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Appl Biochem Biotechnol ; 182(1): 181-196, 2017 May.
Artículo en Inglés | MEDLINE | ID: mdl-27830465

RESUMEN

Plant proteases are capable of performing several functions in biological systems, and their use is attractive for biotechnological process due to their interesting catalytic properties. Bromelia pinguin (aguama) is a wild abundant natural resource in several regions of Central America and the Caribbean Islands but is underutilized. Their fruits are rich in proteases with properties that are still unknown, but they represent an attractive source of enzymes for biotechnological applications. Thus, the proteolytic activity in enzymatic crude extracts (CEs) from wild B. pinguin fruits was partially characterized. Enzymes in CEs showed high proteolytic activity at acid (pH 2.0-4.0) and neutral alkaline (pH 7.0-9.0) conditions, indicating that different types of active proteases are present. Proteolytic activity inhibition by the use of specific protease inhibitors indicated that aspartic, cysteine, and serine proteases are the main types of proteases present in CEs. Activity at pH 3.0 was stable in a broad range of temperatures (25-50 °C) and retained its activity in the presence of surfactants (SDS, Tween-80), reducing agents (DTT, 2-mercapoethanol), and organic solvents (methanol, ethanol, acetone, 2-propanol), which suggests that B. pinguin proteases are potential candidates for their application in brewing, detergent, and pharmaceutical industries.


Asunto(s)
Proteasas de Ácido Aspártico/química , Bromelia/enzimología , Proteasas de Cisteína/química , Frutas/enzimología , Proteínas de Plantas/química , Serina Proteasas/química , Proteasas de Ácido Aspártico/antagonistas & inhibidores , Proteasas de Ácido Aspártico/aislamiento & purificación , Bromelia/química , Proteasas de Cisteína/aislamiento & purificación , Ditiotreitol/química , Pruebas de Enzimas , Frutas/química , Concentración de Iones de Hidrógeno , Cinética , Mercaptoetanol/química , Extractos Vegetales/química , Proteínas de Plantas/antagonistas & inhibidores , Proteínas de Plantas/aislamiento & purificación , Polisorbatos/química , Inhibidores de Proteasas/química , Proteolisis , Serina Proteasas/aislamiento & purificación , Dodecil Sulfato de Sodio/química , Solventes/química
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