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1.
Pediatr Radiol ; 46(1): 61-6, 2016 Jan.
Article En | MEDLINE | ID: mdl-26216157

BACKGROUND: The three most common elbow fractures classically reported in pediatric orthopedic literature are supracondylar (50-70%), lateral condylar (17-34%), and medial epicondylar fractures (10%), with fractures of the proximal radius (including but not limited to fractures of the radial neck) being relatively uncommon (5-10%). Our experience at a large children's hospital suggests a different distribution. OBJECTIVE: Our goals were (1) to ascertain the frequency of different elbow fracture types in a large pediatric population, and (2) to determine which fracture types were occult on initial radiographs but detected on follow-up. MATERIALS AND METHODS: Review of medical records identified 462 children, median age 6 years and interquartile range for age of 4-8 years (range 0.8-18 years), who were diagnosed with elbow fractures at our institution over a 10-month period. Initial and follow-up radiographs were reviewed in blinded fashion independently by two experienced pediatric musculoskeletal radiologists to identify fracture types on initial and follow-up radiographs. RESULTS: The most common fractures included supracondylar (n = 258, 56%), radial neck (n = 80, 17%), and lateral condylar (n = 69, 15%). Additional fractures were seen on follow-up exams in 32 children. Of these, 25 had a different fracture type than was identified on initial radiographs. The most common follow-up fractures were olecranon (n = 23, 72%), coronoid process (n = 4, 13%) and supracondylar (n = 3, 9%). Olecranon fractures were significantly more common on follow-up radiographs than they were on initial radiographs (n = 33, 7%; P < .0001). Twenty-six children had more than one fracture type on the initial radiograph. The most common fracture combinations were radial neck with olecranon (n = 9) and supracondylar with lateral condylar (n = 9). CONCLUSION: Supracondylar fractures are the most frequent elbow fracture seen initially, followed by radial neck, lateral condylar, and olecranon fractures in a distribution different from what has been historically described. The relatively high frequency of olecranon fractures detected on follow-up speaks to their potentially occult nature. Careful attention to these areas is warranted in children with initially normal radiographs.


Elbow Injuries , Elbow Joint/diagnostic imaging , Radius Fractures/diagnostic imaging , Radius Fractures/epidemiology , Ulna Fractures/diagnostic imaging , Ulna Fractures/epidemiology , Adolescent , Child , Child, Preschool , Comorbidity , Humans , Incidence , Infant , Male , Observer Variation , Ohio/epidemiology , Radiography , Risk Factors , Single-Blind Method
2.
Radiology ; 276(1): 233-42, 2015 Jul.
Article En | MEDLINE | ID: mdl-25654668

PURPOSE: To investigate diagnostic performance and radiation dose with the use of computed tomographic (CT) enterography in children and young adults and to compare reconstruction with filtered back projection (FBP) to that with adaptive iterative dose reduction (AIDR) with three-dimensional (3D) processing. MATERIALS AND METHODS: This retrospective investigation was HIPAA compliant and approved by the institutional review board. Informed consent was waived. CT enterographic examinations performed between October 2008 and June 2009 with FBP and between August 2012 and April 2014 with AIDR 3D in patients who had received histologic evaluation within 45 days of imaging were included. Two reviewers retrospectively and independently evaluated the studies for findings of active inflammation, and diagnostic performance and interreader reliability were assessed. The reference standard was histologic findings. Objective and subjective image quality also was assessed. The size-specific dose estimate was compared between the two groups. Two-sample t tests or analysis of variance tests were performed to assess for differences in diagnostic accuracy, image quality, and radiation dose between the FBP and AIDR 3D examinations. RESULTS: Fifty patients were included in the FBP group (mean age, 14.1 years; range, 8-21 years) and 68 patients were in the AIDR 3D group (mean age, 13.2 years; range, 2-29 years). Sensitivity and specificity for detection of active inflammation were 96% (26 of 27) and 96% (22 of 23), respectively, for the FBP group and 90% (45 of 50) and 89% (16 of 18), respectively, for the AIDR 3D group. Dichotomous interreader reliability (κ) for the entire group was 0.86. The mean size-specific dose estimate for all weights was significantly lower for the AIDR 3D group (6.1 mGy ± 2.1) than that for the FBP group (16.7 mGy ± 5.2; P < .0001). No significant difference was found in objective image noise for soft-tissue structures (P = .2-.8). CONCLUSION: CT enterography is highly accurate for detection of active inflammation in pediatric patients and has excellent interreader reliability. Reduced-dose CT enterography with AIDR 3D allowed substantial dose reduction compared with that used with FBP CT enterographic examinations, while maintaining a high diagnostic performance.


