RESUMEN
Introducción y objetivos: El diagnóstico y manejo terapéutico de pacientes con cardiopatías congénitas se basa en gran medida en los resultados de la ecocardiografía. Las diferentes técnicas de fusión de imagen han supuesto un reciente avance en la obtención de imágenes cardíacas. Nuestro objetivo ha sido el de evaluar la viabilidad de la fusión de la tomografía computarizada (TC) y la ecocardiografía transtorácica (ETT) 3D en niños y adultos con cardiopatías congénitas. Métodos: Se incluyeron de forma prospectiva 13 pacientes con cardiopatías congénitas y 1 paciente con corazón normal los cuales se sometieron a TC y ETT 3D como parte de su seguimiento habitual. Se describieron los pasos necesarios para completar el proceso de fusión (alineación, puntos de referencia y superposición), la navegación y la evaluación de las imágenes. Resultados: La edad media fue de 9,5 años [2,7-15,7], el 57% eran varones y la superficie corporal media fue de 0,9 m2 [0,6-1,7]. Se clasificaron las cardiopatías como simples (n=4, 29%), moderadas (n=4, 29%) o complejas (n=6, 42%). La fusión 3D ETT-TC fue exitosa en todos los pacientes. La mediana del tiempo total para completar el proceso de fusión fue de 735 segundos [628-1163], sin diferencias significativas según el grado de complejidad de la cardiopatía. Los puntos de referencia se modificaron significativamente en las cardiopatías congénitas complejas. Conclusiones: La técnica de fusión 3D ETT-TC en una población de niños y adultos con diversas cardiopatías congénitas es viable y precisa según demostramos. La visualización simultánea de diferentes estructuras cardíacas podría ayudar a comprender las características anatómicas de las cardiopatías congénitas sin limitaciones en cuanto a la edad, el peso o la complejidad.(AU)
Introduction and objectives: Diagnosis, management, and surgical decision-making in children and adults with congenital heart disease are largely based on echocardiography findings. A recent development in cardiac imaging is fusion of different imaging modalities. Our objective was to evaluate the feasibility of computed tomography (CT) and 3-dimensional (3D) transthoracic echocardiography (TTE) fusion in children and adults with congenital heart disease. Methods: We prospectively included 14 patients, 13 of whom had congenital heart disease, and who underwent both CT and 3D TTE as part of their usual follow-up. We described the steps required to complete the fusion process (alignment, landmarks, and superimposition), navigation, and image evaluation. Results: Median age was 9.5 [2.7-15.7] years, 57% were male, and median body surface area was 0.9 m2 [0.6-1.7]. Congenital heart disease was classified as simple (n=4, 29%), moderate (n=4, 29%), or complex (n=6, 42%). 3D TTE-CT fusion was successful in all patients. Median total time to complete the fusion process was 735 [628-1163] seconds, with no significant difference according to the degree of complexity of the defects. Landmarks were significantly modified in complex congenital heart disease. Conclusions: We established the feasibility and accuracy of 3D TTE-CT fusion in a population of children and adults with a variety of congenital heart diseases. The simultaneous visualization of many intracardiac structures may help to understand the anatomical features of congenital heart disease without limitations regarding age, weight, or complexity of the congenital defects.(AU)
Asunto(s)
Humanos , Masculino , Femenino , Cardiopatías Congénitas , Tomografía Computarizada por Rayos X , Ecocardiografía , Diagnóstico por Imagen , CardiologíaRESUMEN
INTRODUCTION AND OBJECTIVES: Diagnosis, management, and surgical decision-making in children and adults with congenital heart disease are largely based on echocardiography findings. A recent development in cardiac imaging is fusion of different imaging modalities. Our objective was to evaluate the feasibility of computed tomography (CT) and 3-dimensional (3D) transthoracic echocardiography (TTE) fusion in children and adults with congenital heart disease. METHODS: We prospectively included 14 patients, 13 of whom had congenital heart disease, and who underwent both CT and 3D TTE as part of their usual follow-up. We described the steps required to complete the fusion process (alignment, landmarks, and superimposition), navigation, and image evaluation. RESULTS: Median age was 9.5 [2.7-15.7] years, 57% were male, and median body surface area was 0.9 m2 [0.6-1.7]. Congenital heart disease was classified as simple (n=4, 29%), moderate (n=4, 29%), or complex (n=6, 42%). 3D TTE-CT fusion was successful in all patients. Median total time to complete the fusion process was 735 [628-1163] seconds, with no significant difference according to the degree of complexity of the defects. Landmarks were significantly modified in complex congenital heart disease. CONCLUSIONS: We established the feasibility and accuracy of 3D TTE-CT fusion in a population of children and adults with a variety of congenital heart diseases. The simultaneous visualization of many intracardiac structures may help to understand the anatomical features of congenital heart disease without limitations regarding age, weight, or complexity of the congenital defects.
