Affordance-based control of braking in cycling: Experience reveals differences in the style of control.

We investigated whether in an in-situ collision avoidance experiment cyclists regulate braking by adopting an affordance-based control strategy. Within an affordance-based control strategy for braking, deceleration is controlled relative to the maximum achievable deceleration rather than by nulling out deviations from ideal deceleration, and potentially allowing for different braking styles. Twenty active- and eighteen inactive-cyclists were asked to cycle on a straight path in an indoor gym and to stop as close as possible in front of a stationary obstacle. Maximum achievable deceleration was manipulated by loading the bike: no-load, load-5 kg, and load-10 kg. Two approach distances were used to vary cycling speed. Participants in both groups stopped farther from the obstacle when approaching with long- than short-initial distance conditions. No systematic effects of loading on braking performance and control were found across the two groups. However, both groups did increase the magnitude of brake adjustments as ideal deceleration increased and got closer to the action boundary, even when current deceleration approached the ideal deceleration. This indicates that participants adopted an affordance-based control strategy for braking. Two braking styles were identified: an aggressive style, characterized by a late braking onset and a high, steep peak in ideal deceleration, and a conservative style, characterized by an early braking onset and gradual, linear increase in ideal deceleration. The aggressive braking style was more prevalent among the active-cyclists. We suggest that the braking styles emerge from differences in calibration between information and action. The novelty of our work lies in confirming that cyclists adopt an affordance-based control strategy in an in-situ experiment and in demonstrating and explicating how affordance-based control can incorporate the emergence of different styles of braking.

Diabetic older women without peripheral neuropathy amplify body sway but are capable of improving postural stability during a saccadic gaze task.

BACKGROUND: Diabetic older people tend to present deteriorated performance in balance and locomotion activities, even those without peripheral neuropathy. There is evidence that saccadic eye movements are used to reduce body sway in young and older healthy adults, but it has not been shown that diabetic older people preserve this visuomotor adaptation capacity. RESEARCH QUESTION: Are diabetic older women without peripheral neuropathy capable of improving postural stability during a saccadic gaze task? METHODS: Seventeen type 2 diabetic older women (68.2 ± 10.7 years old) and seventeen healthy women, age-matched controls (66.0 ± 8.4 years old) voluntarily participated in the study. All participants were instructed to stand upright, barefoot, as stable as possible, for 30 s. Participants maintained their feet parallel to each other, at standard and narrow bases of support, while either fixating on a stationary target (fixation condition) or performing horizontal saccadic eye movements to follow a target (eccentricity of 11° of visual angle), which continuously disappeared and reappeared immediately on the opposite side (saccade 0.5 Hz and saccade 1.1 Hz conditions). RESULTS: Results indicated that the diabetic group clearly had deteriorated postural control, as shown by increased values of mean sway amplitude and mean sway velocity. However, diabetic and control groups were similarly capable of using saccadic eye movements to improve their postural stability, reducing their sway velocity compared to a gaze fixation condition. SIGNIFICANCE: Diabetes per se (without peripheral neuropathy) amplifies postural sway of older women as compared to their healthy age-matched controls. However, diabetic older women without peripheral neuropathy are capable of improving postural stability during a saccadic gaze task.

Biological aspects and first record of Leucothyreus alvarengai Frey (Coleoptera: Melolonthidae: Rutelinae) in sugarcane (Saccharum officinarum L) (Poaceae) fields of Mato Grosso do Sul state, Brazil.

Larvae of Leucothyreus spp. have been reported causing damage to several crops in Brazil. From May 2012 to April 2013, adults and immatures of Leucothyreus alvarengai Frey (Coleoptera: Melolonthidae: Rutelinae) samples were obtained from sugarcane (Saccharum officinarum L.) (Poaceae) fields in the municipalities of Naviraí and Nova Andradina, Mato Grosso do Sul, Brazil. Adults were collected with the aid of light traps, whereas immatures were sampled by opening two trench sizes (30 x 30 x 30 cm and 80 x 50 x 40 cm) in the soil, beside the plants. The collected larvae were reared in laboratory conditions, fed by sugarcane seedlings. The biological cycle of L. alvarengai was completed in 230 days, displaying three larval instars with mean size of the cephalic capsule of 1.68, 2.46, and 3.00 mm for the first, second, and third instar, respectively. Adults were collected in greater numbers in December 2012, and first-instar larvae were observed as of January 2013. Conversely, pupae were observed in the field from July 2012 to January 2013. This is the first record of larvae and adults of L. alvarengai in sugarcane fields in Mato Grosso do Sul state, contributing with the knowledge about its biology and temporal distribution in the field.