Imaging, Three-Dimensional , Inflammatory Bowel Diseases/diagnostic imaging , Radiation Dosage , Tomography, X-Ray Computed/methods , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Male , Radiographic Image Enhancement , Retrospective Studies , Young Adult
3.
AJR Am J Roentgenol ; 204(1): W95-W103, 2015 Jan.
Article En | MEDLINE | ID: mdl-25539281

OBJECTIVE: The purpose of this study was to determine parents' knowledge about pediatric fluoroscopic procedures and potential risk from ionizing radiation before and after being given an informational brochure. SUBJECTS AND METHODS: We reviewed responses from 120 randomly selected participants who were parents or guardians of pediatric patients undergoing diagnostic fluoroscopic examinations. A questionnaire assessed participants' knowledge of the procedure, radiation exposure, and whether their child had a prior examination before and after receiving an informational brochure. In a feedback survey, participants rated the brochure. A repeated measures mixed model was used to evaluate the effect of the brochure on the participants' knowledge. RESULTS: Participant demographics were women (79%), English speaking (99%), white (90%), and education higher than 12th grade (76%). The median age of patients undergoing the fluoroscopic examination was 4 years. Participant knowledge increased (p < 0.0001) between pre- and postbrochure (least-squares means) for those without a previous examination from 38.3 to 63.4 (total test score) and from 46.3 to 61.8 for those with a prior examination. The proportion of correct answers was higher (p < 0.0001) postbrochure compared with pre-brochure in areas of examination name (99% vs 93%), procedure details (97% vs 87%); use of radiation (100% vs 68%), and radiation dose comparison (79% vs 25%). Overall, 99% (119/120) rated the brochure "good" or "great" (p < 0.0001). CONCLUSION: An informational brochure given to participants before their child's fluoroscopic procedure improved their knowledge of the examination and radiation exposure. No participants refused their child's examination.


Consumer Health Information/statistics & numerical data , Fluoroscopy , Health Literacy/methods , Health Literacy/statistics & numerical data , Pamphlets , Parents/education , Radiology/education , Adult , Child , Child, Preschool , Consumer Health Information/methods , Educational Status , Female , Humans , Infant , Infant, Newborn , Ohio , Parent-Child Relations , Pediatrics/education , Radiology/statistics & numerical data , Young Adult
4.
Pediatr Radiol ; 44(6): 729-37, 2014 Jun.
Article En | MEDLINE | ID: mdl-24473866

BACKGROUND: Prior literature, limited to small case series and case reports, suggests that rotator cuff tears are rare in adolescents. However, we have identified rotator cuff tears in numerous children and adolescents who have undergone shoulder MRI evaluation. OBJECTIVE: The purpose of this study is to describe the prevalence and characteristics of rotator cuff tears in children and adolescents referred for MRI evaluation of the shoulder at a large pediatric hospital and to correlate the presence of rotator cuff tears with concurrent labral pathology, skeletal maturity and patient activity and outcomes. MATERIALS AND METHODS: We reviewed reports from 455 consecutive non-contrast MRI and magnetic resonance arthrogram examinations of the shoulder performed during a 2-year period, and following exclusions we yielded 205 examinations in 201 patients (ages 8-18 years; 75 girls, 126 boys). Rotator cuff tears were classified by tendon involved, tear thickness (partial or full), surface and location of tear (when partial) and presence of delamination. We recorded concurrent labral pathology when present. Physeal patency of the proximal humerus was considered open, closing or closed. Statistical analysis was performed to evaluate for a relationship between rotator cuff tears and degree of physeal patency. We obtained patient activity at the time of injury, surgical reports and outcomes from clinical records when available. RESULTS: Twenty-five (12.2%) rotator cuff tears were identified in 17 boys and 7 girls (ages 10-18 years; one patient had bilateral tears). The supraspinatus tendon was most frequently involved (56%). There were 2 full-thickness and 23 partial-thickness tears with articular-side partial-thickness tears most frequent (78%). Insertional partial-thickness tears were more common (78%) than critical zone tears (22%) and 10 (43%) partial-thickness tears were delamination tears. Nine (36%) patients with rotator cuff tears had concurrent labral pathology. There was no statistically significant relationship between rotator cuff tears and physeal patency (P > 0.05). Most patients were athletes (76%). Five tears were confirmed at surgery. Poor clinical follow-up limited evaluation of patient outcomes. CONCLUSION: Rotator cuff tears can be identified during MRI examination of symptomatic child and adolescent shoulders and often consist of tear patterns associated with repetitive microtrauma in overhead athletic activities or with single traumatic events. Rotator cuff tears are seen throughout the range of skeletal maturity, often coexist with labral tears and typically are found in athletes.


