKGROUND: Anesthesia-related causes contribute to a significant proportion of perioperative deaths, especially in low and middle-income countries (LMICs). There is evidence that complications related to failed airway management are a significant contributor to perioperative morbidity and mortality. While existing data have highlighted the magnitude of airway management complications in LMICs, there are inadequate data to understand their root causes. This study aimed to pilot an airway management capacity tool that evaluates airway management resources, provider practices, and experiences with difficult airways in an attempt to better understand potential contributing factors to airway management challenges. METHODS: We developed a novel airway management capacity assessment tool through a nonsystematic review of existing literature on anesthesia and airway management in LMICs, internationally recognized difficult airway algorithms, minimum standards for equipment, the safe practice of anesthesia, and the essential medicines and health supplies list of Uganda. We distributed the survey tool during conferences and workshops, to anesthesia care providers from across the spectrum of surgical care facilities in Uganda. The data were analyzed using descriptive methods. RESULTS: Between May 2017 and May 2018, 89 of 93 surveys were returned (17% of anesthesia providers in the country) from all levels of health facilities that provide surgical services in Uganda. Equipment for routine airway management was available to all anesthesia providers surveyed, but with a limited range of sizes. Pediatric airway equipment was always available 54% of the time. There was limited availability of capnography (15%), video laryngoscopes (4%), cricothyroidotomy kits (6%), and fiber-optic bronchoscopes (7%). Twenty-one percent (18/87) of respondents reported experiencing a "can't intubate, can't ventilate" (CICV) scenario in the 12 months preceding the survey, while 63% (54/86) reported experiencing at least 1 CICV during their career. Eighty-five percent (74/87) of respondents reported witnessing a severe airway management complication during their career, with 21% (19/89) witnessing a death as a result of a CICV scenario. CONCLUSIONS: We have developed and implemented an airway management capacity tool that describes airway management practices in Uganda. Using this tool, we have identified significant gaps in access to airway management resources. Gaps identified by the survey, along with advocacy by the Association of Anesthesiologists of Uganda, in partnership with the Ugandan Ministry of Health, have led to some progress in closing these gaps. Expanding the availability of airway management resources further, providing more airway management training, and identifying opportunities to support skilled workforce expansion have the potential to improve perioperative safety in Uganda.


Anesthesiology , Anesthetics , Humans , Child , Uganda , Cross-Sectional Studies , Airway Management/adverse effects
2.
Eplasty ; 15: e6, 2015.
Article En | MEDLINE | ID: mdl-25848443

INTRODUCTION: First described by Von Recklinghausen in 1891, fibrous dysplasia is a developmental defect of osseous tissue such that bone is produced with an abnormally thin cortex and marrow is replaced with fibrous tissue that demonstrates characteristic ground-glass appearance on x-ray examination. The underlying defect in fibrous dysplasia is a mutation of the GNAS1 gene, which leads to constitutive activation of gene products that preclude the maturation of osteoprogenitor cells and lead to development of abnormal bone matrix, trabeculae, and collagen, produced by undifferentiated mesenchymal cells. There exists a mainly self-limiting form of fibrous dysplasia classified as monostotic, which is characterized by dysplastic bone in a single location that remains relatively stable throughout life and a polyostotic form, which can exhibit aggressive growth placing adjacent structures at risk for compressive sequelae. METHODS: We present the surgical management of an unusual case of monostotic fibrous dysplasia, which exhibited aggressive growth with mass effect, and late presentation, both uncharacteristic features for the monostotic form. The authors also performed a comprehensive review of the literature and discuss the disease process, management options, and indications for surgical treatment. RESULTS: An overview of the disease process and management options is presented. The authors also present details of reconstruction in an unusual form of symptomatic monostotic fibrous dysplasia. CONCLUSION: Conservative management is usually the mainstay of therapy in asymptomatic cases of fibrous dysplasia. In patients fulfilling criteria for surgical management, craniofacial reconstruction offers a viable option in the surgeon's armamentarium, providing good functional and cosmetic outcomes.

3.
Nurs Stand ; 28(24): 46-50, 2014.
Article En | MEDLINE | ID: mdl-24517695

Genital warts are a common sexually transmitted infection that is particularly prevalent in young people. Although the warts are usually painless and rarely cause any long-term health problems, they can cause significant psychological distress and relationship problems for those affected. This article provides an overview of genital warts to enable nurses to guide people in the prevention and treatment of the infection.


Condylomata Acuminata/physiopathology , Condylomata Acuminata/diagnosis , Condylomata Acuminata/therapy , Diagnosis, Differential , Female , Humans , Male , Referral and Consultation
6.
Nurs Stand ; 20(8): 26-7, 2005.
Article En | MEDLINE | ID: mdl-16295596

Flu is at best miserable and at worst can have serious complications. Children are as vulnerable to the infection as adults and in certain circumstances vaccination is recommended. Attack rates of the virus are highest in preschool and school age children. Symptoms in children are the same as in adults but may also be accompanied by nausea, vomiting and diarrhoea. Children are at higher risk of complications, especially otitis media. In England and Wales in 2003, 11 children aged between one and four died from flu.


Influenza, Human/transmission , Child , Child Care , Child, Preschool , Disease Transmission, Infectious , Dose-Response Relationship, Immunologic , Humans , Infant , Influenza Vaccines/administration & dosage , Influenza, Human/epidemiology , Influenza, Human/prevention & control , Prevalence , United Kingdom/epidemiology
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