Effect of dry needling and instrumental myofascial release on masticatory, facial, and cervical muscles of patients with temporomandibular disorders of muscular origin.

Background: To evaluate the effectiveness of dry needling (DN) and instrumental myofascial release (IMR) therapies in the cervico-cranio-mandibular system through pain, bite force, and distribution of occlusal contacts in patients with muscular temporomandibular disorders. Material and Methods: Thirty patients were divided into treatment groups: DN (n=15) and IMR (n=15). Therapeutic efficacy regarding pain perception and tolerance of masticatory, facial, and cervical muscles, bite force, and distribution of occlusal contacts were analyzed in this observational longitudinal clinical study pre/post-intervention and pre/post one month of therapeutic intervention. The data were tabulated and statistically analyzed (repeated measures and Bonferroni post-hoc test, p<0.05). Results: There was a statistically significant difference in pain between the groups in the comparison of pre- and post-intervention with effect on time versus intervention in the head and neck. Pain perception and tolerance showed a statistical effect of time on the temporal, suboccipital, sternocleidomastoid, mental (right and left), right masseter, and left trapezius muscles. There was a statistically significant effect of the intervention on the mentalis, supraorbital, and infraorbital (right and left) muscles. There was a statistically significant effect of the interaction on the upper masseter (right and left), anterior temporal (left), suboccipital, sternocleidomastoid, and mentalis (left) muscles. There was an increase in post-intervention molar bite force in the groups, with a statistical effect on time versus intervention in the right and left regions. Contact of occlusal forces at the maxilla/mandible interface showed a difference between the mean times on teeth 26-36 after versus 1 month after the intervention. Conclusions: The two therapeutic techniques are viable for the treatment of muscular temporomandibular disorders; however, IMR proved to be more effective immediately after the intervention and after one month. Key words:Temporomandibular disorders, pain, masticatory muscles, facial muscles, cervical muscles, dry needling, instrumental myofascial release.

COSMO models for the pharmaceutical development of parenteral drug formulations.

The aqueous solubility of active pharmaceutical ingredients is one of the most important features to be considered during the development of parenteral formulations in the pharmaceutical industry. Computational modelling has become in the last years an integral part of pharmaceutical development. In this context, ab initio computational models, such as COnductor-like Screening MOdel (COSMO), have been proposed as promising tools for the prediction of results without the effective use of resources. Nevertheless, despite the clear evaluation of computational resources, some authors had not achieved satisfying results and new calculations and algorithms have been proposed over the years to improve the outcomes. In the development and production of aqueous parenteral formulations, the solubility of Active Pharmaceutical Ingredients (APIs) in an aqueous and biocompatible vehicle is a decisive step. This work aims to study the hypothesis that COSMO models could be useful in the development of new parenteral formulations, mainly aqueous ones.

Vocal Folds Leukoplakia: The Efficacy of Vitamin A in the Initial Treatment

Abstract Introduction Laryngeal leukoplakia corresponds to a white lesion in the mucosa developed by the deposit of keratin in the epithelium, potentiated by chronic smoking. It is considered a preneoplastic lesion. Surgery is the most adopted treatment; however, non-surgical treatment is advocated by some authors. Objective To evaluate the effectiveness of vitamin A in the management of vocal fold leukoplakia. Methods Patients with videolaryngoscopy diagnosis of vocal fold leukoplakia were selected. The endoscopic images were photographed and with the aid of the ImageJ software (National Institutes of Health, Bethesda, MD, USA), the proportion of the size of the leukoplakia was calculated. Eligible patients were prescribed 50,000U of vitamin A, twice daily for 2 months, at which point videolaryngostroboscopy was repeated for comparative analysis between pre and posttreatment. The efficacy of the treatment was classified as: outcome I - complete improvement of the lesion, outcome II - partial improvement, and outcome III - no difference or increased lesion size. Results Fifteen patients (eight women, seven men) were included, six of whom had bilateral lesions. Smoking was reported in 86.8% of patients. Complete improvement of the lesion was found in 7 cases (33.4%, outcome I), partial improvement in 6 (28.6%, outcome II), and worsening of the injury in 8 (38.1%, outcome III). Of the latter, 6 underwent microsurgery; histopathology indicated absence of dysplasia in 3, and mild dysplasia in 3. Conclusions In this study, the treatment with vitamin A at a dose of 100,000 IU daily for 2 months was effective in reducing the laryngeal leukoplakia size in 62% of cases.