Magnetic Resonance Imaging , Rotator Cuff Injuries , Tendon Injuries/diagnosis , Adolescent , Child , Contrast Media , Female , Gadolinium DTPA , Hospitals, Pediatric , Humans , Male , Prevalence , Tendon Injuries/epidemiology , Triiodobenzoic Acids , United States/epidemiology
5.
Acad Radiol ; 20(9): 1152-61, 2013 Sep.
Article En | MEDLINE | ID: mdl-23931430

RATIONALE AND OBJECTIVES: Efforts to decrease radiation exposure during pediatric high-resolution thoracic computed tomography (HRCT), while maintaining diagnostic image quality, are imperative. The objective of this investigation was to compare organ doses and scan performance for pediatric HRCT using volume, helical, and noncontiguous axial acquisitions. MATERIALS AND METHODS: Thoracic organ doses were measured using 20 metal oxide semiconductor field-effect transistor dosimeters. Mean and median organ doses and scan durations were determined and compared for three acquisition modes in a 5-year-old anthropomorphic phantom using similar clinical pediatric scan parameters. Image noise was measured and compared in identical regions within the thorax. RESULTS: There was a significantly lower dose in lung (1.8 vs 2.7 mGy, P < .02) and thymus (2.3 vs 2.7 mGy, P < .02) between volume and noncontiguous axial modes and in lung (1.8 vs 2.3 mGy, P < .02), breast (1.8 vs 2.6 mGy, P < .02), and thymus (2.3 vs 2.4 mGy, P < .02) between volume and helical modes. There was a significantly lower median image noise for volume compared to helical and axial modes in lung (55.6 vs 79.3 and 70.7) and soft tissue (76.0 vs 111.3 and 89.9). Scan times for volume, helical, and noncontiguous axial acquisitions were 0.35, 3.9, and 24.5 seconds, respectively. CONCLUSION: Volumetric HRCT provides an opportunity for thoracic organ dose and image noise reduction, at significantly faster scanning speeds, which may benefit pediatric patients undergoing surveillance studies for diffuse lung disease.


Radiation Dosage , Radiation Protection/methods , Radiographic Image Interpretation, Computer-Assisted/methods , Radiography, Thoracic/methods , Tomography, X-Ray Computed/methods , Whole-Body Counting , Child, Preschool , Humans , Phantoms, Imaging , Radiographic Image Enhancement/methods , Radiography, Thoracic/instrumentation , Reproducibility of Results , Sensitivity and Specificity , Tomography, X-Ray Computed/instrumentation
6.
Pediatr Radiol ; 43(9): 1117-27, 2013 Sep.
Article En | MEDLINE | ID: mdl-23636537

BACKGROUND: Advanced multidetector CT systems facilitate volumetric image acquisition, which offers theoretic dose savings over helical acquisition with shorter scan times. OBJECTIVE: Compare effective dose (ED), scan duration and image noise using 320- and 64-detector CT scanners in various acquisition modes for clinical chest, abdomen and pelvis protocols. MATERIALS AND METHODS: ED and scan durations were determined for 64-detector helical, 160-detector helical and volume modes under chest, abdomen and pelvis protocols on 320-detector CT with adaptive collimation and 64-detector helical mode on 64-detector CT without adaptive collimation in a phantom representing a 5-year-old child. Noise was measured as standard deviation of Hounsfield units. RESULTS: Compared to 64-detector helical CT, all acquisition modes on 320-detector CT resulted in lower ED and scan durations. Dose savings were greater for chest (27-46%) than abdomen/pelvis (18-28%) and chest/abdomen/pelvis imaging (8-14%). Noise was similar across scanning modes, although some protocols on 320-detector CT produced slightly higher noise. CONCLUSION: Dose savings can be achieved for chest, abdomen/pelvis and chest/abdomen/pelvis examinations on 320-detector CT compared to helical acquisition on 64-detector CT, with shorter scan durations. Although noise differences between some modes reached statistical significance, this is of doubtful diagnostic significance and will be studied further in a clinical setting.


Artifacts , Imaging, Three-Dimensional/instrumentation , Phantoms, Imaging , Radiation Dosage , Radiometry , Tomography, Spiral Computed/instrumentation , Whole Body Imaging/instrumentation , Child , Equipment Design , Equipment Failure Analysis , Humans , Reproducibility of Results , Sensitivity and Specificity , Time Factors
7.
AJR Am J Roentgenol ; 199(5): 1129-35, 2012 Nov.
Article En | MEDLINE | ID: mdl-23096189

OBJECTIVE: The purpose of this study is to determine patient dose estimates for clinical pediatric cardiac-gated CT angiography (CTA) protocols on a 320-MDCT volume scanner. MATERIALS AND METHODS: Organ doses were measured using 20 metal oxide semiconductor field effect transistor (MOSFET) dosimeters. Radiation dose was estimated for volumetrically acquired clinical pediatric prospectively and retrospectively ECG-gated cardiac CTA protocols in 5-year-old and 1-year-old anthropomorphic phantoms on a 320-MDCT scanner. Simulated heart rates of 60 beats/min (5-year-old phantom) and 120 beats/min (1- and 5-year-old phantoms) were used. Effective doses (EDs) were calculated using average measured organ doses and International Commission on Radiological Protection 103 tissue-weighting factors. Dose-length product (DLP) was recorded for each examination and was used to develop dose conversion factors for pediatric cardiac examinations acquired with volume scan mode. DLP was also used to estimate ED according to recently published dose conversion factors for pediatric helical chest examinations. Repeated measures and paired Student t test analyses were performed. RESULTS: For the 5-year-old phantom, at 60 beats/min, EDs ranged from 1.2 mSv for a prospectively gated examination to 4.5 mSv for a retrospectively gated examination. For the 5-year-old phantom, at 120 beats/min, EDs ranged from 3.0 mSv for a prospectively gated examination to 4.9 mSv for a retrospectively gated examination. For the 1-year-old phantom, at 120 beats/min, EDs ranged from 2.7 mSv for a prospectively gated examination to 4.5 mSv for a retrospectively gated examination. CONCLUSION: EDs for 320-MDCT volumetrically acquired ECG-gated pediatric cardiac CTA are lower than those published for conventional 16- and 64-MDCT scanners.


