[Clinico-bacteriologic and immunologic characteristics of healthy newborn infants and their mothers]. / Kliniko-bakteriologicheskaia i immunologicheskaia kharakteristika zdorovykh novorozhdennykh i ikh materei.

A study was made of the establishment of biocenosis in the early neonatal period in healthy full-term neonates born to healthy mothers and in children belonging to a group at risk with an aggravated anamnesis but with no history of pyoinflammatory diseases. The study was related to bacterial colonization of the mother, amniotic fluid and placenta as well as to the immune status of the lying in woman and fetus. In 37% of children belonging to the group at risk, the minimal signs of intrauterine infection were discovered.

[Clinico-bacteriologic and immunologic criteria in the formation of suppurative-inflammatory pathology in newborn infants]. / Kliniko-bakteriologicheskie i immunologicheskie kriterii formirovaniia gnoino-vospalitel'noi patologii u novorozhdennykh detei.

Based on the results of clinico-bacteriological and immunological studies carried out in the early neonatal period in 65 neonates afflicted with pyoinflammatory diseases and in their mothers, diagnostic criteria for intrauterine and early neonatal infection were elaborated. The significance played in this process of the character and level of microbial colonization of the amniotic fluid, placenta, labor tract of the mother, intrauterine antigenic stimulation of the fetus, changes in the peripheral blood and inflammatory alterations in the placenta was defined. Clinical, bacteriological and immunological prognostic criteria for the risk of the development of pyoinflammatory diseases in neonates were elaborated.