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Indian J Pediatr ; 75(9): 953-5, 2008 Sep.
Article En | MEDLINE | ID: mdl-18810359

The posterior/potentially reversible encephalopathy syndrome is a unique syndrome encountered commonly in hypertensive encephalopathy. A 13-year-old boy presented with of intermittent high grade fever, throbbing headache and non-projective vomiting for 5 days. The patient had a blood pressure of 120/80 mmHg but fundoscopy documented grade 3 hypertensive retinopathy. The patient improved symptomatically following conservative management. However, on the 5(th) post-admission day headache reappeared, and blood pressure measured at that time was 240/120 mmHg. Neuroimaging suggested white matter abnormalities. Search for the etiology of secondary hypertension led to the diagnosis of pheochromocytoma. Repeated MRI after successful surgical excision of the tumor patient showed reversal of white matter abnormalities. Reversible leucoencephalopathy due to pheochromocytoma have not been documented in literature previously.


Adrenal Gland Neoplasms/complications , Brain Diseases/etiology , Hypertensive Encephalopathy/etiology , Magnetic Resonance Imaging/adverse effects , Pheochromocytoma/complications , Adolescent , Adrenal Gland Neoplasms/diagnosis , Adrenal Gland Neoplasms/therapy , Brain Diseases/pathology , Fever/etiology , Headache/etiology , Humans , Hypertensive Encephalopathy/diagnosis , Hypertensive Encephalopathy/therapy , Male , Pheochromocytoma/diagnosis , Pheochromocytoma/therapy , Syndrome
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