Vocal Folds Leukoplakia: The Efficacy of Vitamin A in the Initial Treatment.

Introduction Laryngeal leukoplakia corresponds to a white lesion in the mucosa developed by the deposit of keratin in the epithelium, potentiated by chronic smoking. It is considered a preneoplastic lesion. Surgery is the most adopted treatment; however, non-surgical treatment is advocated by some authors. Objective To evaluate the effectiveness of vitamin A in the management of vocal fold leukoplakia. Methods Patients with videolaryngoscopy diagnosis of vocal fold leukoplakia were selected. The endoscopic images were photographed and with the aid of the ImageJ software (National Institutes of Health, Bethesda, MD, USA), the proportion of the size of the leukoplakia was calculated. Eligible patients were prescribed 50,000U of vitamin A, twice daily for 2 months, at which point videolaryngostroboscopy was repeated for comparative analysis between pre and posttreatment. The efficacy of the treatment was classified as: outcome I - complete improvement of the lesion, outcome II - partial improvement, and outcome III - no difference or increased lesion size. Results Fifteen patients (eight women, seven men) were included, six of whom had bilateral lesions. Smoking was reported in 86.8% of patients. Complete improvement of the lesion was found in 7 cases (33.4%, outcome I), partial improvement in 6 (28.6%, outcome II), and worsening of the injury in 8 (38.1%, outcome III). Of the latter, 6 underwent microsurgery; histopathology indicated absence of dysplasia in 3, and mild dysplasia in 3. Conclusions In this study, the treatment with vitamin A at a dose of 100,000 IU daily for 2 months was effective in reducing the laryngeal leukoplakia size in 62% of cases.

Methyl benzoate and nerolidol attract the cyclocephaline beetle Cyclocephala paraguayensis to trumpet flowers.

Cyclocephaline beetles are flower visitors attracted primarily by major floral volatiles. Addressing the identity of these volatile compounds is pivotal for understanding the evolution of plant-beetle interactions. We report the identification and field testing of the attractant volatiles from trumpet flowers, Brugmansia suaveolens (Willd.) Sweet (Solanaceae), for the beetle Cyclocephala paraguayensis Arrow (Melolonthidae: Dynastinae). Analysis of headspace floral volatiles revealed 19 compounds, from which eucalyptol (57%), methyl benzoate (16%), and ß-myrcene (6%) were present in the largest amounts, whereas E-nerolidol in much lesser amounts (1.8%). During a first-field assay, traps baited with Mebe alone or blended with the other two major compounds attracted more beetles than myrcene and eucalyptol alone, which did not differ from the negative controls. In a second assay, Mebe and nerolidol attracted more beetles as a blend than individually. Nerolidol was more attractive than Mebe, and all treatments attracted more beetles than negative controls. The number of attracted beetles in the Mebe-nerolidol blend was greater than the combined sum of beetles attracted to these compounds alone, suggesting a synergistic interaction. The attraction of C. paraguayensis by trumpet-flower volatiles supports the beetle's extended preference for sphingophilous plants, especially when cantharophilous (beetle-pollinated) flowers are lacking. This phenomenon, thus, might have contributed to the widespread occurrence of this beetle throughout the Brazilian biomes.

Does Abrupt Weight Loss Caused by Bariatric Surgery Compromise the Voice in Women?