Cardiac-Gated Imaging Techniques , Coronary Angiography/methods , Phantoms, Imaging , Radiation Dosage , Tomography, X-Ray Computed/methods , Body Burden , Calibration , Child, Preschool , Humans , Infant , Prospective Studies , Retrospective Studies
8.
J Bone Joint Surg Am ; 94(18): e136(1-8), 2012 Sep 19.
Article En | MEDLINE | ID: mdl-22992884

BACKGROUND: Neonatal brachial plexus palsy frequently leads to glenohumeral dysplasia if neurological recovery is incomplete. Although glenoid retroversion and glenohumeral subluxation have been well characterized, humeral head deformity has not previously been quantified. Nonetheless, humeral head flattening is described as a contraindication to joint contracture release and external rotation tendon transfers. This study describes a novel technique for objectively quantifying humeral head deformity with use of magnetic resonance (MR) imaging and correlates the humeral head deformity with clinical and radiographic outcomes following joint rebalancing surgery. METHODS: Magnetic resonance images of thirty-two children (age, 0.7 to 11.5 years) with neonatal brachial plexus palsy were retrospectively reviewed. Passive shoulder external rotation and Mallet scores were reviewed before joint rebalancing surgery and at a minimum clinical follow-up interval of two years. The humeral head skewness ratio on preoperative and postoperative axial MR images was defined as the ratio of anterior to posterior humeral head area, and this ratio was compared between affected and unaffected shoulders and with the glenoid version angle, posterior subluxation of the humeral head, and clinical parameters before and after surgery with use of paired t tests and Spearman correlation. Intraobserver and interobserver reliability of MR image measurements was determined. RESULTS: Measurements of the skewness ratio on the affected side had moderate to substantial intraobserver reliability (0.53 to 0.72) and substantial interobserver reliability (0.65 to 0.71). Preoperatively, the skewness ratio of the affected humeral head (mean, 0.76; range, 0.54 to 1.03) differed significantly from the ratio in the contralateral shoulder (p<0.05) and was significantly associated with the glenoid version angle (p<0.05) and posterior subluxation of the humeral head (p<0.05). Remodeling of the affected humeral head was observed postoperatively, with a significant improvement in the skewness ratio (p<0.05). However, there were no significant correlations between the preoperative skewness ratio and postoperative clinical outcomes. CONCLUSIONS: Humeral head deformity in neonatal brachial plexus palsy correlated with other measures of glenohumeral dysplasia and could be reliably and objectively quantified on MR imaging with use of the skewness ratio. The humeral head deformity can remodel following joint rebalancing surgery, and such a deformity alone does not preclude a successful outcome after surgical attempts to restore glenohumeral congruity.


Birth Injuries/epidemiology , Brachial Plexus Neuropathies/epidemiology , Echo-Planar Imaging/methods , Humeral Head/abnormalities , Joint Deformities, Acquired/epidemiology , Age Distribution , Birth Injuries/diagnosis , Birth Injuries/surgery , Brachial Plexus Neuropathies/diagnosis , Brachial Plexus Neuropathies/surgery , Child , Child, Preschool , Cohort Studies , Comorbidity , Female , Follow-Up Studies , Humans , Humeral Head/pathology , Incidence , Infant , Infant, Newborn , Joint Deformities, Acquired/diagnosis , Joint Deformities, Acquired/surgery , Male , Orthopedic Procedures/methods , Physical Examination/methods , Range of Motion, Articular/physiology , Recovery of Function , Retrospective Studies , Risk Assessment , Severity of Illness Index , Sex Distribution , Shoulder Dislocation/diagnosis , Shoulder Dislocation/epidemiology , Shoulder Dislocation/surgery , Treatment Outcome
9.
J Pediatr Ophthalmol Strabismus ; 49(4): 211-4; quiz 210, 215, 2012.
Article En | MEDLINE | ID: mdl-22329551

PURPOSE: Strabismus surgery dosages used in children with various neurodevelopmental disorders have been the subject of controversy. Few data have been reported regarding surgical results in individuals with Down syndrome (DS). METHODS: A retrospective, case-control study was performed in which children with DS and previous bilateral medial rectus recession surgery were matched with similar control patients without DS. Surgical results were compared using a random coefficients model for repeated measurements for each group. RESULTS: Sixteen patients with DS were matched with 16 control patients. Mean preoperative esotropia was 28.4 prism diopters (PD) in the DS group and 27.9 PD in the control group. No significant difference was found in surgical dosages between the two groups (P = .2402). Median surgical dosage was 4.4 mm in the DS group and 4.5 mm in the control group. Preoperative and 4-month and 24-month postoperative mean angles of esotropia were not different between groups (P = .8050). The 4-month postoperative mean angles of esotropia for the DS and control groups were 3.15 and 2.66 PD, respectively. The 24-month mean angles of esotropia for the DS and control groups were 7.09 and 6.60 PD, respectively. CONCLUSION: Standard bilateral medial rectus recession surgical dosages need not be modified for individuals with DS.


