RESUMEN
Overall thirty-eight patients with exertional angina who had episodes of asymptomatic change of position of T-segment were examined. The above patients were divided into two groups: group I was placed on anaprilin treatment (80-120 mg daily), group II received corinfar (60 mg daily). Episodes of asymptomatic ischemia of the myocardium (AIM) showed two peaks in their 24 h-span occurrence, with the greatest number of these being recordable in early morning hours (from six a.m. to noon), somewhat less--within the time span 12 o'clock-0.6 p.m. Anaprilin monotherapy is more effective than corinfar monotherapy in respect to reduction of AIM episodes occurrences. However, corinfar, unlike anaprilin, prevented the appearance of the evening peak of episodes of "silent" ischemia.
Asunto(s)
Antagonistas Adrenérgicos beta/uso terapéutico , Bloqueadores de los Canales de Calcio/uso terapéutico , Isquemia Miocárdica/tratamiento farmacológico , Nifedipino/uso terapéutico , Propranolol/uso terapéutico , Adulto , Angina de Pecho/tratamiento farmacológico , Angina de Pecho/fisiopatología , Enfermedad Crónica , Ritmo Circadiano/efectos de los fármacos , Electrocardiografía/efectos de los fármacos , Humanos , Monitoreo Fisiológico , Isquemia Miocárdica/fisiopatología , Factores de TiempoAsunto(s)
Trasplante de Médula Ósea , Ensayo de Unidades Formadoras de Colonias , Conservación de Tejido , Animales , Células de la Médula Ósea , Diferenciación Celular/efectos de la radiación , Masculino , Ratones , Ratas , Bazo/citología , Bazo/efectos de la radiación , Temperatura , Trasplante HeterólogoRESUMEN
A study was made of the proliferative capacity of myelokariocytes of the rat bone marrow after freezing and thawing under protection of the oxyetyl derivative of the tetratomic alcohol; experiments were conducted on mouse-rat radiation chimerae. The rat bone marrow cells proved to retain their proliferative capacity.