OBJECTIVE: To evaluate vocal symptoms, voice characteristics and videolaryngoscopy in obese women before and after bariatric surgery. METHODS: Obese patients (18 to 59 years old), candidates for bariatric surgery were recruited. Evaluation times: T1 (preoperative), T2 (after six months), T3 (after 12 months). Evaluated parameters: weight, height, body mass index, abdominal and neck circumference, vocal self-assessment, perceptual and acoustic vocal assessment, and videolaryngoscopy. RESULTS: A total of 37 obese women were included, average age 40.8 years. There was a decrease in anthropometric measurements between the preoperative assessment and after 12 months: weight (121.18 ± 15.4 kg; 77.1 ± 11.6 kg), BMI (46.6 ± 6.95 kg/m2; 30 ± kg/m2), abdominal circumference (128 ± 16.1; 99.1 ± 12.1), and neck circumference (41.1 ± 5.85; 36.6 ± 3.02). Gastroesophageal (21.6%) and vocal symptoms (27%) prevailed. No difference was identified in vocal self-assessment between the evaluations. In the acoustic analysis, f0 increased and the soft phonation index decreased. The perceptual analysis registered lower scores for the degree of dysphonia (G) and voice instability (I). The maximum phonation time values increased without changing the s/z ratio. Videolaryngoscopies showed a posterior middle cleft and improvement in the signs of reflux. CONCLUSIONS: Bariatric surgery led to an important and gradual decrease in anthropometric parameters. The voice became less hoarse, with higher pitch and more stable, with an improvement in maximum phonation time, however with slight breathiness. Such changes were not noticed by the patients.

Antennal sensilla of two species of Gymnetis MacLeay, 1819 (Coleoptera: Scarabaeidae: Cetoniinae)

ABSTRACT The present study describes the morphology of the antennal sensilla of adults of Gymnetis holosericea (Voet, 1779) and Gymnetis rufilateris (Illiger, 1800). The adults of Gymnetis spp. were sexed and antenna of males and females were dissected. Both species have sensilla chaetica, trichodea, placodea (type I and II), coeloconica (type I and II), and ampullacea (or pore). Females of G. holosericea have a total of about 19,995 sensilla and males have about 23,273 sensilla, and females of G. rufilateris have about 16,633 sensilla and males have about 21,184 sensilla. Sensilla placodea are the predominant type of sensilla in males and females of G. holosericea and G. rufilateris.

Concentration of Fibroblasts in the Vocal Fold of Elderly.

OBJECTIVE: To study the concentration of fibroblasts in the vocal folds of elderly people. MATERIAL AND METHODS: The vocal folds of 13 cadavers were removed and divided into two age groups: Control group: n-5, 18-40 years; Elderly group: n-8, ≥75 years). The vocal folds were dissected and prepared for immunohistochemical analysis using the SA100 antibody to fibroblasts. The sites analyzed were maculae flavae and medial (or vibrating) portion of the vocal folds. The AVsoft program was used to count the cells. RESULTS: A higher concentration of fibroblasts was identified in the maculae flavae of the larynx of young adults and in the medial portion of the vocal folds of the elderly. However, these results did not determine statistically significant differences, allowing us to conclude that there was no effect of age on the concentration of fibroblasts in the vocal folds. CONCLUSION: In the larynx of the elderly, the fibroblast population remains similar to the young adults, both in the maculae flavae and in the body of the vocal folds, possibly being responsible for the constant production of fibrous matrix in the lamina propria. Functional changes in these cells are probably more marked than quantitative ones.

Protocol for reducing radiation exposure during pediatric thoracic radiography.

INTRODUCTION: This work aims to assess if the anode position during chest radiography of pediatric patients with heart congenital disease (HCD) influences medical image results. The approach is to reverse the orientation of the x-ray tube, with the anode end directed towards the patient's face (anode-heel effect). METHODS: Five specialists analyzed 48 images, 24 from the control group (CG) and 24 with the anode end directed towards the patients' face (experimental group, EC). An ionization chamber was used to assess radiation dose received by sensitive organs. RESULTS: The specialists considered both CG and EC images acceptable. But, the EC group's dose evaluation revealed that the thyroid received 12% less radiation and the gonads presented a 5.9% reduction. Based on the results, a new protocol was developed. DISCUSSION/CONCLUSION: The standardization of radiographic imaging procedures will reduce acquisition errors, resulting in adequate images in pediatric patients with HCD with less radiation dose, thus increasing patient safety and extending the life of the equipment.