Down Syndrome/surgery , Esotropia/surgery , Oculomotor Muscles/surgery , Ophthalmologic Surgical Procedures , Case-Control Studies , Child , Child, Preschool , Down Syndrome/physiopathology , Esotropia/physiopathology , Female , Humans , Male , Oculomotor Muscles/physiopathology , Outcome Assessment, Health Care , Postoperative Period , Retrospective Studies , Treatment Outcome , Vision, Binocular/physiology
10.
AJR Am J Roentgenol ; 197(1): W153-8, 2011 Jul.
Article En | MEDLINE | ID: mdl-21700978

OBJECTIVE: The clinical course of juvenile dermatomyositis (JDMS) is unpredictable. MRI is used to determine muscle biopsy site and to monitor disease activity. It is unknown whether soft-tissue features on MRI obtained at diagnosis correlate with clinical outcome. The purpose of our study is to determine whether initial MRI findings in the pelvis and thighs in children with JDMS can predict clinical disease course. MATERIALS AND METHODS: Forty-five children (31 girls and 14 boys; median age, 6 years; range, 1-18 years) with clinically diagnosed biopsy-proven JDMS and at least 24 months of clinical follow-up were included. Clinical outcome was categorized as limited or chronic disease, according to the established Crowe clinical classification scheme. Pretreatment MRI examinations of the pelvis and thighs were evaluated for signal abnormalities of muscle and fascia and reticulated signal changes in subcutaneous fat; associations with clinical outcome were examined. RESULTS: Twenty-two patients had limited disease and 23 had chronic disease. Signal intensity ranged from normal (n = 3) to floridly increased in all muscle compartments (n = 17). Muscle and fascial involvement were not associated with clinical outcome. Controlling for duration of symptoms, the adjusted odds of progressing to chronic disease were higher for patients with abnormal subcutaneous fat signal than for those with normal fat signal (odds ratio, 9.0; 95% CI, 1.5-53.5; p < 0.02). CONCLUSION: MRI findings of muscle or fascia involvement do not predict clinical outcome in children with newly diagnosed JDMS. Abnormal subcutaneous fat signal appears to have a significant association with a more aggressive chronic disease course.


Dermatomyositis/pathology , Magnetic Resonance Imaging/methods , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , Prognosis , Reproducibility of Results , Sensitivity and Specificity , Statistics as Topic
11.
Radiology ; 259(3): 793-801, 2011 Jun.
Article En | MEDLINE | ID: mdl-21467249

PURPOSE: To describe nationwide trends and factors associated with the use of computed tomography (CT) in children visiting emergency departments (EDs) in the United States between 1995 and 2008. MATERIALS AND METHODS: This study was exempt from institutional review board oversight. Data from the 1995-2008 National Hospital Ambulatory Medical Care Survey were used to evaluate the number and percentage of visits associated with CT for patients younger than 18 years. A mean of 7375 visits were sampled each year. Data were subcategorized according to multiple patient and hospital characteristics. The Rao-Scott χ(2) test was performed to determine whether CT use was similar across subpopulations. RESULTS: From 1995 to 2008, the number of pediatric ED visits that included CT examination increased from 0.33 to 1.65 million, a fivefold increase, with a compound annual growth rate of 13.2%. The percentage of visits associated with CT increased from 1.2% to 5.9%, a 4.8-fold increase, with a compound annual growth rate of 12.8%. The number of visits associated with CT at pediatric-focused and non-pediatric-focused EDs increased from 14,895 and 316,133, respectively, in 1995 to 212,716 and 1,438,413, respectively, in 2008. By the end of the study period, top chief complaints among those undergoing CT included head injury, abdominal pain, and headache. CONCLUSION: Use of CT in children who visit the ED has increased substantially and occurs primarily at non-pediatric-focused facilities. This underscores the need for special attention to this vulnerable population to ensure that imaging is appropriately ordered, performed, and interpreted.


