RESUMEN
The United Kingdom achieved interrupted endemic measles transmission for 36 months in 2016. Despite this, ongoing challenges from sporadic measles cases typically imported from abroad remain. We summarise a B3 measles genotype outbreak in south-east Wales occurring between May and September 2017, linked with other European outbreaks, and lessons learnt. Seventeen confirmed cases and one probable case occurred principally in education and healthcare-settings. Six confirmed cases attended healthcare settings when infectious, without being isolated.
Asunto(s)
Brotes de Enfermedades/prevención & control , Virus del Sarampión/clasificación , Virus del Sarampión/genética , Sarampión/epidemiología , Adolescente , Niño , Preescolar , Control de Enfermedades Transmisibles , Trazado de Contacto , Femenino , Genotipo , Humanos , Masculino , Sarampión/diagnóstico , Sarampión/prevención & control , Virus del Sarampión/aislamiento & purificación , Reacción en Cadena de la Polimerasa , Análisis de Secuencia , Reino Unido/epidemiología , Vacunación/estadística & datos numéricos , Gales/epidemiologíaRESUMEN
We describe a longitudinal study carried out in an adult outbreak-associated cohort to investigate health effects, including post-infectious irritable bowel syndrome, occurring after resolution of acute Cryptosporidium parvum infection. New symptoms self-reported up to 12 months included: weight loss (31â%), abdominal pain (38â%), diarrhoea (33â%), eye pain (9â%), joint pain (33â%), fatigue (22â%) and symptoms consistent with irritable bowel syndrome (IBS) (28â%). Two people were medically diagnosed with IBS. This study describes for the first time sequelae reported by patients up to 12 months after infection with C. parvum, which appear to be similar to those described with C. hominis.
Asunto(s)
Criptosporidiosis/complicaciones , Criptosporidiosis/epidemiología , Cryptosporidium parvum , Brotes de Enfermedades , Adolescente , Adulto , Femenino , Humanos , Estudios Longitudinales , Masculino , Encuestas y Cuestionarios , Reino Unido , Adulto JovenRESUMEN
We report a cluster of atypical Guillain-Barré syndrome in 10 adults temporally related to a cluster of four children with acute flaccid paralysis, over a 3-month period in South Wales, United Kingdom. All adult cases were male, aged between 24 and 77 years. Seven had prominent facial diplegia at onset. Available electrophysiological studies showed axonal involvement in five adults. Seven reported various forms of respiratory disease before onset of neurological symptoms. The ages of children ranged from one to 13 years, three of the four were two years old or younger. Enterovirus testing is available for three children; two had evidence of enterovirus D68 infection in stool or respiratory samples. We describe the clinical features, epidemiology and state of current investigations for these unusual clusters of illness.