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1.
Eur J Clin Pharmacol ; 51(5): 355-8, 1997.
Artículo en Inglés | MEDLINE | ID: mdl-9049574

RESUMEN

OBJECTIVE: A randomised, controlled clinical trial was performed to study the long-term effect of gradual withdrawal from benzodiazepines on the daily functioning of residents of homes for the elderly. The planned sample size was not achieved due to recruitment and follow-up problems. RESULTS: The results in this small sample nevertheless suggest that gradual withdrawal from benzodiazepines is possible in residents of homes for the elderly, and that it can have a positive effect on their daily functioning. No major withdrawal symptoms were observed, although there was a decrease in sleep quality during withdrawal. CONCLUSION: The findings are promising for further research, but researchers should anticipate the problems inherent in executing a trial with institutionalised elderly subjects.


Asunto(s)
Benzodiazepinas/administración & dosificación , Síndrome de Abstinencia a Sustancias , Anciano , Anciano de 80 o más Años , Cognición/efectos de los fármacos , Método Doble Ciego , Utilización de Medicamentos , Estudios de Factibilidad , Femenino , Hogares para Ancianos , Humanos , Masculino , Pautas de la Práctica en Medicina , Trastornos del Inicio y del Mantenimiento del Sueño/tratamiento farmacológico , Factores de Tiempo
2.
Tijdschr Gerontol Geriatr ; 26(6): 253-8, 1995 Dec.
Artículo en Holandés | MEDLINE | ID: mdl-8553435

RESUMEN

The Dutch Behaviour Observation Scale-Geriatrics (GOS-G) is designed to give a detailed description of the functioning of geriatric patients. This article reports the psychometric properties of the GOS-G for use in homes for the elderly. Analysed were data on 71 residents of 11 homes (they participated in a study on withdrawal of benzodiazepines). They were free of serious physical and psychological complaints. For 55 persons from 10 different homes the observation scale was filled out by two different care takers at three different occasions: twice at the start of the study with a time interval of one to three weeks, and once more after eight months. Sixteen residents from another rest home were evaluated with the GOS-G by two different care takers at one occasion. The findings in this selective sample suggest the total scale to be a reliable and valid measure of the daily functioning in homes for the elderly. Moreover, the total scale appears sensitive to change. The scores on the subscales 'psychotic behaviour' and 'disoriented behaviour' were unreliable. Observation of a more heterogeneous and larger sample is needed to confirm the usefulness of the GOS-G in homes for the elderly.


Asunto(s)
Anciano/psicología , Evaluación Geriátrica , Pruebas Neuropsicológicas , Conducta Social , Actividades Cotidianas , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Casas de Salud , Reproducibilidad de los Resultados , Sensibilidad y Especificidad
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