Emergency Service, Hospital/statistics & numerical data , Tomography, X-Ray Computed/statistics & numerical data , Adolescent , Chi-Square Distribution , Child , Child, Preschool , Female , Health Care Surveys , Humans , Infant , Infant, Newborn , Male , United States
12.
AJR Am J Roentgenol ; 196(4): W433-7, 2011 Apr.
Article En | MEDLINE | ID: mdl-21427308

OBJECTIVE: The retropharyngeal lymph nodes are the least well-described portion of the Waldeyer ring. Originally described as occurring in medial and lateral groups, reports have described only the presence of lateral nodes in children. We have seen cases of MRI sleep studies in children with obstructive sleep apnea (OSA) in which lateral and medial retropharyngeal lymph nodes are present and have been misinterpreted. Our purpose is to describe the frequency and appearance of retropharyngeal lymph nodes in children with and without OSA. MATERIALS AND METHODS: Axial and sagittal T2-weighted MRI scans were reviewed in 150 children with OSA and 150 control subjects without OSA, who underwent imaging for other indications. The presence, size, and location of the retropharyngeal lymph nodes were evaluated. Retropharyngeal lymph nodes were evaluated for frequency of medial nodes, frequency of lateral nodes, size as indicated by the anterior-to-posterior diameter, laterality (bilateral or unilateral), and superior-to-inferior location compared with the cervical vertebral body level. Analyses were performed using the chi-square or Fisher's exact test (for categorical data) and generalized linear model or two-sample Wilcoxon's Mann-Whitney test (for continuous data). RESULTS: Lateral retropharyngeal lymph nodes were common in both children with OSA (137/150 [91.3%]) and children without OSA (146/150 [97.3%]). Medial retropharyngeal lymph nodes occurred not uncommonly in both children with OSA (32/150 [21.3%]) and those without OSA (26/150 [17.3%]). Lateral retropharyngeal lymph nodes were more commonly bilateral (95% CI, 88.4-97.4%; p < 0.0001) and located at the skull base (C1) or C1-C2 level (99%; p < 0.0001). Medial retropharyngeal lymph nodes were more commonly unilateral (95% CI, 71.9-84.6%; p < 0.0004) and located at the C2-C3 level (95% CI, 78.13-84.62%; p < 0.0001). There were no statistically significant differences in the proportion of medial or lateral retropharyngeal lymph nodes in the OSA group compared with the control group. CONCLUSION: Retropharyngeal lymph nodes are seen commonly in children in both lateral (95% CI, 91.3-97.3%) and medial (95% CI, 17.3-21.3%) locations. Media nodes are present more frequently than previously described. Such nodes occur almost equally frequently in populations with and without OSA. Retropharyngeal lymph nodes should be considered normal in children and not be interpreted as abnormal or misdiagnosed.


Lymph Nodes/pathology , Magnetic Resonance Imaging/methods , Sleep Apnea, Obstructive/pathology , Adolescent , Case-Control Studies , Chi-Square Distribution , Child , Child, Preschool , Diagnosis, Differential , Diagnostic Errors , Female , Humans , Linear Models , Lymph Nodes/anatomy & histology , Male , Pharynx , Reference Values , Statistics, Nonparametric
13.
AJR Am J Roentgenol ; 196(2): 454-60, 2011 Feb.
Article En | MEDLINE | ID: mdl-21257900

OBJECTIVE: Turner syndrome affects one in 2,500 girls and women and is associated with cardiovascular anomalies. Visualizing the descending thoracic aorta in adults with Turner syndrome with echocardiography is difficult. Therefore, cardiac MRI is the preferred imaging modality for surveillance. Our goals were to use cardiac MRI describe the spectrum and frequency of cardiovascular abnormalities and to evaluate aortic dilatation and associated abnormalities in pediatric patients with Turner syndrome. MATERIALS AND METHODS: The cases of 51 patients with Turner syndrome (median age, 18.4 years; range, 6-36 years) were evaluated with cardiac MRI. The characteristics assessed included aortic structure, elongation of the transverse aortic arch, aortic diameter at multiple locations, and coarctation of the aorta (CoA). Additional evaluations were made for presence of bicuspid aortic valve (BAV), and partial anomalous pulmonary venous return (PAPVR). Associations between the cardiac MRI data and the following factors were assessed: age, karyotype, body surface area, blood pressure, and ventricular sizes and function. RESULTS: Sixteen patients (31.4%) had elongation of the transverse aortic arch, eight (15.7%) had CoA, 20 (39.2%) had BAV, and eight (15.7%) had PAPVR. Aortic dilatation was most common at the aortic sinus (30%). Elongation of the transverse aortic arch was associated with CoA (p < 0.01) and BAV (p < 0.05). Patients with elongation of the transverse aortic arch had dilated aortic sinus (p < 0.05). Patients with PAPVR had increased right heart mass (p < 0.05), increased ratio of main pulmonary artery to aortic valve blood flow (p = 0.0014), and increased right ventricular volume (p < 0.05). CONCLUSION: Cardiovascular anomalies in pediatric patients with Turner syndrome include aortic abnormalities and PAPVR. The significant association between elongation of the transverse aortic arch and CoA, BAV, and aortic sinus dilatation may contribute to increased risk of aortic dissection. The presence of PAPVR can be hemodynamically significant. These findings indicate that periodic cardiac MRI screening of persons with Turner syndrome is beneficial.


