1.
Open Forum Infect Dis
; 9(9): ofac428, 2022 Sep.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36119959
RESUMEN
Microbes unculturable in vitro remain diagnostically challenging, dependent historically on clinical findings, histology, or targeted molecular detection. We applied whole-genome sequencing directly from tissue to diagnose infections with mycobacteria (leprosy) and parasites (coenurosis). Direct pathogen DNA sequencing provides flexible solutions to diagnosis of difficult pathogens in diverse contexts.