RESUMEN
We reported on an all-solid-state double Nd:YAG slab laser. The laser was based on two diode end-pumped Nd:YAG slabs and a stable-unstable hybrid resonator. A cw output of 189 W and an average Q-switched output of 169 W at 10 kHz with an M(2) factor of 1.5 in the slow direction and 1.7 in the fast direction were obtained. We demonstrated efficient near-field frequency doubling by imaging the one-dimensional top-hat near-field to a lithium triborate frequency doubler. We obtained 93 W green light at 10 kHz with a pulse width of 10.7 ns. The efficiency of second-harmonic generation was up to 57%.
Asunto(s)
Láseres de Semiconductores , Neodimio , Procesamiento de Señales Asistido por Computador/instrumentación , Amplificadores Electrónicos , Diseño de Equipo , Análisis de Falla de EquipoRESUMEN
We demonstrate a compact, efficient Nd:YVO(4) stable-unstable hybrid slab oscillator that was partially end pumped at 880 nm. A maximum output power of 165 W at 1064 nm was obtained with an optical-to-optical efficiency from absorbed pump power to laser output of up to 60% and a slope efficiency of up to 66%. The beam propagation factors M(2) were 1.7 in the stable direction and 1.4 in the unstable direction without sidelobes.
RESUMEN
We have developed a novel electro-optic Q-switched diode-end-pumped solid slab laser that combines high energy, short pulse width, high repetition rates, and diffraction-limited beam quality. With two partially end-pumped Nd:YLF slabs and a 100 mm long off-axis positive branch stable-unstable oscillator, 24.2 mJ, 7.1 ns electro-optic Q-switched pulse at 1 kHz repetition rate with a beam quality of M(x)(2)=1.4 and M(y)(2)=1.3 was generated. The peak power reached 3.5 MW. Efficient external second-harmonic generation was achieved by use of lithium triborate with low peak-power intensity.
RESUMEN
We demonstrate a diode-pumped electro-optical Q-switched slab laser with a high optical efficiency, high pulse energy, and short pulse width with two Nd:YLF crystals inside one resonator. The single compact slab resonator can generate a 1D top-hat beam at both the far field and the near field. With a slab-geometry-design lithium triborate (LBO) crystal, efficient critical phase-matching second-harmonic generation for a 1D top-hat beam with multiple transverse modes is achieved.
RESUMEN
BACKGROUND: Pulmonary edema caused by increased microvascular permeability is an important feature of lung ischemia-reperfusion (I/R) injury. METHODS: We investigated the impact of co-aerosolized prostaglandin (PG)I(2) and the 3',5-cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase inhibitor rolipram on microvascular leakage following I/R injury. Buffer-perfused rabbit lungs were exposed to 270 minutes of warm ischemia while anoxic ventilation and a positive intravascular pressure were maintained. RESULTS: On reperfusion, a massive increase of the capillary filtration coefficient and severe edema formation were noted, whereas microvascular pressures displayed only minor changes. Short-time aerosolization of subthreshold doses of either rolipram (33 microg) or PGI(2) (2.6 microg) at the beginning of ischemia did not attenuate the leakage response, whereas the co-aerosolization of both agents largely blocked any permeability increase and edema formation, independent of hemodynamic effects. The same was true when the co-aerosolization was undertaken before onset of ischemia. Similarly, the intravascular administration of rolipram and PGI(2) showed a synergistic reduction of I/R-induced vascular leak but demanded 10-fold higher doses. Intravascular release of cAMP was markedly enhanced on combined PGI(2)-rolipram administration but depended on the mode of delivery of these agents. CONCLUSIONS: Low doses of aerosolized prostacyclin and rolipram synergistically protect against severe lung I/R injury and can be used independently of lung perfusion. This strategy may be suitable for an improvement of organ preservation in lung transplantation including early management of non-heart-beating donors.