Effect of Aging on the Vocal Muscle.

INTRODUCTION: Sarcopenia is a common and natural condition in the elderly, and leads to loss of muscle mass and function. In the presbylarynx there is atrophy of the vocal folds, however the degree of vocal muscle atrophy is poorly studied and the results are contradictory. AIMS: The aim of this study was to evaluate the effect of aging on the vocal muscle (thyroarytenoid muscle). METHODS: Thirteen larynxes removed during necropsy from 13 cadavers were included into two age groups: Control group - G1 (n5), between 25 and 40 years; Elderly Group - GI (n-8), aged 70 years or older. The vocal folds were dissected and prepared for scanning electron microscopy, ensuring a cross-section in the musculature area to allow measurements of muscle fiber parameters. Images were analyzed and photographed at different magnifications. Through the ImageJ software, ten distinct fields of each part were selected. Parameters studied:  area, perimeters and diagonals of the thyroarytenoid muscle bundles of both groups. RESULTS: The cross-sectional areas, perimeters and diagonals of the muscle fibers of the thyroarytenoid muscle of the elderly group were significantly smaller than those of the control group. CONCLUSION: We demonstrated that the vocal muscle is affected in the presbylarynx, with a reduction of its muscle fibers, corresponding to muscle atrophy. However, these findings may not be directly related to vocal symptoms because the patient may develop muscle compensatory mechanisms capable of reducing glottic insufficiency.

Antennal sensilla in Cyclocephala literata Burmeister, 1847 (Coleoptera: Scarabaeidae: Dynastinae) / Sensilas antenais em Cyclocephala literata Burmeister, 1847 (Coleoptera: Scarabaeidae: Dynastinae)

Abstract: Adults of the beetle Cyclocephala literata Burmeister, 1847 are important pollinators to some Magnoliaceae. Is known that insects could find host plants by detecting volatiles through antennal sensilla. Cyclocephala has its three distal antennomeres lamellate, and the surface of each lamella has sensilla trichodea, chaetica, placodea, coeloconica, basiconica and ampullacea. Three kinds of sensilla placodea were found (type I, II and III), and two kinds of sensilla coeloconica were observed (type I and II). Females have on average 10,776 sensilla, of which 10,214 are sensilla placodea, 536 are sensilla coeloconica, and 26 are sensilla basiconica. Males have on average 10,386 sensilla, of which 9,873 are sensilla placodea, 464 are sensilla coeloconica, and 49 are sensilla basiconica. Males and females have similar quantities of sensilla, and sensilla placodea are predominant. The differences observed in the number of sensilla of males and females were found in other beetles and were attributed to the detection of cospecific sexual pheromones by one of the sexes, or to the detection of plant volatiles. The antennal sensilla of C. literata is described and quantified in present study, and some perspectives about the differences kind of chemical communication, pollination, and antennae dimorphism is discussed.

Resumo: Adultos do besouro Cyclocephala literata Burmeister, 1847 desempenham importantes funções de polinização em plantas da família Magnoliaceae. É conhecido que muitos insetos encontram plantas hospedeiras pela detecção de voláteis pelas sensilas antenais. Cyclocephala possui os três antenômeros distais lamelados e na superfície de cada lamela possuem sensila trichodea, caética, placódea, coelocônica, basicônica e ampulacea. Foram encontrados três tipos de sensilas placódeas (tipo I, II e III), e dois tipos de sensilas coelocônicas (tipo I e II). Fêmeas apresentam em média 10.776 sensilas, das quais 10.214 são sensilas placódeas, 536 são sensilas coelocônicas e 26 são sensilas basicônicas. Os machos apresentaram em média 10.386 sensilas, das quais 9.873 são sensilas placódeas, 464 são sensilas coelocônicas e 49 são sensilas basicônicas. Machos e fêmeas apresentam quantidades semelhantes de sensilas e as sensilas placódeas são predominantes. As diferenças encontradas nas quantidades de sensilas em machos e fêmeas também foram encontradas em outros besouros e foram atribuídas a detecção de feromônios coespecíficos por um dos sexos, ou para detecção de voláteis de plantas. A sensila antenal de C. literata é descrita e quantificada no presente estudo, e algumas perspectivas sobre as diferenças entre os tipos de comunicação química, polinização e dimorfismo antenal é discutido.

