Recalling prior experiences with a close other can fulfill the need for social connection.

Humans need social connection to thrive, but how we fulfill this need is not well understood. Numerous theoretical perspectives propose that continual positive experiences with a close other fulfill the need for social connection. Despite popular acceptance for this notion, little research has investigated the consequences of having multiple experiences with a close other. As a first step toward this goal, the current studies assessed whether recalling prior experiences of social connection with a close other alters feelings of satisfaction toward the same person, the implications of such feelings for social desires outside of the lab (Study 1), and possible brain mechanisms related to fulfilling the need for social connection (Study 2). Consistent with hypotheses, recalling experiences increased feelings of satisfaction toward the close other, but not toward an acquaintance. Further, recalling prior experiences uniquely increased the desire for additional social interaction with the close other, compared with others in general. In Study 2, brain regions related to satiety-the ventral striatum (VS) and ventromedial prefrontal cortex (VMPFC)-showed different patterns to recalling prior experiences with a single close other such that VS activity decreased over recalled experiences, while VMPFC activity remained stable. VMPFC activity, but not VS activity, to recalling experiences with a close other was associated with greater feelings of satisfaction. Together, results are consistent with the proposal that positive experiences, particularly with close others, satisfy the need for social connection. Implications for preventing feelings of social disconnection and maintaining social relatonships over time are discussed. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Relationships Between Early Maternal Warmth and Social Connection: A Randomized Clinical Trial With Naltrexone.

OBJECTIVE: Early experiences of having received maternal warmth predict responses to opportunities to connect with others later in life. However, the understanding of neurochemical mechanisms by which such relationships emerge remains incomplete. Endogenous opioids, involved in social connection in both animals and humans, may contribute to this link. Therefore, the current study examined a) relationships between early maternal warmth and brain and self-report responses to novel social targets (i.e., outcomes that may promote social connection) and b) the effect of the opioid antagonist, naltrexone, on such relationships. METHODS: Eighty-two adult participants completed a retrospective report of early maternal warmth. On a second visit, participants were randomized to 50 mg of oral naltrexone (n = 42) or placebo (n = 40), followed by a magnetic resonance imaging scan where functional brain activity in response to images of novel social targets (strangers) was assessed. Approximately 24 hours later, participants reported on their feelings of social connection since leaving the scanner. RESULTS: In the placebo condition, greater early maternal warmth was associated with less dorsal anterior cingulate cortex, anterior insula, ventral striatum, and amygdala activity in response to images of novel social targets (r values ≥ -0.360, p values ≤ .031), and greater feelings of social connection (r = 0.524, p < .001) outside of the laboratory. The same relationships, however, were not present in the naltrexone condition. CONCLUSIONS: Results highlight relationships between early maternal warmth and responses to the social world at large and suggest that opioids might contribute to social connection by supporting the buffering effects of warm early life experiences on social connection later in life.Trial Registration: Clinical Trials NCT02818036.

A body-to-mind perspective on social connection: Physical warmth potentiates brain activity to close others and subsequent feelings of social connection.

Social connection may stem from afferent pathways that bring bodily information to the brain and mind. In support of this perspective, research from animals and humans shows that physical warmth causally affects experiences of social connection. However, whether physical warmth affects feelings of social connection and the brain's response to close others remains unknown. In the current study, 42 participants completed an fMRI scan as they viewed images of a close other and strangers while holding warm, cold, and room-temperature objects. Following the scan, participants reported on their feelings of social connection and pleasure in response to the three temperature conditions. Results revealed a specific effect of physical warmth on brain activity to close others as compared with cooler temperatures (both cold and room temperature) and strangers (e.g., in the ventral striatum, middle-insula, ventromedial prefrontal cortex, pregenual cingulate cortex). Cooler temperatures had no effect on brain activity to close others (vs. strangers). Further, physical warmth increased feelings of social connection, even when adjusting for feelings of pleasure, but not vice versa, suggesting physical warmth may have specific effects on feelings of social connection. Results add to an emerging literature on the contribution of physical warmth to social connection and furthers understanding of why and how connecting with others is a basic need for humans. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Neural Correlates of Giving Social Support: Differences Between Giving Targeted Versus Untargeted Support.

OBJECTIVE: Giving support contributes to the link between social ties and health; however, the neural mechanisms are not known. Giving support in humans may rely on neural regions implicated in parental care in animals. The current studies, therefore, assess the contribution of parental care-related neural regions to giving support in humans and, as a further theoretical test, examine whether the benefits of giving targeted support to single, identifiable individuals in need extend to giving untargeted support to larger societal causes. METHODS: For study 1 (n = 45, M (SD) age = 21.98 (3.29), 69% females), participants completed a giving support task, followed by an emotional faces task in the functional magnetic resonance imaging scanner. For study 2 (n = 382, M (SD) age = 43.03 (7.28), 52% females), participants self-reported on their giving support behavior and completed an emotional faces task in the functional magnetic resonance imaging scanner. RESULTS: In study 1, giving targeted (versus untargeted) support resulted in greater feelings of social connection and support effectiveness. Furthermore, greater septal area activity, a region centrally involved in parental care in animals, to giving targeted support was associated with less right amygdala activity to an emotional faces task (r = -.297, 95% confidence interval = -.547 to -.043). Study 2 replicated and extended this association to show that self-reports of giving targeted support were associated with less amygdala activity to a different emotional faces task, even when adjusting for other social factors (r = -.105, 95% confidence interval = -.200 to -.011). Giving untargeted support was not related to amygdala activity in either study. CONCLUSIONS: Results highlight the unique benefits of giving targeted support and elucidate neural pathways by which giving support may lead to health.