Medical Data Analysis Meets Artificial Intelligence (AI) and Internet of Medical Things (IoMT).

AI is a contemporary methodology rooted in the field of computer science [...].

A new efficient referential genome compression technique for FastQ files.

Hospitals and medical laboratories create a tremendous amount of genome sequence data every day for use in research, surgery, and illness diagnosis. To make storage comprehensible, compression is therefore essential for the storage, monitoring, and distribution of all these data. A novel data compression technique is required to reduce the time as well as the cost of storage, transmission, and data processing. General-purpose compression techniques do not perform so well for these data due to their special features: a large number of repeats (tandem and palindrome), small alphabets, and highly similar, and specific file formats. In this study, we provide a method for compressing FastQ files that uses a reference genome as a backup without sacrificing data quality. FastQ files are initially split into three streams (identifier, sequence, and quality score), each of which receives its own compression technique. A novel quick and lightweight mapping mechanism is also presented to effectively compress the sequence stream. As shown by experiments, the suggested methods, both the compression ratio and the compression/decompression duration of NGS data compressed using RBFQC, are superior to those achieved by other state-of-the-art genome compression methods. In comparison to GZIP, RBFQC may achieve a compression ratio of 80-140% for fixed-length datasets and 80-125% for variable-length datasets. Compared to domain-specific FastQ file referential genome compression techniques, RBFQC has a compression and decompression speed (total) improvement of 10-25%.

Diabetic Foot Ulcer Identification: A Review.

Diabetes is a chronic condition caused by an uncontrolled blood sugar levels in the human body. Its early diagnosis may prevent severe complications such as diabetic foot ulcers (DFUs). A DFU is a critical condition that can lead to the amputation of a diabetic patient's lower limb. The diagnosis of DFU is very complicated for the medical professional as it often goes through several costly and time-consuming clinical procedures. In the age of data deluge, the application of deep learning, machine learning, and computer vision techniques have provided various solutions for assisting clinicians in making more reliable and faster diagnostic decisions. Therefore, the automatic identification of DFU has recently received more attention from the research community. The wound characteristics and visual perceptions with respect to computer vision and deep learning, especially convolutional neural network (CNN) approaches, have provided potential solutions for DFU diagnosis. These approaches have the potential to be quite helpful in current medical practices. Therefore, a detailed comprehensive study of such existing approaches was required. The article aimed to provide researchers with a detailed current status of automatic DFU identification tasks. Multiple observations have been made from existing works, such as the use of traditional ML and advanced DL techniques being necessary to help clinicians make faster and more reliable diagnostic decisions. In traditional ML approaches, image features provide signification information about DFU wounds and help with accurate identification. However, advanced DL approaches have proven to be more promising than ML approaches. The CNN-based solutions proposed by various authors have dominated the problem domain. An interested researcher will successfully be able identify the overall idea in the DFU identification task, and this article will help them finalize the future research goal.

Multimodality Medical Image Fusion Using Clustered Dictionary Learning in Non-Subsampled Shearlet Transform.

Imaging data fusion is becoming a bottleneck in clinical applications and translational research in medical imaging. This study aims to incorporate a novel multimodality medical image fusion technique into the shearlet domain. The proposed method uses the non-subsampled shearlet transform (NSST) to extract both low- and high-frequency image components. A novel approach is proposed for fusing low-frequency components using a modified sum-modified Laplacian (MSML)-based clustered dictionary learning technique. In the NSST domain, directed contrast can be used to fuse high-frequency coefficients. Using the inverse NSST method, a multimodal medical image is obtained. Compared to state-of-the-art fusion techniques, the proposed method provides superior edge preservation. According to performance metrics, the proposed method is shown to be approximately 10% better than existing methods in terms of standard deviation, mutual information, etc. Additionally, the proposed method produces excellent visual results regarding edge preservation, texture preservation, and more information.

A Non-Conventional Review on Multi-Modality-Based Medical Image Fusion.

Today, medical images play a crucial role in obtaining relevant medical information for clinical purposes. However, the quality of medical images must be analyzed and improved. Various factors affect the quality of medical images at the time of medical image reconstruction. To obtain the most clinically relevant information, multi-modality-based image fusion is beneficial. Nevertheless, numerous multi-modality-based image fusion techniques are present in the literature. Each method has its assumptions, merits, and barriers. This paper critically analyses some sizable non-conventional work within multi-modality-based image fusion. Often, researchers seek help in apprehending multi-modality-based image fusion and choosing an appropriate multi-modality-based image fusion approach; this is unique to their cause. Hence, this paper briefly introduces multi-modality-based image fusion and non-conventional methods of multi-modality-based image fusion. This paper also signifies the merits and downsides of multi-modality-based image fusion.

