[The Russian version of Coma Recovery Scale-revised - a standardized method for assessment of patients with disorders of consciousness]. / Russkoiazychnaia versiia peresmotrennoi shkaly vosstanovleniia posle komy - standartizirovannyi metod otsenki patsientov s khronicheskimi narusheniiami soznaniia.

The authors officially present for the first time the Russian version of Coma Recovery Scale-Revised (CRS-R). Today CRS-R is the only validated scale in Russian for assessment of patients with chronic disorders of consciousness (DOC). The study showed high consistency for different researchers, high sensitivity in the evaluation of patients over time as well as high concurrent validity. This article contains the text of the scale and recommendations how to use CRS-R and interpret the data. Presented version of the CRS-R is recommended for use in DOC patients. Russian version of the CRS-R is a standardized, comprehensive and systematic approach to the examination and assessment of patients with chronic DOS. It ensures the standard approach to examination and assessment that warrants the accuracy and homogeneity of the obtained results.

[Pharmacological neuroprotection in stroke in clinical practice: new perspectives]. / Farmakologicheskaia neiroprotektsiia pri ishemicheskom insul'te v real'nykh klinicheskikh usloviiakh.

Despite recent advances in acute stroke care, clinical armamentarium against stroke remains limited. Furthermore, highly effective approaches to stroke treatment, such as systemic reperfusion and mechanical thrombectomy, cannot be performed in the majority of patients. Neuroprotective strategies, i.e. prevention of irreversible cell damage due to the ischemia, may improve stroke outcomes. However, only few pharmacological agents demonstrated clinical efficacy. Citicoline is an endogenous mononucleotide with neuroprotective effect and established clinical safety and tolerability, which effectiveness in acute stroke was studied in several large, well-controlled trials. Recent meta-analysis confirmed benefit of citicoline treatment in terms of increase of chance for better recovery of functional independence compared to placebo. Maximal effect of citicoline is seen when it is administered as soon as possible after stroke onset in patients who are not eligible for reperfusion therapy.

[Introduction of tele-medical electrocardiographic system in regional general hospital]. / Opyt vnedreniia telemeditsinskoi élektrokardiograficheskoi sistemy v oblastnoi mnogoprofil'noi klinicheskoi bol'nitse.

The paper reviews the experience in setting up and functioning of telemedical electrocardiographic system in a regional hospital with utilization of current potential of telephone ECG transmission-reception: individual ECG registers-transmitters including devices with "a reverse loop". It is shown that ECG registration by patients themselves with its transmission by telephone facilitates diagnosis of rare paroxysmal conditions and follow-up of cardiological outpatients. Changes in the number of ECGs made for 25 years in the regional center of remote cardiological diagnosis is analysed.