Parkinson's disease affects gaze behaviour and performance of drivers.

The aim of this study was to investigate the effects of PD and ageing on gaze behaviour and performance of drivers in a simulated task. Ten drivers with PD, ten neurologically healthy older drivers, and ten neurologically healthy younger adult drivers were asked to drive in a car simulator for three minutes, maintaining car speed between 100 and 120 km/h and avoiding collisions. Driver's eye movements were recorded. Drivers with PD had more collisions and spent less time driving within the speed zone than the younger-drivers. Drivers with PD performed an increased number of fixations towards task-irrelevant areas of the visual scene and higher visual entropy, indicating a more random gaze behaviour. Older drivers restricted their visual search to the lane area in order to detect threat-related stimuli. PD led to drops in performance of drivers in the car simulator. Practitioner summary: Parkinson's disease (PD) and ageing process caused a drop in driving performance. Drivers with PD made fewer fixations on task-relevant information and showed higher visual entropy than young adults. Older drivers restricted their visual search to the lane than other areas of interest.

Saccadic eye movement performance reduces visual manipulation influence and center of pressure displacements in older fallers.

This study examined changes in postural control and gaze performance of faller and non-faller older adults under conditions of visual tasks and optical flow manipulations. Fifteen older non-fallers (69.8 years, ± 3.2) and fifteen older fallers (71.1 years, ± 6.4) stood on a force platform inside a moving room wearing an eye tracker. Four tasks were performed: gaze fixation; predictable saccades; unpredictable saccades; and free-viewing. The stimuli appeared at a frequency of 1.1 Hz during conditions of predictable and unpredictable saccades. Sixteen trials were divided into two blocks. In the first block, the room remained stationary. In the second block, the room oscillated, without the participant's awareness, with a 0.6 cm amplitude and 0.2 Hz frequency. Results showed postural sway attenuation in older fallers during the saccadic tasks compared to gaze fixation and free-viewing tasks, in both stationary and moving room conditions. Both groups showed increased center of pressure (CoP) magnitude during the moving room condition and CoP displacements strongly coupled to the room's movement. The influence of the moving room on the postural sway was reduced during the saccadic tasks for both older groups. Older fallers exhibited higher variability compared to older non-fallers. Gaze behavior differences between groups were dependent on the goals of the visual tasks. Therefore, CoP displacements of older adults are reduced during saccadic tasks regardless of their falling history. However, postural and gaze performance of older fallers suggests increased deterioration of postural and oculomotor control which may be used as a predictor of fall risk.

Variability of visually-induced center of pressure displacements is reduced while young adults perform unpredictable saccadic eye movements inside a moving room.

This study investigated the modulation of center of pressure (CoP) displacements of young adults as they performed predictable and unpredictable saccadic eye movements in stationary and moving visual scenarios. We also examined whether the relationship between CoP displacements and visual stimulus, provided by the moving scenario, and gaze control itself, are affected by the demands of the saccadic tasks. Fifteen young adults (20.53 ± 2.1 years old) stood upright on a force plate, inside a moving room, wearing an eye tracker while performing three tasks: gaze fixation (fixating on a target in the center of the screen), predictable task (saccades while following a target which continuously appeared and disappeared on the right and left sides), and unpredictable task (similar to the previous task, but the participants did not know which side the target would appear on). For saccadic tasks, the target appeared at a frequency of 1.1 Hz and with eccentricity of 11.5 degrees of visual angle. Two blocks of six trials were performed: in the first block, the room remained stationary and in the second, it oscillated (0.6 cm amplitude; 0.2 Hz frequency). Mean amplitude of CoP displacements was lower in the saccadic tasks compared to the gaze fixation, in both conditions; and higher in the moving scenario than in the stationary condition. Variability of CoP displacements was lower in the unpredictable saccades than gaze fixation task. Saccade reaction time was longer in the unpredictable than predictable task. We conclude that CoP displacements are reduced to facilitate performance of the saccadic tasks regardless of conditions and task complexity. Furthermore, lower variability suggests modulation of CoP displacements to deal with the increased attentional demands associated with the performance of the unpredictable saccades, indicating the important role of visual task constraints in postural control.