Low-dose COVID-19 CT Image Denoising Using CNN and its Method Noise Thresholding.

Noise in computed tomography (CT) images may occur due to low radiation doses. Hence, the main aim of this paper is to reduce the noise from low-dose CT images so that the risk of high radiation dose can be reduced. BACKGROUND: The novel coronavirus outbreak has ushered in different new areas of research in medical instrumentation and technology. Medical diagnostics and imaging are one of the ways in which the area and level of infection can be detected. OBJECTIVE: COVID-19 attacks people with less immunity, so infants, kids, and pregnant women are more vulnerable to the infection. So, they need to undergo CT scanning to find the infection level. But the high radiation diagnostic is also fatal for them, so the intensity of radiation needs to be reduced significantly, which may generate the noise in the CT images. METHOD: This paper introduces a new denoising technique for low-dose Covid-19 CT images using a convolution neural network (CNN) and noise-based thresholding method. The major concern of the methodology for reducing the risk associated with radiation while diagnosing. RESULTS: The results are evaluated visually and using standard performance metrics. From comparative analysis, it was observed that proposed works give better outcomes. CONCLUSION: The proposed low-dose COVID-19 CT image denoising model is therefore concluded to have a better potential to be effective in various pragmatic medical image processing applications in noise suppression and clinical edge preservation.

Noise Suppression and Edge Preservation for Low-Dose COVID-19 CT Images Using NLM and Method Noise Thresholding in Shearlet Domain.

In the COVID-19 era, it may be possible to detect COVID-19 by detecting lesions in scans, i.e., ground-glass opacity, consolidation, nodules, reticulation, or thickened interlobular septa, and lesion distribution, but it becomes difficult at the early stages due to embryonic lesion growth and the restricted use of high dose X-ray detection. Therefore, it may be possible for a patient who may or may not be infected with coronavirus to consider using high-dose X-rays, but it may cause more risks. Conclusively, using low-dose X-rays to produce CT scans and then adding a rigorous denoising algorithm to the scans is the best way to protect patients from side effects or a high dose X-ray when diagnosing coronavirus involvement early. Hence, this paper proposed a denoising scheme using an NLM filter and method noise thresholding concept in the shearlet domain for noisy COVID CT images. Low-dose COVID CT images can be further utilized. The results and comparative analysis showed that, in most cases, the proposed method gives better outcomes than existing ones.

RST-DE: Rough Sets-Based New Differential Evolution Algorithm for Scalable Big Data Feature Selection in Distributed Computing Platforms.

In data analysis, data scientists usually focus on the size of data instead of features selection. Owing to the extreme growth of internet resources data are growing exponentially with more features, which leads to big data dimensionality problems. The high volume of features contains much of redundant data, which may affect the feature classification in terms of accuracy. In the current scenario, feature selection attracts the research community to identify and to remove irrelevant features with more scalability and accuracy. To accommodate this, in this research study, we present a novel feature selection framework that is implemented on Hadoop and Apache Spark platform. In contrast, the proposed model also includes rough sets and differential evolution (DE) algorithm, where rough sets are used to find the minimum features, but rough sets do not consider the degree of overlying in the data. Therefore, DE algorithm is used to find the most optimal features. The proposed model is studied with Random Forest and Naive Bayes classifiers on five well-known data sets and compared with existing feature selection models presented in the literature. The results show that the proposed model performs well in terms of scalability and accuracy.

Predicting the time period of extension of lockdown due to increase in rate of COVID-19 cases in India using machine learning.

The research paper proposes a methodology to predict the extension of lockdown in order to eradicate COVID-19 from India. All the concepts related to Coronavirus, its history, prevention and cure is explained in the research paper. Concept used to predict the number of active cases, deaths and recovery is Linear Regression which is an application of machine learning. Extension of lockdown is predicted on the basis of predicted number of active cases, deaths and recovery all over India. To predict the number of active cases, deaths and recovery, date wise analysis of current data was done and necessary parameters like daily recovery, daily deaths, increase rate of covid-19 cases were included. Graphical representation of each analysis and prediction was done in order to make predicted results more understandable. The combined analysis was performed at the end which included the final result of total cases of coronavirus in India. Combined analysis included the no. of cases from start of COVID-19 to the predicted end of cases all over India.