Asunto(s)
Ecocardiografía Tridimensional , Cardiopatías Congénitas , Niño , Adulto , Humanos , Masculino , Femenino , Cardiopatías Congénitas/diagnóstico por imagen , Cardiopatías Congénitas/cirugía , Ecocardiografía/métodos , Corazón/diagnóstico por imagen , Ecocardiografía Tridimensional/métodos , Tomografía Computarizada por Rayos XRESUMEN
Although substantial progress has been made in recent decades in reducing mortality and performing optimal revascularization in patients with myocardial infarction, ischaemic heart disease, including acute coronary syndrome, remains the leading cause of mortality worldwide. One of the remaining challenges is to better detect, prevent and treat extended myocardial damage despite angiographically optimal revascularization. Several indices are available in clinical practice to evaluate myocardial damage, infarct size and potential myocardial recovery. These indices are divided into two categories: non-invasive, generally performed after revascularization; and invasive, performed during the revascularization procedure. They allow the clinician to detect patients at risk and may help us to tailor the medical therapy and discharge strategy according to myocardial damage. Because of the number of indices, it is difficult to properly evaluate new therapeutics or to adopt one index that will provide sufficient data to better evaluate and understand the part of the coronary vasculature that is not seen - the microcirculation or so-called "black box". The aim of this review is to describe the non-invasive and invasive indices used to describe the microcirculation and their ability to predict clinical impact, and current dedicated therapeutics that may help to reduce microvascular damage and improve clinical outcomes.
Asunto(s)
Cateterismo Cardíaco , Técnicas de Imagen Cardíaca , Circulación Coronaria , Electrocardiografía , Microcirculación , Isquemia Miocárdica/diagnóstico , Velocidad del Flujo Sanguíneo , Fármacos Cardiovasculares/uso terapéutico , Circulación Coronaria/efectos de los fármacos , Reserva del Flujo Fraccional Miocárdico , Humanos , Microcirculación/efectos de los fármacos , Isquemia Miocárdica/tratamiento farmacológico , Isquemia Miocárdica/fisiopatología , Valor Predictivo de las Pruebas , Pronóstico , Resistencia VascularRESUMEN
We report 2 cases of right pulmonary aplasia with left pulmonary artery sling responsible for severe respiratory symptoms. Repositioning of the left pulmonary artery without tracheal surgery was successful in both patients. The postoperative course was simple, and the outcome was favorable at last follow-up (after 2 years and 3 months, respectively). Computed tomography provided an accurate diagnostic evaluation that helped to choose the best surgical technique.
Asunto(s)
Pulmón/anomalías , Arteria Pulmonar/anomalías , Procedimientos Quirúrgicos Vasculares/métodos , Anomalías Múltiples , Hiperreactividad Bronquial/etiología , Broncomalacia/etiología , Broncomalacia/terapia , Broncoscopía , Puente Cardiopulmonar , Femenino , Hernia/congénito , Hernia/etiología , Humanos , Recién Nacido , Riñón/anomalías , Pulmón/irrigación sanguínea , Pulmón/diagnóstico por imagen , Arteria Pulmonar/diagnóstico por imagen , Arteria Pulmonar/cirugía , Costillas/anomalías , Vértebras Torácicas/anomalías , Tomografía Computarizada Espiral , Tráquea/anomalías , Ultrasonografía PrenatalRESUMEN
OBJECTIVES: A detailed preoperative evaluation of coronary anatomy is mandatory before surgical intervention for tetralogy of Fallot. In pediatric patients, the preoperative evaluation of coronary anatomy has relied classically on conventional angiographic analysis and, more recently, on echocardiographic analysis, which have well-known limitations and complications. Recent technological improvements allow the use of multislice computed tomographic analysis to evaluate coronary artery anatomy in very young children, even those with high heart rates. The purpose of this prospective study was to assess the accuracy of preoperative dual-source computed tomographic analysis in detecting coronary artery abnormalities by using surgical findings as the reference standard. METHODS: We prospectively evaluated 100 patients with tetralogy of Fallot before surgical intervention between November 2006 and September 2009 by using dual-source computed tomographic analysis with either retrospective, electrocardiographically gated, helical computed tomographic analysis or prospective, electrocardiographically triggered, sequential computed tomographic acquisition. The patients had a median age of 6.8 months (range, 1.2 months-6.8 years) and a median weight of 7.9 kg (range, 3-30 kg). RESULTS: Compared with surgical findings, dual-source computed tomographic analysis had 100% sensitivity and 100% specificity for detecting coronary artery abnormalities. Major coronary artery abnormalities were found in 7 (7%) patients. The radiation dose was low. CONCLUSIONS: Dual-source computed tomographic analysis is an accurate and noninvasive tool for delineating coronary artery anatomy before surgical intervention in children with tetralogy of Fallot. Dual-source computed tomographic analysis might deserve to be used routinely instead of angiographic analysis and in combination with echocardiographic analysis for the preoperative assessment of patients with tetralogy of Fallot.