Is there a relationship between diet quality and bone health in elderly women? A cross-sectional study.

OBJECTIVE: To evaluate whether there is a relationship between diet quality and bone health in a group of elderly Brazilian women. METHODS: A cross-sectional study was performed with 105 elderly women. Participants were evaluated regarding diet quality (good, needing improvement, and poor) and its relationship with bone mineral density (BMD), bone-specific alkaline phosphatase (BSAP), and C-telopeptide (CTX). RESULTS: Fifty eight participants (55.2%) presented a poor-quality diet and 47 (44.8%) required dietary improvements, while no subjects presented a good quality diet. The group requiring dietary improvements had lower CTX [0.35 (0.05;1.09) vs. 0.52 (0.10;1.45); p = 0.03)] and BSAP (38.7 ± 12.9 U/L vs. 46.10 ± 15.2 U/L; p < 0.01) levels than the poor-quality diet group. Groups did not differ in terms of BMD. CONCLUSION: In this group of elderly Brazilian women, there was a relationship between diet quality and bone health, where worse diet quality was associated with higher levels of bone remodelling markers.

Development of an Index for the Inspection of Aedes aegypti Breeding Sites in Brazil: Multi-criteria Analysis.

BACKGROUND: Aedes aegypti is a vector for the transmission of diseases such as dengue fever, chikungunya, Zika fever, and yellow fever. In 2016, over 1 million cases of these diseases were reported in Brazil, which is an alarming public health issue. One of the ways of controlling this disease is by inspecting and neutralizing the places where A. aegypti lays its eggs. The Ministry of Planning, Development, and Administration of Brazil maintains the inspection statistics. OBJECTIVE: We propose a multi-criteria analysis to create an index for A. aegypti inspections reported through the Ministry of Planning, Development, and Administration system of Brazil. METHODS: Based on the repository from urban cleaning services combined with data on inspections conducted by government agencies in several Brazilian cities and municipalities, we selected and combined metrics, which we further ranked using the analytic hierarchy process methodology. We also developed risk maps based on the analytic hierarchy process ranking of the A. aegypti breeding sites. RESULTS: Based on our analysis and the available data, the priority for inspections should consider the number of sick people (weight 0.350), medical evaluations (weight 0.239), inspections (weight 0.201), mosquito breeding sites (weight 0.126), and days of absence from work (weight 0.096). CONCLUSIONS: The proposed index could aid public health practitioners in preventing the appearance of new A. aegypti breeding sites. This information technology application can help solve such public health challenges.

Motor strategy during postural control is not muscle fatigue joint-dependent, but muscle fatigue increases postural asymmetry.

The aim of this study was to investigate the effects of ankle and hip muscle fatigue on motor adjustments (experiment 1) and symmetry (experiment 2) of postural control during a quiet standing task. Twenty-three young adults performed a bipedal postural task on separate force platforms, before and after a bilateral ankle and hip muscle fatigue protocol (randomized). Ankle and hip muscles were fatigued separately using a standing calf raise protocol (ankle fatigue) on a step and flexion and extension of the hip (hip fatigue) sitting on a chair, at a controlled movement frequency (0.5Hz), respectively. In both experiments, force, center of pressure, and electromyography parameters were measured. The symmetry index was used in experiment 2 to analyze the postural asymmetry in the parameters. Our main findings showed that muscle fatigue impaired postural stability, regardless of the fatigued muscle region (i.e., ankle or hip). In addition, young adults used an ankle motor strategy (experiment 1) before and after both the ankle and hip muscle fatigue protocols. Moreover, we found increased asymmetry between the lower limbs (experiment 2) during the quiet standing task after muscle fatigue. Thus, we can conclude that the postural motor strategy is not muscle fatigue joint-dependent and a fatigue task increases postural asymmetry, regardless of the fatigued region (hip or ankle). These findings could be applied in sports training and rehabilitation programs with the objective of reducing the fatigue effects on asymmetry and improving balance.