Cardiovascular Abnormalities/diagnosis , Cardiovascular Abnormalities/epidemiology , Turner Syndrome/epidemiology , Adolescent , Adult , Child , Comorbidity , Electrocardiography , Female , Humans , Hypertension/epidemiology , Image Enhancement/methods , Incidence , Magnetic Resonance Angiography , Magnetic Resonance Imaging , Prevalence , Retrospective Studies , Young Adult
14.
Radiology ; 258(1): 164-73, 2011 Jan.
Article En | MEDLINE | ID: mdl-21115875

PURPOSE: To identify nationwide trends and factors associated with the use of computed tomography (CT) in the emergency department (ED). MATERIALS AND METHODS: This study was exempt from institutional review board approval. Data from the 1995-2007 National Hospital Ambulatory Medical Care Survey were used to evaluate the numbers and percentages of ED visits associated with CT. A mean of 30 044 visits were sampled each year. Data were also subcategorized according to multiple patient and hospital characteristics. The Rao-Scott χ(2) test was performed to determine whether CT use was similar across subpopulations. Data were evaluated according to exponential and logistic growth models. RESULTS: From 1995 to 2007, the number of ED visits that included a CT examination increased from 2.7 million to 16.2 million, constituting a 5.9-fold increase and a compound annual growth rate of 16.0%. The percentage of visits associated with CT increased from 2.8% to 13.9%, constituting a 4.9-fold increase and a compound annual growth rate of 14.2%. The exponential growth model provided the best fit for the trend in CT use. CT use was greater in older patients, white patients, patients admitted to the hospital, and patients at facilities in metropolitan regions. By the end of the study period, the top chief complaints among those who underwent CT were abdominal pain, headache, and chest pain. The percentage of patient visits associated with CT for all evaluated chief complaints increased-most substantially among those who underwent CT for flank, abdominal, or chest pain. CONCLUSION: Use of CT has increased at a higher rate in the ED than in other settings. The overall use of CT had not begun to taper by 2007.


Emergency Service, Hospital/statistics & numerical data , Tomography, X-Ray Computed/statistics & numerical data , Chi-Square Distribution , Health Care Surveys , Humans , Logistic Models , United States
15.
AJR Am J Roentgenol ; 195(4): 1021-5, 2010 Oct.
Article En | MEDLINE | ID: mdl-20858834

OBJECTIVE: Increased cartilage T2 relaxation time is thought to be an early marker of disease progression in juvenile idiopathic arthritis, because it can identify microstructural changes before damage becomes visible. The purpose of this study was to investigate longitudinal changes in T2 relaxation time mapping (i.e., T2 map) in children with early juvenile idiopathic arthritis and to compare with changes in clinical assessments. SUBJECTS AND METHODS: Twenty children (age range, 6.4-16 years) with early juvenile idiopathic arthritis completed at least four evaluations with T2 maps and clinical assessments: at enrollment, at 3 months, and at 1, 2, and 3 years. Sagittal T2 maps of distal femoral cartilage were generated, a region of interest was selected, and a T2 relaxation time profile was generated. The area under the curve from the T2 profile (i.e., T2 value) was correlated with patient age and sex and the following clinical assessments: total knee score, Childhood Health Assessment Questionnaire, physician global assessment, parent global assessment, and total number of active joints. RESULTS: There was a significant increase in mean T2 values from 3 months to 2 years (p < 0.05). There was a significant decrease in mean Childhood Health Assessment Questionnaire values between enrollment and 2 years (p < 0.05) and a significant decrease in parent global assessment, physician global assessment, total number of active joints, and total knee score values between enrollment and 1 year (p < 0.05). There were no statistically significant correlations between T2 values and patient age, sex, or clinical assessments. CONCLUSION: In patients with early juvenile idiopathic arthritis, T2 maps showed increased T2 values from the 3-month to 2-year follow-up, during which time the clinical assessments improved. This increase likely represents progressive microstructural changes, even though clinical symptoms improved with treatment.


Arthritis, Juvenile/pathology , Cartilage, Articular/pathology , Magnetic Resonance Imaging , Adolescent , Child , Female , Femur , Humans , Longitudinal Studies , Male , Time Factors
16.
J Pediatr Orthop ; 30(6): 617-23, 2010 Sep.
Article En | MEDLINE | ID: mdl-20733430

BACKGROUND: Operating room (OR) human traffic has been implicated as a cause of surgical site infection. We first observed the normal human traffic pattern in our Pediatric Orthopedic ORs, and then examined the effect of surveillance on that traffic pattern. METHODS: This study consisted of 2 phases: phase I sought to observe the OR traffic pattern (number of door swings, maximum and minimum number of OR personnel, number of OR personnel at 30-minute intervals, or changes in nursing, anesthesia, or surgeon staff) during surgical cases without OR personnel being notified, and for phase II, the same traffic pattern was monitored with their knowledge. RESULTS: Two thousand four hundred forty-two minutes of surgical time were observed in phase I, and 1908 minutes were observed in phase II. There was no difference (P=0.06) in the time between door swings between phase I (1.39 min) and phase II (1.70 min), no difference (P=1.000) in the maximum number of people in the OR between phase I (11.5 people, range: 7-15 people) and phase II (11.5 people, range: 8-20 people), and no difference (P=1.000) in the minimum number of people in the OR between phase I (4.67 people, range: 4-6 people) and phase II (4.71 people, range: 3-6 people). There was a difference in the time between door swings (P=0.03) and maximum number of people in the OR (P=0.005) based on the length of the surgery (less or more than 120 min). There was no difference in the time between door swings (P=0.11), but there was a difference in the maximum number of people in the OR (P=0.002) based on type of surgery (spine vs. others). CONCLUSIONS: There was no role of surveillance of human traffic in the OR. To achieve any change in the OR traffic pattern, monitoring alone may not be sufficient; other novel techniques or incentives may need to be considered.