Asunto(s)
Técnicas de Imagen Sincronizada Cardíacas , Angiografía Coronaria/métodos , Anomalías de los Vasos Coronarios/diagnóstico por imagen , Tetralogía de Fallot/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Procedimientos Quirúrgicos Cardíacos , Niño , Preescolar , Anomalías de los Vasos Coronarios/cirugía , Femenino , Francia , Humanos , Lactante , Masculino , Valor Predictivo de las Pruebas , Cuidados Preoperatorios , Estudios Prospectivos , Dosis de Radiación , Sensibilidad y Especificidad , Tetralogía de Fallot/cirugía , Tomografía Computarizada Espiral , UltrasonografíaRESUMEN
BACKGROUNDS: We evaluate the feasibility and safety of coronary computed tomography angiography (CCTA) as the first-line investigation in heart transplant patients and the rate of coronary allograft vasculopathy detected using CCTA. METHODS: From September 2003 to June 2009, we prospectively included 65 heart transplant recipients, retaining 62 who underwent yearly CCTA for coronary allograft vasculopathy detection (261 CCTAs). We used 16-slice, 64-slice, and 2×64-slice CT machines. Patients with coronary artery stenosis by CCTA had a confirmation and a further follow-up exclusively by conventional coronary angiography (CCA). RESULTS: No major coronary events occurred during the study. Of the 62 baseline CCTAs, 37 (60%) were normal, 18 (29%) showed wall thickening, and 7 (11%) known significant stenosis, confirmed by CCA. The mean follow-up duration was 5 years. At the last follow-up, 26 (70%) patients with normal baseline findings remained normal, 9 (24%) had wall thickening, and 2 (6%) significant stenoses. Time to stenosis was consistently greater than 3 years. Of the 18 patients with initially wall thickening, 14 (78%) had wall thickening and 4 (22%) significant stenosis at last follow-up. The mean interval without any coronary lesion was 9.46±3.98 years. The mean interval without de novo significant stenosis was 10.31±4 years. CONCLUSIONS: CCTA seems to be a safe noninvasive tool for monitoring heart transplant patients, and thus obviating the need for CCA. In patients with normal baseline CCTA, a 2-year interval between CCTAs may be safe.
