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J Asian Nat Prod Res
; 25(5): 429-437, 2023 May.
Article
En
| MEDLINE
| ID: mdl-35930443
Two new monoterpenoid indole alkaloids 3-hydroxylochnerine (1) and 10-hydroxyvinorine (2) were isolated from the roots of Rauvolfia yunnanensis. Their structures were elucidated based on the analysis of spectroscopic data and ECD calculation. Both compounds exhibited potent antimicrobial activity against Bacillus subtilis and Escherichia coli, and their activities were comparable to the well-known antibacterial drug berberine.
Anti-Infective Agents , Rauwolfia , Secologanin Tryptamine Alkaloids , Secologanin Tryptamine Alkaloids/chemistry , Rauwolfia/chemistry , Molecular Structure , Anti-Infective Agents/pharmacology , Anti-Bacterial Agents/pharmacology , Indole Alkaloids