Operating Rooms/organization & administration , Orthopedics/organization & administration , Surgical Wound Infection/prevention & control , Humans , Pediatrics , Personnel, Hospital/statistics & numerical data , Prospective Studies , Time Factors
17.
J Pediatr Orthop ; 30(3): 224-30, 2010.
Article En | MEDLINE | ID: mdl-20357586

BACKGROUND: The medial patellofemoral ligament (MPFL), a chief medial restraint preventing lateral patellar dislocation, often is reconstructed in children with recurrent dislocation. The femoral MPFL attachment can be difficult to delineate at surgery. Therefore, the origin of the medial collateral ligament (MCL) frequently is used to approximate the reattachment site. The purpose of our study was to compile normative data from MR imaging examinations over different patient ages, to determine the effect of growth on the relationship of the MCL origin site to the distal femoral physis and medial femoral condyle (MFC). SUBJECTS AND METHODS: This HIPAA-compliant study was IRB approved. Informed consent requirement was waived. Three hundred knee MR imaging examinations (143 boys, 157 girls, 0-20 y) were evaluated. MCL origin to femoral physis distance, MFC height, and MCL origin-physis distance: MFC height ratio (MCL:MFC ratio) were calculated. Relationships between these values and age, gender, and physeal patency were assessed using linear regression models. RESULTS: With physeal patency, MCL origin-physis distance was significantly associated with increasing age in boys (P=0.0394), and trended toward significance in girls (P=0.0557). Distance increased 0.01 cm/y in both genders. MFC height increased 0.15 cm/y in boys and 0.13 cm/y in girls (P<0.0001). MCL:MFC ratio decreased 0.01/y (P<0.0001). With physeal closure, no significant change was measured for any variable. CONCLUSIONS: During growth, there are statistically significant, albeit minimal, changes of the MCL origin-physis distance and MFC height. As these changes are essentially negligible, no adjustment for age is needed during restorative MPFL surgery in growing children. CLINICAL RELEVANCE: As there is neglible change in location of the origin of the MCL relative to the distal femoral physis during skeletal growth in both boys and girls, no adjustment for patient age is necessary when using the origin of the MCL as a landmark to locate the site of femoral reattachment of a disrupted MPFL.


Femur/growth & development , Knee Joint/anatomy & histology , Magnetic Resonance Imaging/methods , Patellar Ligament/anatomy & histology , Adolescent , Age Factors , Child , Child, Preschool , Epiphyses/anatomy & histology , Female , Humans , Infant , Knee Joint/surgery , Male , Patellar Dislocation/surgery , Patellar Ligament/surgery , Plastic Surgery Procedures/methods , Retrospective Studies , Sex Factors , Young Adult
18.
Pediatr Radiol ; 40(7): 1190-6, 2010 Jul.
Article En | MEDLINE | ID: mdl-20012949

BACKGROUND: The bare spot of the glenoid fossa is a normal cartilage defect seen frequently in adults. It has been used on arthroscopy as a landmark for the center of the glenoid fossa. There are no reports of this variant in children, but we have noted it on some pediatric clinical shoulder MRI studies. OBJECTIVE: Our main purpose is to evaluate the incidence of the bare spot in children and define location and MRI features. MATERIALS AND METHODS: Shoulder MRI studies (total 570) from 2004 to 2008 were reviewed. Children were divided into two age groups: group 1, 0-10 years (n = 200), group 2, 11-20 years (n = 370). RESULTS: A total of 12 bare spots (2.1%) were identified; all were seen in group 2. Eight (67%) were central and four were eccentric in the glenoid fossa. All showed a well-marginated focal cartilage defect containing hyperintense joint fluid or contrast agent. Three also had air. CONCLUSION: The bare spot is seen in children. The absence in children younger than 10 years and the low incidence in the second decade support the proposed acquired nature. Familiarity with this finding is important so as not to misinterpret it as a pathologic condition.


Cartilage Diseases/epidemiology , Cartilage Diseases/pathology , Cartilage, Articular/pathology , Magnetic Resonance Imaging/statistics & numerical data , Shoulder Joint/pathology , Adolescent , Child , Child, Preschool , Female , Humans , Incidence , Male , Ohio/epidemiology , Reproducibility of Results , Sensitivity and Specificity
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