Asunto(s)
Angiografía/métodos , Enfermedad de la Arteria Coronaria/diagnóstico por imagen , Cardiopatías/cirugía , Trasplante de Corazón , Tomografía Computarizada Espiral/métodos , Adolescente , Adulto , Anciano , Angiografía/efectos adversos , Niño , Preescolar , Angiografía Coronaria , Enfermedad de la Arteria Coronaria/epidemiología , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Lactante , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias , Pronóstico , Estudios Prospectivos , Estudios Retrospectivos , Tomografía Computarizada Espiral/efectos adversos , Resultado del Tratamiento , Adulto JovenRESUMEN
BACKGROUND: For coronary artery visualization, retrospective ECG-gated acquisition by dual-source computed tomography (DSCT) was superior to spiral non-ECG-gated acquisition in a paediatric population of congenital heart disease (CHD) patients. However, retrospective cardiac CT is associated with substantial radiation doses to the patient. Recently, DSCT with end-systolic reconstruction was found to be robust for imaging the coronary arteries in patients with high heart rates. OBJECTIVE: To evaluate step-and-shoot DSCT with end-systolic reconstruction for evaluating the heart, coronary arteries and other thoracic structures in young children with CHD. MATERIALS AND METHODS: All neonates and children younger than 6 years of age who were referred to our institution for CHD evaluation between September and October 2009 were included in the study. ECG-gated DSCT was performed in sequential prospective mode centred on the systolic phase identified by ECG analysis. To assess the radiation dose, we recorded the dose-length product (DLP) in mGy·cm and the effective dose in mSv estimated from the DLP. Overall image quality was evaluated using a 5-grade scoring system and was assessed by looking at cardiac and vascular structures. The image quality for the proximal and middle segments of the right and left coronary arteries was also evaluated using a 5-grade scale. RESULTS: Images of diagnostic quality (grade ≥ 3) were obtained in all 30 children with a mean image quality grade of 4.7 ± 0.6 (range, 3-5). Mean DLP was 5.7 ± 4.8 mGy*cm (range, 1-22 mGy cm) and mean effective radiation dose was 0.26 ± 0.16 mSv (range, 0.05-0.8 mSv). CONCLUSION: Prospective ECG-gated thoracic DSCT at end-systole usually provides adequate thoracic and coronary artery image quality in neonates, infants and young children with CHD, independent of heart rate. This new method is associated with lower radiation doses compared to previous literature (mean effective dose, 0.26 mSv).
Asunto(s)
Técnicas de Imagen Sincronizada Cardíacas/métodos , Angiografía Coronaria/métodos , Cardiopatías Congénitas/diagnóstico por imagen , Dosis de Radiación , Radiografía Torácica/métodos , Tomografía Computarizada por Rayos X/métodos , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Reproducibilidad de los Resultados , Sensibilidad y EspecificidadRESUMEN
OBJECTIVES: To prospectively assess the value of multidetector computed tomography (MDCT) for detecting partial anomalous pulmonary venous return (PAPVR) in children with suspected sinus venosus-atrial septal defect (SV-ASD). METHODS: Forty-four children (mean age, 7.3 years; range, nine months-16 years) from whom transthoracic echocardiography (TTE) was inconclusive for the diagnosis underwent MDCT after contrast medium injection. Diagnosis was suspected on TTE by abnormal pulmonary venous return, no visualization of pulmonary venous ostia, or unexpected dilatation of right cavities. The first 11 children also underwent cardiac catheterization. Surgical findings constituted the diagnostic reference standard. RESULTS: Thirty-two (73%) children had SV-ASD with PAPVR. Of the first 11 patients, one had PAPVR by MDCT and 10 by conventional angiography; these 11 patients had PAPVR by surgery. Of the remaining 33 patients, 21 had SV-ASD and 12 had ostium secundum ASD, by both MDCT and surgery. MDCT had 100% sensitivity, 100% specificity, 100% positive predictive value, and 100% negative predictive value for diagnosing PAPVR in patients with suspected SV-ASD. CONCLUSION: Contrast-enhanced MDCT is a highly accurate, minimally-invasive technique for detecting PAPVR associated with SV-ASD. Contrast-enhanced MDCT may be used safely to replace conventional angiography for the definitive diagnosis and preoperative evaluation of children with suspected SV-ASD.
Asunto(s)
Cuidados Preoperatorios/métodos , Venas Pulmonares/anomalías , Intensificación de Imagen Radiográfica , Tomografía Computarizada Espiral/métodos , Adolescente , Procedimientos Quirúrgicos Cardíacos/métodos , Niño , Preescolar , Intervalos de Confianza , Femenino , Defectos del Tabique Interatrial/diagnóstico por imagen , Defectos del Tabique Interatrial/cirugía , Humanos , Lactante , Masculino , Valor Predictivo de las Pruebas , Estudios Prospectivos , Venas Pulmonares/diagnóstico por imagen , Sensibilidad y EspecificidadRESUMEN
Multidetector CT (MDCT) is increasingly used for imaging congenital heart disease (CHD) patients in addition to echocardiography, due to its ability to provide high quality three-dimensional images, giving a comprehensive evaluation of complex heart malformations. Using 4-slice or 16-slice CT, diagnostic information in CHD patients is limited to extra-cardiac anatomy, mainly the pulmonary arteries, aorta and venous connections. Due to high heart rates in babies however, coronary evaluation and intra-cardiac analysis were not reliable with the first generations of MDCT. Larger detector size with 64-slice CT and faster acquisition time, up to 75 ms for one slice, has progressively improved coronary and intra-cardiac visualization. Because radiation dose is the main concern, especially in children, every attempt to minimize dose whilst preserving image quality is important: the ALARA concept should always be applied in this population. The 80 kVp setting is now well accepted as a standard for more and more radiological teams involved in CT of children. Different acquisition strategies are now possible for childhood coronary imaging, using retrospective or even prospective gating. Using the latest technology, sub-mSv acquisitions are now attainable for scanning a whole thorax, providing a complete analysis of any 3-D cardiac malformation, including coronary artery course visualisation. This review will describe how technological developments have improved image quality with continuous reduction of radiation dose.
Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Cardiopatías Congénitas/diagnóstico por imagen , Radiología/tendencias , Tomografía Computarizada por Rayos X/métodos , Tomografía Computarizada por Rayos X/tendencias , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Estados UnidosRESUMEN
OBJECTIVES: Reconstruction of cardiac computed tomography (CT) images is challenging when the heart rate is higher than 65 beats per minute (bpm). The optimal reconstruction time is often found to be at the end-systolic phase, but image quality remains uncertain. Using dual-source (DS) CT and 83-ms temporal resolution, we evaluated the robustness of the temporal window with low motion during the end systole. METHODS: We studied 41 DSCT in consecutive patients with a heart rate >65 bpm. Eleven systolic reconstructions were performed every 20 ms between 200 ms and 400 ms of the R-R interval. The end-systolic temporal window (ESTW) was defined as the interval between the first and last selected phases judged adequate for diagnosis. RESULTS: Heart rates varied from 67 to 150 bpm. ESTW was always to be found greater than 100 ms. The mean ESTW was 178 ms (SD: 57 ms), and varied independently of heart rate. All data sets achieved diagnostic quality during the end-systolic phase at a time point between 35 and 50% of the R-R interval. CONCLUSION: Our data suggest that CT with a temporal window below 100 ms may provide acceptable systolic reconstructions at any heart rate, in a large proportion of patients.
Asunto(s)
Técnicas de Imagen Sincronizada Cardíacas/métodos , Angiografía Coronaria/métodos , Enfermedad Coronaria/diagnóstico por imagen , Frecuencia Cardíaca/fisiología , Interpretación de Imagen Radiográfica Asistida por Computador/métodos , Tomografía Computarizada por Rayos X/métodos , Medios de Contraste , Femenino , Humanos , Imagenología Tridimensional , Yopamidol/análogos & derivados , Masculino , Intensificación de Imagen Radiográfica/métodos , SístoleRESUMEN
We have been confronted with patients in whom classical techniques did not offer optimum exposure to correct supracardiac forms of total anomalous pulmonary venous connection, especially in neonates. Therefore, we present a surgical modification of the superior approach for enhanced exposure as a result of transection of the ascending aorta associated or not with the transection of the pulmonary trunk. The transaortopulmonary approach ensures a perfect exposition without any need to pull on the surrounding structures. Because of the better exposure, most patients do not require circulatory arrest.
Asunto(s)
Anastomosis Quirúrgica/métodos , Aorta/cirugía , Atrios Cardíacos/cirugía , Cardiopatías Congénitas/cirugía , Arteria Pulmonar/cirugía , Venas Pulmonares/anomalías , Puente Cardiopulmonar , Cardiopatías Congénitas/mortalidad , Humanos , Lactante , Recién Nacido , Complicaciones Posoperatorias/mortalidad , Complicaciones Posoperatorias/cirugía , Venas Pulmonares/cirugía , Enfermedad Veno-Oclusiva Pulmonar/mortalidad , Enfermedad Veno-Oclusiva Pulmonar/cirugía , ReoperaciónAsunto(s)
Anomalías Múltiples/cirugía , Defecto del Tabique Aortopulmonar/cirugía , Anomalías de los Vasos Coronarios/cirugía , Anomalías Múltiples/diagnóstico , Insuficiencia de la Válvula Aórtica/etiología , Insuficiencia de la Válvula Aórtica/cirugía , Defecto del Tabique Aortopulmonar/complicaciones , Defecto del Tabique Aortopulmonar/diagnóstico , Niño , Anomalías de los Vasos Coronarios/diagnóstico , Femenino , Humanos , Lactante , Masculino , Insuficiencia de la Válvula Mitral/etiología , Insuficiencia de la Válvula Mitral/cirugía , Arteria Pulmonar/cirugíaRESUMEN
Slide tracheoplasty can be applied successfully to all types of long segment congenital tracheal stenosis. In case of short segment tracheal stenosis, direct resection and anastomosis is often preferred. We report a case illustrating a new side benefit of the slide tracheoplasty in a patient presenting a relatively short hypoplastic tracheal segment coexisting with tracheomalacia after EA with TEF repair.
Asunto(s)
Atresia Esofágica/complicaciones , Procedimientos de Cirugía Plástica/métodos , Tráquea/cirugía , Estenosis Traqueal/cirugía , Traqueomalacia/cirugía , Anastomosis Quirúrgica/métodos , Diagnóstico Diferencial , Atresia Esofágica/diagnóstico , Atresia Esofágica/cirugía , Estudios de Seguimiento , Humanos , Lactante , Masculino , Estenosis Traqueal/congénito , Estenosis Traqueal/diagnóstico , Traqueomalacia/diagnóstico , Traqueomalacia/etiologíaRESUMEN
Malformation of the aortic arch system has been described in details by Stewart et al. in 1964. Innominate artery originating via the ductus arteriosus from the pulmonary artery is a very rare type of congenital aortic arch anomaly that has been seldomly reported. We report the case of an aortic arch anomaly revealed by a pulmonary hypertension because of left to right shunt. Surgical procedure was performed through a median sternotomy, without cardiopulmonary bypass. After section. of the ductus arteriosus, the left innominate artery was extensively dissected and mobilized to be implanted on the left side of the ascending aorta under lateral clamping.
Asunto(s)
Aorta Torácica/anomalías , Tronco Braquiocefálico/anomalías , Conducto Arterioso Permeable/cirugía , Hipertensión Pulmonar/etiología , Malformaciones Vasculares/complicaciones , Anomalías Múltiples/diagnóstico , Anomalías Múltiples/cirugía , Angiografía/métodos , Aorta Torácica/cirugía , Tronco Braquiocefálico/cirugía , Cateterismo Cardíaco/métodos , Procedimientos Quirúrgicos Cardíacos/métodos , Preescolar , Terapia Combinada , Conducto Arterioso Permeable/complicaciones , Conducto Arterioso Permeable/diagnóstico , Femenino , Estudios de Seguimiento , Humanos , Hipertensión Pulmonar/fisiopatología , Imagenología Tridimensional , Medición de Riesgo , Factores de Tiempo , Tomografía Computarizada por Rayos X , Resultado del Tratamiento , Malformaciones Vasculares/diagnóstico por imagen , Malformaciones Vasculares/cirugía , Procedimientos Quirúrgicos Vasculares/métodosRESUMEN
BACKGROUND: There are only a few reports on the diagnostic accuracy, and the technical and clinical feasibility, of multidetector CT (MDCT) in infants with congenital heart disease (CHD). OBJECTIVE: To evaluate the image quality and radiation dose of DSCT in babies with CHD. MATERIALS AND METHODS: From November 2006 to November 2007, 110 consecutive infants with CHD referred for pre- or postoperative CT evaluation were included. All these infants had a spiral angiothoracic DSCT scan after injection of 300 mg/ml iopromide at 0.5-1 ml/s with a power injector using a low-dose protocol (80 kVp and 10 mAs/kg). Of these infants, 34 also underwent an ECG-gated coronary CT scan for evaluation of the course of the coronary arteries. RESULTS: No serious adverse events were recorded. The mean dose-length product was 8+/-6 mGy x cm (effective dose 0.5+/-0.2 mSv) and 21+/-9 mGy x cm (effective dose 1.3+/-0.6 mSv) during the non-ECG-gated spiral acquisition and ECG-gated acquisition, respectively. Diagnostic quality images were achieved with the spiral acquisition in 89% of cases. Compared to the spiral mode, ECG-gated acquisition significantly improved the visualization of the coronary arteries, with a diagnostic rate of 91% and 84% for the left and right coronary arteries, respectively. CONCLUSION: DSCT together with iopromide at 300 mg/ml is a valuable tool for the routine clinical evaluation of infants with CHD. ECG-gated acquisition provides reliable visualization of the course of the coronary arteries.
Asunto(s)
Carga Corporal (Radioterapia) , Angiografía Coronaria/métodos , Cardiopatías Congénitas/diagnóstico por imagen , Intensificación de Imagen Radiográfica/métodos , Radiografía Torácica/métodos , Tomografía Computarizada por Rayos X/métodos , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Dosis de Radiación , Efectividad Biológica Relativa , Reproducibilidad de los Resultados , Sensibilidad y EspecificidadRESUMEN
OBJECTIVE: Postoperative left ventricular outflow tract obstruction (LVOTO) after arterial switch operation (ASO) is rare. In this retrospective study, we reviewed the cases of 10 patients with LVOTOs post-ASO and analyzed the options used for the LVOTOs corrections and the patients' outcomes. METHODS: From December 1982 to December 2006, 1689 consecutive ASO were performed. Ten patients presented with postoperative LVOTOs (0.59% of all ASO and 7.62% of ASO for Taussig-Bing anomaly (TBA)) leading to reoperations. Before ASO they presented with significant subaortic gradients (n=4) or predisposing anatomical features (n=9) such as: conal septum malalignment (7/9), abnormal tricuspid cords insertions (4/9), muscular bundle hypertrophy (3/9) and mitral accessory tissue (2/9). RESULTS: No patient was lost in the follow-up: 117+/-33 months. Subaortic gradients had developed between 5 months and 14 years after ASO (mean 41+/-35 months) leading to reoperations. Most LVOTOs post-ASO were due to fibrotic membranes or fibro-muscular hypertrophy, removed at first reoperation. After their first reoperations, seven patients (70%) had non-significant or low gradients and were not reoperated for LVOTO. Three patients underwent iterative surgical procedures for LVOTOs leading to two aortic valve replacements associated with LVOTO release or Konno procedure. CONCLUSION: Postoperative LVOTO after ASO is rare but happens more frequently in TBA. Most of them can benefit from resections of subaortic obstacles or septal plasties. In more complex cases iterative surgical procedures may lead to complications such as block or severe aortic valve regurgitation.
Asunto(s)
Defectos del Tabique Interventricular/cirugía , Complicaciones Posoperatorias/etiología , Transposición de los Grandes Vasos/cirugía , Obstrucción del Flujo Ventricular Externo/cirugía , Métodos Epidemiológicos , Femenino , Defectos del Tabique Interventricular/complicaciones , Humanos , Lactante , Recién Nacido , Masculino , Complicaciones Posoperatorias/diagnóstico por imagen , Reoperación/métodos , Tomografía Computarizada por Rayos X , Transposición de los Grandes Vasos/complicaciones , Transposición de los Grandes Vasos/diagnóstico por imagen , Resultado del Tratamiento , Obstrucción del Flujo Ventricular Externo/diagnóstico por imagen , Obstrucción del Flujo Ventricular Externo/etiologíaRESUMEN
AIMS: We evaluated the accuracy of 64-slice computed tomography (CT) to identify ischaemic aetiology of heart failure (IHF). METHODS AND RESULTS: Ninety-three consecutive patients in sinus rhythm with dilated cardiomyopathy but without suspicion of coronary artery disease (CAD) were enrolled when admitted for angiography. Accuracy of CT to detect significant stenosis (>50% lumen narrowing) was compared with quantitative coronary angiography. IHF was defined as a significant stenosis on left main or proximal left anterior descending artery or two or more vessels. Forty-three out of 1395 segments (3%) were heavily calcified and excluded. CT correctly assessed 103 of 142 (73%) significant stenosis and identified 46 of 50 (92%) patients without and 42 of 43 (98%) patients with CAD, 60 of 62 (97%) patients without and 28 of 31 (90%) patients with IHF. Overall, accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of CT for identifying CAD by segment was 96, 73, 99, 92, and 97%, respectively; by patient was 95, 98, 92, 91, and 98%, respectively; and for identifying IHF was 95, 90, 97, 93, and 95%, respectively. CONCLUSION: Non-invasive 64-slice CT assessment of the extent of CAD may offer a valid alternative to angiography for the diagnosis of IHF.